Friday, January 17, 2025

Fw: Ref.: (LML) Leprosy research Initiative calls for proposals

 

Leprosy Mailing List –  January 17,  2025

 

Ref.:  (LML) Leprosy research Initiative calls for proposals

From:  LRI, Amsterdam, the Netherlands

Dear colleagues,

The LRI Secretariat wishes you a happy New Year! We are excited to share this first newsletter of 2025 which features the reminder for the research proposals submission deadline, LRI Spring Meeting dates and a Researcher spotlight.

 

LRI calls for proposals: Deadline for research proposals approaching!

The deadline for submission for both calls is Friday the 24th of January, 2025 at 17:00 (CET), after which the portal will be closed, so make sure to submit your Letter of Intent timely.

 

LRI Spring Meeting 2025 – Save the dates!
 

The LRI Spring Meeting is an annual event that brings together researchers of LRI-funded projects, the LRI Scientific Review Committee and Steering Committee as well as Partners of the LRI. More than 35 researchers will present project progress updates and results during this year's edition, which will take place online on the 9th and 10th of April (afternoons CET). The online event is open to everyone interested in leprosy research and will be free of charge.

 

 

 

Researcher spotlight 🌟  – Dr Suraj Maharjan, grantee of the LRI Research capacity strengthening grant
 

The first-ever call for proposals for the LRI Research capacity strengthening grant was announced in December 2022. After a rigorous selection process, the grant was awarded to two early-career researchers who submitted outstanding proposals. Among the recipients is Dr Suraj.

 
In his words "this grant has given me a big opportunity to research one of the neglected tropical diseases: leprosy. It has also opened up new insights, and allowed me to collaborate with different disciplines. Moreover, the contribution is to the bigger picture of the goal towards zero leprosy."
 
We asked Dr Suraj to share insights into his experience with his project, the grant and its focus on strengthening the capacity of early-career researchers and are excited to share his reflections:
 

📝📈 🔎 About the project:

"Early diagnosis and prevention of nerve damage remains one of the big challenges in leprosy. Autonomic impairment is an early sign of nerve damage that can be assessed by measurement of skin temperature with the help of infrared thermography. An infrared thermography test is non-invasive and independent of the patient or examiner's subjectivity. This test can have huge potential in the assessment and early diagnosis of leprosy."
 

📚🌟 How the grant has strengthened your capacity as an early-career researcher:

"This grant is very special as it is my first clinical research grant and a big opportunity for INF Green Pastures Hospital's leprosy work. I joined Green Pastures in 2017 as a reconstructive surgeon specialising in leprosy. My work on nerve damage and disability related to leprosy sparked my research interest, which is now being realized through this grant.
 
This grant has enabled me to initiate clinical research at the hospital as a Nepali clinician. This has also helped me to collaborate with different departments in our hospital inspiring other clinicians, healthcare workers, and staff to engage in research work.
 
I am privileged to be guided in this project by my teacher and mentor, leprosy expert Dr Wim Brandsma, who has not only helped me to deepen my understanding of leprosy and rehabilitation but also ignited my passion for research in this field. My dear friends and colleagues Dr Arjan Knulst (Biomedical Engineer) and Corine Verlaan Knulst (part of the research team) have been of wonderful support and constant push in making this endeavour a reality.
 
This research project has also allowed me to collaborate with likeminded people, government networks on leprosy and open doors for many more research ideas. Moreover, this opportunity has allowed me to manage the overall project, enhancing my skills in project management. I see great potential for expanding research through this project by fostering partnerships with like-minded organizations and collaborating with Nepal's government departments focused on leprosy and disability."

LRI wishes Dr Suraj a successful continuation of his project and development journey!
 
If you're an early-career researcher inspired by Dr Suraj's story, please submit your research proposal by January 24th for the LRI Research capacity strengthening grant.

