(LML) Patient with severe adverse effects due to steroids

Leprosy Mailing List – August 19,  2018

Ref.:    (LML) Patient with severe adverse effects due to steroids

From:  Ramesh Sharma, Pokhara, Nepal

---

Dear Pieter

 

 

We have a 40-year female patient with borderline tuberculoid leprosy with type 1 reaction under 3rd month of MB MDT. She developed cushingoid features with oral prednisolone and when the prednisolone was tapered bit fast, the reactions flared up. We then started clofazimine in a dose of 100 mg TDS few days back since I learned of it from a colleague. 

 

1. What could be the options in type 1 reaction when patients develop toxicity or severe adverse effects with steroid?

2. How effective or what is the evidence of clofazimine in type 1 reaction?

 

I work in a leprosy centre called Greenpastures Hospital, Pokhara, Nepal.

 

 

Regards,

 

Ramesh Sharma

 

Note editor:

The Google Group Leprosy Mailing List will start functioning from next week onwards. If you do not receive any communication from us the coming week, please contact me. Some of the emails bounced and could not be transferred to the Google Group LML. If you do not want to be a member of the Google Group LML but still wants to receive our messages, please let me know. I could put you on a special list. One also can always check our LML blog link: http://leprosymailinglist.blogspot.it/

 

---

LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com