Leprosy Mailing List – November 9, 2024
Ref.: (LML) Infolep monthly overview of new publications on leprosy. November 2024.
From: Roos Geutjes and Upasana Regmi, Amsterdam, the Netherlands
Dear colleagues,
This month, we're excited to share that American Leprosy Missions has announced the start of a Phase 1b clinical trial for LepVax, the first vaccine developed specifically for leprosy. The goal of this trial is to demonstrate vaccine safety and immune response in healthy individuals in a leprosy-endemic area of Brazil. For more details on this milestone and other news, check the 'News and Events' section at the bottom of this overview.
In this issue, you'll find a wealth of valuable resources:
- Research highlights: Discover studies addressing disability and quality of life among leprosy patients in India, Tanzania, and Guinea, as well as innovative drug delivery approaches and recent findings on biomarkers predicting leprosy reactions.
- Global updates: This includes new WHO insights into progress on the 2030 elimination targets, paired with commentary from Dr. Paul Saunderson on tackling the challenges ahead.
- Engaging articles: From community engagement techniques to social behavior change materials, there's plenty for field teams to explore and apply.
- Unique case reports: Featuring rare clinical presentations and lessons learned.
As always, we encourage you to explore the latest research and resources on Infolep and InfoNTD to stay informed and engaged.
Warm regards,
Roos Geutjes and Upasana Regmi
www.infolep.org
info@infolep.org
Highlighted Publications
Impact of climate change on the rights of people affected by leprosy-related disability: a human rights approach
Ahmed A. African Journal of Law, Ethics and Education. 2024.
Global leprosy (Hansen disease) update, 2023: Elimination of leprosy disease is possible – Time to act!
World Health Organization. 2024.
Measuring the quality of life of people with severe leprosy and lymphatic filariasis disability in India using an informal, intervention-focused, contextual, and integrated tool for NTD disability
Anand S, Kant Singh R, John A, et al. Leprosy Review. Lepra. 2024; 95 (3): 1-15.
Burden of leprosy and associated risk factors for disabilities in Tanzania from 2017 to 2020
Mrema G, Hussein A, Magoge W, et al. PLOS ONE. Public Library of Science (PLoS). 2024; 19 (10): 1-13.
Frequency and Factors Associated with Disabilities among Leprosy Patients Admitted to the Kindia Disability Prevention and Physical Rehabilitation Centre (Pirp) in Guinea from 2017 to 2021
Ibrahima Sory SS, Sidikiba S, Delphin K, et al. Tropical Medicine and Infectious Disease. MDPI AG. 2024; 9 (10): 1-9.
Risk Factors for Psychological Impact and Stigma Among Leprosy Patients: A Systematic Review
Rasyidi N, Yusuf A, Tristiana D. Indonesian Journal of Global Health Research. 2024.
Ecuador Towards Zero Leprosy: A Twenty-Three-Year Retrospective Epidemiologic and Spatiotemporal Analysis of Leprosy in Ecuador
Hernandez-Bojorge S, Gardellini T, Parikh J, et al. Tropical Medicine and Infectious Disease. MDPI AG. 2024; 9 (10): 1-18.
Leprosy-related disability in children and adolescents under 15 years old in Brazil: evaluation of macro-regional disparities from 2001 to 2022
Barbosa-Lima R, Vivian GF, Pinto MC, et al. Journal of Health & Biological Sciences. Instituto para o Desenvolvimento da Educacao. 2024; 12 (1): 1-8.
Knowledge, Attitudes, and Practices of Barangay Health Workers in Marawi City regarding Hansen's Disease.
Pandapatan A, Dofitas B, Gervasio M, et al. Acta medica Philippina. 2024; 58 (17): 8-16.
New publications
Feel free to contact us to receive full-text versions if these cannot be found through the Infolep portal.
Communication Dynamics and Elite Perceptions: Assessing Government Policy Effectiveness in Sumberglagah Leprosy Village, Indonesia
Hidayat E, Susilo D, Ansyah RHA, et al. Nyimak: Journal of Communication. 2024
Clinically Suspicious Cases of Hansen's Disease at a Tertiary Care Hospital in South India: A Clinicopathological Study
Shabnam A, Dennis Joseph L, Priyathersini N, et al. Cureus. Springer Science and Business Media LLC. 2024.
Profile of Leprosy Patients at the Dermatology and Venereology Polyclinic of Dr. M. Djamil Padang Hospital in 2018-2021
Habib El Binampiy Busnia , Gustia Rina , Deddy Herman. International Journal of Health and Medicine. Asosiasi Penelitian dan Pengajar Ilmu Hukum Indonesia. 2024; 1 (4): 120-133.