 

LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

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Sunday, January 12, 2025

Fw: Ref.: (LML) Money for defeating HD

 

 

Leprosy Mailing List –  January 12,  2025

 

Ref.:  (LML) Money for defeating HD

From:  Joel Almeida, Mumbai, India

 

 

Dear Pieter and colleagues,

 

 

Brazilian colleagues have long been at the forefront of generating reliable scientific knowledge about HD (leprosy), its causes and consequences. Brazil is also a world leader among emerging economies in enlightened social safety nets. The best known of these is the Bolsa Familia program. According to the World Bank, which contributes finance to the program, ninety-four percent of the funds reach the poorest 40 percent of the population. Studies prove that most of the money is used to buy food, school supplies, and clothes for the children.

 

Success has sparked adaptations in almost 20 countries—including Chile, Mexico, and other countries around the world, such as Indonesia, South Africa, Turkey, and Morocco. More recently, New York City announced its "Opportunity NYC" conditional transfer of income program, modelled on Bolsa Família and its Mexican equivalent. (Knowledge and good practices can certainly flow in all directions).

 

Now Brazilian colleagues and collaborators have provided evidence of the substantial impact of Bolsa Familia on the incidence rate and mortality from TB. 

 

https://doi.org/10.1038/s41591-024-03381-0

 

Of course, TB and HD are notably different in that HD bacilli have a propensity for nasal mucosa rather than lungs, as well as for nerves/perineural locations in cooler parts of the body. TB spreads despite directly killing people. HD spreads because it does not directly kill people. Nevertheless, the importance of safety nets against extreme poverty is relevant to both diseases.

 

 

 

The World Bank is not concerned only with Brazil and the Bolsa Familia program. Under its President (Ajay Banga, originally from an HD endemic country) it is placing great emphasis on enhancing opportunity in the African continent. An overview of the challenges facing Africa is available in this interview with the WB President. It was done in Abidjan, Ivory Coast, Oct 2024. African leaders from several countries were present.

 

https://youtu.be/T9dI9ZRCZrI?si=fCWa1lp1K9EFGJdx&t=46

 

Health Care is a priority for the World Bank, along with education. The scale of the challenges mean that huge investment is required to beat disease, lack of schooling, lack of jobs and extreme poverty. Several trillion dollars of investment are needed in the coming years. It is in the interests also of the affluent countries to help boost health, schooling and jobs in emerging economies. That is where desperate immigrants originate, and where future customers live.

 

The replenishment of the World Bank's International Development Association (concessional finance provider to the Indian Leprosy Elimination Program from 1993 to the early 2000s) occurs every 3 years. The current replenishment round ends in January 2025. So far the replenishment has been reasonably successful, although much more is needed. This last push for replenishment can make substantial concessional (including free) finance available for health care in the African continent. 

 

The dream of every person at risk of HD can be that the accessible local health facility is capable of reliable services to prevent the visible deformities of HD, and to promote respect for those who experience(d) HD and their families. The training, supplies and supervision can be publicly financed on a scale that is much larger than patchwork efforts. Change is afoot, and it is for us to ride the tide of opportunity so as to stop HD and its adverse consequences.

 

Every citizen of an affluent country can encourage their elected representatives to contribute to the IDA replenishment, which is also able to match and multiply contributions by raising private funds on the bond markets. Jan 2025 is an important month.

 

With all sincerity,

 

Joel Almeida

 

LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

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Friday, January 10, 2025

Fw: Ref.: (LML) Infolep monthly overview of new publications on leprosy. January, 2025.

 

Leprosy Mailing List –  January 10,  2025

 

Ref.:  (LML) Infolep monthly overview of new publications on leprosy. January, 2025.

From:  Roos Geutjes and Sophie Vissers, Amsterdam, the Netherlands

 

Dear colleagues, 

We wish you all the best in 2025—both personally and professionally. Let's make this a year of collaboration, learning, and growth together! 

