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Monday, August 25, 2008

Request of information about treatment of type 1 (reversal) reaction

Leprosy Mailing List, August 25th, 2008

Ref.: Request of information about treatment of type 1 (reversal) reaction.
From: Ranawaka R., Anuradhapura, Sri Lanka


Dear Dr Salvatore,

I have two clinical problems which I would appreciate others experience in management. Herewith is described the second one. The first case was described in the previous message.

Patient 2; 60 year old women with lepromatous leprosy presented with type 1 reaction. She was treated with oral prednisolone for 3 months. At the tapering off of prednisolone she developed recurrence of type 1 reaction twice.

Is type 1 reaction described in lepromatous leprosy? Is there a recurrent type of this reaction? Is the 3 month course of oral prednisolone the standard treatment? LML collegue's experience in management of this condition will be greatly appreciated.

Kind regards,

Ranthilaka Ranawaka
Consultant Dermatologist
Teaching Hospital Anuradhapura
Sri Lanka

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