Hubungan Dukungan Keluarga dengan Harga Diri Pada Pasien Kusta di Klinik Kulit dan Kelamin RSUD dr. Saiful Anwar Malang
Suhermin Y. Jurnal Keperawatan Muhammadiyah. 2024.
Cystic Subcutaneous Phaeohyphomycosis Caused by Cladophialophora Species in an Elderly Leprosy Patient
Kumar PBP, Mala M, Jacob ES. Cureus. Springer Science and Business Media LLC. 2024.
IL-22 in Mycobacterium leprae-induced Nerve injury.
Geng H, Bao F, Wang C, et al. The British journal of dermatology. 2024.
Severity Classification of Electronic Health Records of Leprosy Patients Using Chicken Swarm Optimization-based LSTM Model
Mehta J, Kumar A, Chakrabarti P. Library Progress International. 2024.
Th17 and T Regulatory Cytokines in Serum, Lesional Skin, and Stimulated Peripheral Blood Mononuclear Cell Culture Supernatants from Type 1 Leprosy Reaction Patients.
Dabas S, Khurana A, Singh I, et al. The American journal of tropical medicine and hygiene. 2024.
Análise dos casos de hanseníase no estado do Pará entre 2001 e 2020
Alves Silva LE, Lima da Silva E, Borges da Silva DM, et al. Revista de Epidemiologia e Controle de Infecção. APESC - Associacao Pro-Ensino em Santa Cruz do Sul. 2024; 14 (2): 1-7.
Aspectos diagnósticos e terapêuticos da hanseníase
Felix gonçalves E, Bronzeado Cavalcanti Coutinho L, Clara Fernandes Diógenes A, et al. Imunologia e Doenças Infecciosas e Parasitárias - Edição I. Guilherme Barroso L. De Freitas. 2024.
Hanseníase e avaliação neurológica simplificada: conhecimento de profissionais da atenção primária à saúde
Freitas Maia AC, Tronconi IC, Sabeh ACB, et al. Revista Colombiana de Enfermería. Universidad el Bosque. 2024; 23 (1): 1-14.
Impacto clínico das internações por sequelas de Hanseníase: uma análise epidemiológica abrangente
Igarashi ÁT, Gonzaga PDV, Lana SC, et al. Brazilian Journal of Health Review. South Florida Publishing LLC. 2024; 7 (5): 1-10.
Avaliação do grau de incapacidade neurofuncional dos pacientes com diagnóstico de Hanseníase
Oliveira PDS, Silva AMFD, Neto LRDS, et al. Brazilian Journal of Health Review. South Florida Publishing LLC. 2021; 4 (4): 15870-15887.
Fatores associados à percepção de estigma entre pacientes com hanseníase
Guedes TRDMT. Universidade de São Paulo. Agência de Bibliotecas e Coleções Digitais. 2024.
A assistência de enfermagem aos portadores de hanseníase assistidos pela atenção primária: revisão integrativa
Oliveira DFD, Abreu JED, Oliveira GS, et al. Revista Ibero-Americana de Humanidades, Ciências e Educação. Revista Ibero-Americana de Humanidades, Ciencias e Educacao. 2024; 10 (6): 2024-2034.
Perfil epidemiológico dos casos de hanseníase no município de tucuruí- pa entre 2018 e 2022
Cruz DAV, Corrêa DCA, Pinheiro CJB, et al. Revista Contemporânea. South Florida Publishing LLC. 2024; 4 (10): 1-20.
Sobreposição da hanseníase em redes de convívio domiciliar: gerações envolvidas, densidade de casos e perfis sociodemográfico e econômico em municípios do Norte e Nordeste do Brasil
Boigny RN, Souza EAD, Reis ADSD, et al. Cadernos Saúde Coletiva. FapUNIFESP (SciELO). 2024; 32 (1): 1-15.
Integração de ações de vigilância, prevenção e controle de doenças tropicais negligenciadas no SUS: perspectivas epidemiológicas e operacionais para Hanseníase e Doença de Chagas no sudoeste do estado da Bahia
García GSM. Faculdade de Medicina, Universidade Federal do Ceará. 2024.
Assessment of the Degree of Neurofunctional Disability in Leprosy Patients in a Municipality in Bahia, Brazil
Costa HB, Braga IO, Silva VSD, et al. Medicina (Ribeirão Preto). Universidade de São Paulo. Agência de Bibliotecas e Coleções Digitais. 2024; 57 (1): 1-14.
Unveiling inflammatory biomarkers in multibacillary leprosy: the role of lymphocyte-platelet ratio in predicting leprosy reactions
Trindade LC, da Paz AR, da Silveira Mendes M, et al. Archives of Dermatological Research. Springer Science and Business Media LLC. 2024.