Many interesting publications are highlighted in this edition to kickstart your new year. Amongst others you can familiarize yourself with:

  • WHO initiative: R&D Blueprint for Neglected Tropical Diseases
  • Effect of Bedaquiline Monotherapy on the improvement in the appearance of skin lesions
  • Clinical efficacy, immunogenicity, and safety of leprosy vaccines in humans
  • PAHO meeting report on interrupting transmission and elimination of leprosy in the Americas

In addition, the podcast from India Today with dr. Agarwal on reaching the communities affected by leprosy in India, is an easy accessible and engaging way to stay informed which you can listen to anytime, anywhere!
 

As we have stepped into the new year, we also want to make sure you don't miss out on any valuable content! If we happened to overlook any publications from last month, feel free to bring them to our attention!

Warm regards,


Roos Geutjes and Sophie Vissers

www.infolep.org
info@infolep.org

Highlighted Publications

An R&D Blueprint for Neglected Tropical Diseases
World Health Organization. 2024.

Bedaquiline Monotherapy for Multibacillary Leprosy
Barreto J, Sammarco Rosa P, Adams L, et al. New England Journal of Medicine. Massachusetts Medical Society. 2024; 391 (23) : 2212-2218.

Individual vulnerability associated with people affected by leprosy in Pernambuco
dos Santos Silva AM, Almeida e Silva RM, Farias Gomes M, et al. Rev Enferm Digit Cuid Promoção Saúde. 2024.

Case detection delay in leprosy: Testing tool reliability and measurement consistency in Ethiopia, Mozambique, and Tanzania.
Mamo E, van Wijk R, Schoenmakers A, et al. PLoS neglected tropical diseases. 2024; 18 (7) : 1-13. 

Effectiveness of ongoing single dose rifampicin post-exposure prophylaxis (SDR-PEP) implementation under routine programme conditions—An observational study in Nepal Banstola NL, Hasker E, Mieras L, et al. PLOS Neglected Tropical Diseases. Public Library of Science (PLoS). 2024; 18 (12) : 1-15.

Meeting for the development of action plans toward the interruption of transmission and elimination of leprosy in the Region of the Americas. Antigua, Guatemala, 9–11 July 2024. Meeting report
Pan American Health Organization , World Health Organization, Americas Region . 2024.

Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability.
Manyazewal T, Davey G, Hanlon C, et al. Nature communications. 2024; 15 (1) : 1-17. 

Efficacy of leprosy vaccines across the globe: A systematic review & meta-analysis of randomized controlled trials.
Dasgupta S, Mukherjee S, Bagchi C, et al. The Indian journal of medical research. 2024; 160 (3&4) : 293-302. 

New publications

Feel free to contact us to receive full-text versions if these cannot be found through the Infolep portal.

Relevance of reporting leprosy related disability at the completion of multi drug therapy: A 5-year retrospective analysis of disability in persons affected by leprosy at ALERT Hospital Ethiopia.
Tegene B, Atnafu T. PLoS neglected tropical diseases. 2024; 18 (12) : 1-20

Progression of the leprosy reaction and nerve damage: A prospective cohort study in children with leprosy from the Brazilian Amazon.
Bandeira S, Anjos A, Pires C, et al. PLoS neglected tropical diseases. 2024; 18 (12) : 1-15. 

Access and utilisation of leprosy healthcare services in high-burden districts in Ethiopia
Marrye SS, Shakwane S. Southern African Journal of Infectious Diseases. AOSIS. 2024; 39 (1) : 1-9. 

Measuring social vulnerability in communities and its association with leprosy burden through spatial intelligence in central West Brazil to guide strategic actions
Júnior JFM, Ramos ACV, Alves JD, et al. Archives of Public Health. Springer Science and Business Media LLC. 2024; 82 (1) : 1-9.

Implementation of different Control Strategies for leprosy individuals considering Quality of Life (QoL) with associated Cost-Effectiveness Analysis (CEA)
Mondal T, Ghosh S, Mukherjee S, et al. Nonlinear Science. Elsevier BV. 2024.

IgG seroprevalence of Toxoplasma gondii and Leishmania infantum in leprosy patients: Implications for screening and management of co-infections.
de Oliveira A, Brito R, Siqueira W, et al. Diagnostic microbiology and infectious disease. 2024.