Exploring the dynamics of leprosy transmission with treatment through a fractal–fractional differential model
Kubra KT, Ali R, Ujala B, et al. Partial Differential Equations in Applied Mathematics. Elsevier BV. 2024.
A Clinico‐Pathological Study and Bacteriological Study of Leprosy Cases in a Tertiary Care Hospital
Sunitha A, Deshpande N, Ramya C, et al. Research Journal of Medical Sciences. 2024.
Streptococcus dysgalactiae subsp.-equisimilis as an emerging secondary pathogen in leprosy foot ulcers
Ebineshan K, Pallapati M, Srikantam A. Iranian Journal of Microbiology. 2024.
One-Pot Synthesis and Characterization of Dapsone-Loaded Zeolitic Imidazolate Framework-8
Diniz JMCT, Martins JC, de Melo Amaral IM, et al. Journal of Cluster Science. Springer Science and Business Media LLC. 2024.
Temporal trends and spatial analysis of leprosy surveillance indicators in the municipalities of the state of Mato Grosso, 2008-2022
Freitas LRSD, Duarte EC. Revista da Sociedade Brasileira de Medicina Tropical. FapUNIFESP (SciELO). 2024.
Comparison of the clinical manifestations and histopathological results in leprosy: A 5-year retrospective study in a tertiary hospital
Sari ARP, Siswati AS, Ferronika P, et al. Leprosy Review. Lepra. 2024; 95 (4): 1-7.
A Contemporary Cross-Sectional Study on Oral Manifestations of Leprosy
Thangavel G, Sabarinathan S, Annamalai S, et al. Journal of Communicable Diseases. Advanced Research Publications. 2024; 56 (3): 1-4.
Epidemiología y clínica de los pacientes con lepra en un centro de referencia de Paraguay
Re Domínguez ML, Olmedo OMA. Revista del Nacional (Itauguá). Instituto de Investigaciones en Ciencias de la Salud. 2024; 16 (3): 1-13.
Hanseníase: muito além da pele – o impacto sistêmico e psicológico no paciente com a doença
Zanuto T, Amália Santos Schiochet Pontes , Evelyn Thamara de Almeida Fortunato , et al. Brazilian Journal of Implantology and Health Sciences. Brazilian Journal of Implantology and Health Sciences. 2024; 6 (10): 1092-1104.
Análise epidemiológica da hanseníase na região sudeste do brasil
Bahia VGL, Pereira AAF, Neto JFDO, et al. Brazilian Journal of Implantology and Health Sciences. Brazilian Journal of Implantology and Health Sciences. 2024; 6 (10): 2719-2731.
Incapacidades na hanseníase: uma revisão da literatura
Fadel SR, Marques BG, Cajado JB, et al. Open Science Research XVI. Editora Científica Digital. 2024.
Hanseníase em indígenas do estado do Tocantins: perfil de casos e análise de tendência, 2001-2022
Almeida MCC, Martins NP, Monteiro GG, et al. Revista Eletrônica Acervo Saúde. Revista Eletronica Acervo Saude. 2024; 24 (10): 1-10.
O tempo de diagnóstico da hanseníase em correlação com o grau de incapacidade: uma coorte de 5 anos em Campos dos Goytacazes
Camara Jacyntho S, Carvalho Ulrick Dib J, Pellegrini Nahn Junior E. Anais da Semana Científica da Faculdade de Medicina de Campos. Faculdade de Medicina de Campos. 2024.
Perfil epidemiológico da hanseníase em crianças e adolescentes menores de quinze anos no estado de sergipe: análise de dados entre 2012 e 2022
Guimarães CV. Revista Contemporânea. South Florida Publishing LLC. 2024; 4 (10): 1-16.
Clusters de alto risco dos casos por Hanseníase na região Nordeste do Brasil: Modelagem espaço-temporal retrospectiva e prospectiva
Clemente GS, Almeida DHD. Research, Society and Development. Research, Society and Development. 2024; 13 (10): 1-14.
Leprosy/Hanseníase: An Interdisciplinary and Epidemiological Analysis Amazônia Paraense -Vila Santo Antônio do Prata-PA.
de Alcantara MDLB, Corbett CE, Brasil M. International Journal of Research and Scientific Innovation. RSIS International. 2024; XI (XV) : 334-355.
Case Reports
Unveiling the clinico-dermoscopic and histopathological correlation of histoid leprosy: A case series
Meda S, Bonthu I, Seeram R, et al. Leprosy Review. Lepra. 2024; 95 (3): 1-12.
Lepra: enfermedad reemergente
Hincapie DAF, Rozo EFM, Agudelo LG, et al. Dermatology Mexican Megazine. 2024
Ulcerative type 1 lepra reaction in borderline-tuberculoid leprosy
Mushtaq S. Hansenologia Internationalis: hanseníase e outras doenças infecciosas. Instituto Lauro de Souza Lima. 2024.
Diagnostic Enigma in a rare Case of Primary Neuritic Leprosy
Ahmed S, Rahman A, Ahmed T, et al. Bangladesh Journal of Medicine. Bangladesh Academy of Sciences. 2024; 35 (3) : 214-217.
Immune-Mediated Glomerulonephritis as Type 2 Lepra Reaction Posttreatment of Lepromatous Leprosy: A Case Report.
Kantak D, Dsouza M. Indian journal of nephrology. 2024; 34 (5): 520-521.
The First Case Report of Pulmonary Hypertension in Leprosy
Siregar M, Wahidji V. Iranian Heart Journal. 2024.
Erythema nodosum leprosum: condition developed by non-adherence
Gladwin E, Patel M, Mistry M. International Journal of Pharmacy and Pharmaceutical Sciences. Innovare Academic Sciences Pvt Ltd. 2024.
Erythematous lesions with Woronoff's ring like perilesional hypopigmented halo in a case of leprosy
Mushtaq S. Hansenologia Internationalis: hanseníase e outras doenças infecciosas. Instituto Lauro de Souza Lima. 2024.
Diffuse Lepromatous Leprosy with Lucio PhenomenonCaused by Mycobacterium leprae
Kumalasari DN, Hendaria MP, Dewi AWK, et al. Journal of Mycology and Infection. Korean Society for Medical Mycology. 2024.
Clinico-histological correlation of Hansen's disease at tertiary care centre
Rishi P, Patel A, Shrivastava P, et al. Journal of Cardiovascular Disease Research. 2024.
A Case of Anatopic Phenomenon in Dapsone Hypersensitivity Syndrome
Devi S. K, Raviprakash D, Priyadarshini A, et al. Cureus. Springer Science and Business Media LLC. 2024.
Analyzing the Vulnerability of Children of Recovered Leprosy Patients: A Case Study of a Leprosy Village in Vietnam
Watanabe H, Vu Tuan Anh, Huynh Cong Ai, et al. JAPANESE JOURNAL OF LEPROSY. Japanese Leprosy Association. 2024; 93 (2): 39-47.
Robust contact tracing and screening needed for leprosy control and protection of vulnerable children
Pilaka K, Pallapati M, Jaladi Z, et al. The Iranian Journal of Microbiology. 2024.
Cystic Subcutaneous Phaeohyphomycosis Caused by Cladophialophora Species in an Elderly Leprosy Patient
Kumar PBP, Mala M, Jacob E. Cureus. 2024
Lepromatous leprosy with respiratory failure in the City of Buenos Aires.
Villa R. Medicina. 2024; 84 (5): 1042-1043.
Erythema nodosum leprosum as the initial presentation of lepromatous leprosy.
Hingtgen G, Mojica R, Beatty N, et al. JAAD case reports. 2024.
Eritema nodoso centrofacial com apresentação semelhante a furúnculo em paciente de município da pré-amazônia maranhense
Cruz DDSD, Barroso PMA, Silva TM, et al. Brazilian Journal of Health Review. South Florida Publishing LLC. 2024; 7 (5): 1-7.
Análise integrada da hanseníase em um município hiperendêmico do Brasil
Moreno FC, Medrado JJDS, Oliveira KAD, et al. CONTRIBUCIONES A LAS CIENCIAS SOCIALES. South Florida Publishing LLC. 2024; 17 (10): 1-20.
Os desafios e dificuldades enfrentadas por portadores de hanseníase durante a pandemia da COVID-19
Matos MOP, Anjos AAD, Macedo CG, et al. Revista Eletrônica Acervo Saúde. Revista Eletronica Acervo Saude. 2024; 24 (10): 1-13.
Reação adversa grave à dapsona no tratamento da hanseníase
Rodrigues MEG, Costa JEFD, Palitot EB. Hansenologia Internationalis: hanseníase e outras doenças infecciosas. Instituto Lauro de Souza Lima. 2024
News & Events
Anvisa authorizes testing of the first vaccine against leprosy in Brazil (The Impartial)
Indonesia launches final push to eliminate lymphatic filariasis, leprosy and yaws (World Health Organization)
Global leprosy (Hansen disease) update 2023: Elimination of leprosy disease is possible – Time to act! Commentary: Dr Paul Saunderson (International Federation of Anti-Leprosy Associations)
Stigma and mental wellbeing in relation to skin NTDs
November 14, 2024, 13:00 CET
This WHO Skin-NTDs webinar will focus on stigma and mental wellbeing in relation to skin NTDs.