Electrochemical magneto-immunoassay based on Mycobacterium leprae mimotope for serological diagnosis of leprosy
de Almeida SV, da Silva PRL, Fonseca WT, et al. Biosensors and Bioelectronics. Elsevier BV. 2024.

Integrating Community Engagement in Zero Leprosy Efforts: A Pathway to Sustainable Early Detection, Control and Elimination
Fastenau A, Willis M, Vettel C, et al. Tropical Medicine and Infectious Disease. MDPI AG. 2024; 9 (12) : 1-5.

Trend and Factors Associated with Medical-Surgical Complications in Patients Discharged from Leprosy Multidrug Therapy at the Specialized Regional Hospital in Macenta, Guinea, from 2012 to 2021.
Hébélamou J, Grovogui F, Manet H, et al. Tropical medicine and infectious disease. 2024; 9 (12) : 1-9. 

Tecnologias educacionais em hanseníase na atenção primária à saúde
Souza APDC, Araújo ODD. Revista Eletrônica Acervo Científico. Revista Eletronica Acervo Saude. 2024.

Infecção pelo Mycobacterium leprae em pacientes com psoríase vulgar: uma revisão da literatura
Coimbra BZ, Dias LR, Soriano BFM, et al. Journal Archives of Health. Brazilian Journals. 2024; 5 (6) : 1-13. 

Profils sociodémographiques des personnes vivant avec des infirmités liées à la lèpre au Kongo Central, République Démocratique du Cong
Bavenga Bavenga C, Ghoma Linguissi LS. Annales Africaines de Médecine . 2024

Panorama da hanseníase em Mato Grosso: aspectos epidemiológicos e distribuição geográfica dos casos em menores de 15 anos
Silva GCC, Souza BAE, Martins GB, et al. COORTE - Revista Científica do Hospital Santa Rosa. COORTE - REVISTA CIENTIFICA DO HOSPITAL SANTA ROSA. 2024; 18 (18) : 75-89. 

Community-based psychosocial support interventions to reduce stigma and improve mental health of people with infectious diseases: a scoping review.
Anindhita M, Haniifah M, Putri A, et al. Infectious diseases of poverty. 2024; 13 (1) : 1-17. 

Transcriptome immune-regulatory differences between leprosy patients and type 1 reaction patients, before onset of symptoms
Correa-Macedo W, Dallmann-Sauer M, Orlova M, et al. PLOS Neglected Tropical Diseases. Public Library of Science (PLoS). 2024; 18 (12) : 1-30. 

Assessment of the Degree of Neurofunctional Disability in Leprosy Patients in a Municipality in Bahia, Brazil 
Costa HB, Braga IO, Silva VSD, et al. Medicina (Ribeirão Preto). Universidade de São Paulo. Agência de Bibliotecas e Coleções Digitais. 2024; 57 (1): 1-14. 

A retrospective cohort study of monthly rifampicin, ofloxacin and minocycline in the management of leprosy at the Hospital for Tropical Diseases, London, United Kingdom
Sivakumaran P, Barros BD, Antonio Dias VL, et al. PLOS Neglected Tropical Diseases. Public Library of Science (PLoS). 2024; 18 (12) : 1-10.

Meanings and senses of Hansen's disease for health workers from a Vygotskian perspective: a qualitative study.
Santos K, Gonçalves M, Santos F, et al. BMC health services research. 2024; 24 (1) : 1-11. 

The landscape of chemokine and cytokine is associated with the distinct clinical status of leprosy patients and their respective household contacts
Pereira de Oliveira LB, Marçal PHF, Campos KD, et al. Frontiers in Immunology. Frontiers Media SA. 2024.

Natural Product-Based Treatment for Leprosy
Padhy I, Patro G, Panda M. Natural Products for Antibacterial Drug Development: Recent Advancement of Computational Approach. Springer Nature Singapore. 2024.

Communication Dynamics and Elite Perceptions: Assessing Government Policy Effectiveness in Sumberglagah Leprosy Village, Indonesia 
Hidayat E, Susilo D, Ansyah RHA, et al. Nyimak: Journal of Communication. 2024. 283 - 298.

Rapid test for Mycobacterium leprae infection: a practical tool for leprosy.
Pierneef L, van Hooij A, de Jong D, et al. Infectious diseases of poverty. 2024; 13 (1) : 88. 

Nasal Endoscopic Findings of Leprosy Patients in Three Rural Areas in Indonesia
Supartono N, Wardani RS, Endiyarti F, et al. Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology). Japan Rhinologic Society. 2024; 63 (4) : 463-470. 

Contribuições de uma Liga Acadêmia Multidisciplinar sobre Doenças Tropicais Negligenciadas: Relato de Experiência
De Sousa Araujo LB, Francisca Victória Vasconcelos Sousa , Khaab Gibran Leal Vasconcelos , et al. SANARE - Revista de Políticas Públicas. Escola de Saude Publica Visconde Saboia. 2025; 23 (2) : 147-153. 

Podcast Educacional sobre Hanseníase como Recurso de Aprendizagem
Ferreira MC, Costa RHGD, Muniz RAA, et al. Cogitare Enfermagem. FapUNIFESP (SciELO). 2024.

Hanseníase em menores de 15 anos de idade na Amazônia: epidemiologia, vigilância e desafios no estado do Pará, Brasil
Giordano MPDL, Carneiro FRO. Revista Pan-Amazônica de Saúde. Instituto Evandro Chagas. 2024.

Case Reports

Tofacitinib in Leprosy: A Novel Therapeutic Approach in Chronic Recalcitrant Type II Reactions.
Suresh B, Reshmi P, Jaipal J, et al. Cureus. 2024; 16 (11) : 1-5. 

Cryptococcosis involving skin and bone in a non‐HIV lepromatous leprosy patient with chronic type 2 lepra reaction
Chhabra N, Peethambaran AS, Kar BK, et al. International Journal of Dermatology. Wiley. 2024.

The Forgotten Infection Cases: Leprosy Disease Oral Manifestations and Its Problem
Nurfianti , Sasanti H, Tri Wulandari EA, et al. Journal of Indonesian Dental Association. 2024.

Lucio's phenomenon in a non-endemic region: A case report
Yu AC, Chan AR, Chow EY. SAGE Open Medical Case Reports. SAGE Publications. 2024.

A Case of Lepromatous Leprosy Presenting With Multiple Morphologies in Philadelphia
O'Brien MA, Hyde J, Hsu S. Cureus. Springer Science and Business Media LLC. 2024.

An alternative multidrug regimen for multibacillary Hansen's disease: a case report.
Akhverdyan N, Cantor Z, Hawkins K. Journal of medical case reports. 2024; 18 (1) : 1-4. 

Case Report: Acute Additive Polyarthritis as a Presentation of Type 2 Lepromatous Reaction: The Role of Differential Diagnosis
Pérez Mingan GC, Llamas Castellanos BC, Álvarez Lora EDC, et al. International Journal of Rheumatic Diseases. Wiley. 2024.

Borderline Lepromatous Leprosy With Type 1 Reaction: A Challenging Diagnostic Case
Saray PLA, Dalit ZF, Itzel FBC, et al. Clinical Case Reports. Wiley. 2024; 12 (12) : 1-5. 

Nervous leprosy revealed after treating atopic eczema
Dicko AA, Cissé L, Traore A, et al. Our Dermatol Online. 2025.

Glomerulonefrite Rapidamente Progressiva (GNRP) pós-infecciosa em um paciente com diagnóstico de hanseníase: Relato de caso
Martins MP, Jorge MCCR, Almeida WS. Research, Society and Development. Research, Society and Development. 2024; 13 (12) : 1-9.

News & Events

Ethiopia strengthens leprosy case finding to bolster early diagnosis (WHO Afro)

Call for Funding (Global Health Innovative Technology Fund)

Call for Action: Help the WHO to identify the R&D priorities for neglected tropical diseases
(World Health Organization)

Second global meeting on skin-related neglected tropical diseases (skin NTDs) 
March 24-26, 2025; hybrid; Geneva, Switzerland 
The WHO held its first global meeting on skin-related neglected tropical diseases (skin NTDs) on 27–31 March 2023 in Geneva, Switzerland. This meeting has built the foundation and momentum for the second global meeting to be held on 24–26 March 2025. The event demonstrates the collective commitment of the global skin-NTD community to achieving a key objective of the NTD road map: integration. 

Conference on Neglected Tropical Diseases 2024
May 16, 2025; hybrid; Nairobi, Kenya.
The 1st edition of the Conference on NTDs, organized by AME is a hybrid meeting. The abstract-driven conference proposes a platform to disseminate new advancements, real-world data, implementation challenges, and novel governing models to discuss and generate solutions for cross-cutting topics and ultimately reduce the disease burden and societal impact of NTDs. Registration is open.

European Congress for Tropical Medicine and International Health 2025
September 29-October 2, 2025, Hamburg
Save the Date! ECTMIH 2025 is currently still in the planning stage. All information is expected to be available from January 2025 and registration will be possible from then on.

Call for proposals: Research capacity strengthening grant (Leprosy Research Initiative)

Call for Proposals: RESILIENTD grant (Leprosy Research Initiative , Foundation Anesvad)

Tropical Infectious Diseases Gordon Research Conference
February 2-7, 2024; Renaissance Tuscany Il Ciocco, Lucca, Italy
The theme of the conference is "Basic and Clinical Research Strategies for Tackling Tropical Infectious Diseases in a Globalized World". Registration is closed.

Global Disability Summit 2025 
April 2-4, 2025; Berlin, Germany. 
The Global Disability Summit aims to galvanize global efforts to realize disability inclusion around the world. It is a mechanism bringing together a wide variety of high-level stakeholders, engaging and discussing the progress in disability inclusion: governments, multilateral agencies, the private sector, academia and civil society organizations, organizations of persons with disabilities, and foundations. Registration is open.

The Twelfth EDCTP Forum
June 15-20, 2025; Kigali Convention Centre, Kigali, Rwanda
The theme for the 2025 Forum is "Better health through global research partnerships". Registration is open.

22nd International Leprosy Congress 
July 5-9, 2025; Bali Nusa Dua Convention Centra (BNDCC), Bali, Indonesia 
This year the 22nd International Leprosy Congress (ILC) will be held in Bali, Indonesia! The congress uphold the theme: "Towards a World with Zero Leprosy". The theme aims to enhance the evidence into the clinical care in leprosy early diagnosis and therapeutics in the global era and prepare to face the new perspective of dermatology practice. The deadline of abstract submission is 28th of February and the deadline for late registration is July the 6th.

Links

Info Hansen - A innovative hub for knowledge sharing about Hansen's Disease
 

ALLF - Official website of the Association des Léprologues de Langue Française
 

LML - Leprosy Mailing List - a free moderated email list that allows all persons interested in leprosy to share ideas, information, experiences and questions
 

InfoNTD - Information on cross-cutting issues in Neglected Tropical Diseases (NTDs)

ILEP newsletter archive

GPZL newsletter subscription

WHO Goodwill Ambassador's Leprosy Bulletin

Leprosy Review

Leprosy Review Repository (1928-2001)

Fontilles Revista de Leprología

Indian Journal of Leprosy

Hansenologia Internationalis

HARP - database of Hansen's Disease Antimicrobial Resistance Profiles

GDPR & the Infolep newsletter

 
New EU data protection regulations came into force on 25 May 2018. We have been reviewing our practices with regards to the GDPR, including our privacy statement and mailing list.

Infolep sends out monthly e-mails with an overview of recent publications on leprosy and related issues. The purpose of this activity is to keep subscribers up to date.

Infolep will only process the data we have (names, email addresses) for the purpose of sending you the newsletter. We take your security seriously and will never share your contact details with anyone else.

You can update your preferences or unsubscribe from this list at any time.

LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

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