Lepra launches its ambitious new 2024 - 2030 Global Strategy
November 20, 2024, 19:00 GMT
Join Lepra's special online premiere event to learn more about their new global strategy focused on "Health, Inclusion, and Innovation." This event will provide an in-depth look at how Lepra's innovative and inclusive approach empowers communities, builds resilience, and ensures sustainable care for those affected by leprosy and lymphatic filariasis.
Second global meeting on skin-related neglected tropical diseases (skin NTDs)
Save the date! March 24-26, 2025
The World Health Organization (WHO) held its first global meeting on skin-related neglected tropical diseases (skin NTDs) on 27–31 March 2023 in Geneva, Switzerland. This meeting has built the foundation and momentum for the second global meeting to be held on 24–26 March 2025. The event demonstrates the collective commitment of the global skin-NTD community to achieving a key objective of the NTD road map: integration.
Conference on Neglected Tropical Diseases 2024
May 2025; Nairobi, Kenya.
The 1st edition of the Conference on Neglected Tropical Diseases, organized by AME is tentatively scheduled in May 2025 in Nairobi, Kenya, as a hybrid meeting. The abstract-driven conference proposes a platform to disseminate new advancements, real-world data, implementation challenges, and novel governing models to discuss and generate solutions for cross-cutting topics and ultimately reduce the disease burden and societal impact of NTDs. This proposal supports the progress in foundational pillars of the WHO Roadmap by facilitating evidence-based program implementation, leveraging the cross-cutting approach, and providing a forum to discuss a paradigm shift toward country ownership of elimination programs.
Call for Proposals: RFA: Reaching the last mile: Addressing barriers to the implementation of the NTD interventions among Mobile and Migrant Populations (MMP) Coalition for Operational Research Neglected Tropical Diseases)
Ivory Coast: Progress in a collective commitment towards "Zero Leprosy" by 2030 (Raoul Follereau)
How do we shift the dial on some of leprosy's biggest and most stubborn problems? (The Leprosy Mission)
Addressing Social Determinants of Health to Accelerate Disease Elimination
November 14, 2024, 9:30-11:15 EST
This webinar will explore tools and approaches to incorporate social determinants into programmatic actions to address health equity and increase effectiveness of activities, drawing from regional experiences and innovative frameworks.
Call for Proposals: Mental Health Award - Accelerating scalable digital mental health interventions
This call will fund research to evaluate and further develop scalable digital interventions to advance early intervention in depression, anxiety and psychosis. Funding amount: £3 to 7 million per project. The application must be submitted by 17:00 GMT on the 5th of December 2024.
Tropical Infectious Diseases Gordon Research Conference
February 2-7, 2024; Renaissance Tuscany Il Ciocco, Lucca, Italy
The theme of the conference is "Basic and Clinical Research Strategies for Tackling Tropical Infectious Diseases in a Globalized World". Registration is open and deadline is January 5, 2025.
Global Disability Summit 2025
April 2-4, 2025; Berlin, Germany.
The Global Disability Summit aims to galvanize global efforts to realize disability inclusion around the world. It is a mechanism bringing together a wide variety of high-level stakeholders, engaging and discussing the progress in disability inclusion: governments, multilateral agencies, the private sector, academia and civil society organizations, organizations of persons with disabilities, and foundations.
22nd International Leprosy Congress (ILC)
July 5-9, 2025; Bali Nusa Dua Convention Centra (BNDCC), Bali, Indonesia
This year the 22nd International Leprosy Congress (ILC) will be held in Bali, Indonesia! The congress uphold the theme: "Towards a World with Zero Leprosy". The theme aims to enhance the evidence into the clinical care in leprosy early diagnosis and therapeutics in the global era and prepare to face the new perspective of dermatology practice. Abstract submission and early bird registration is open until November 30th.
Links
Info Hansen - A innovative hub for knowledge sharing about Hansen's Disease
ALLF - Official website of the Association des Léprologues de Langue Française
LML - Leprosy Mailing List - a free moderated email list that allows all persons interested in leprosy to share ideas, information, experiences and questions
InfoNTD - Information on cross-cutting issues in Neglected Tropical Diseases (NTDs)
ILEP newsletter archive
GPZL newsletter subscription
WHO Goodwill Ambassador's Leprosy Bulletin
Leprosy Review
Leprosy Review Repository (1928-2001)
Fontilles Revista de Leprología
Indian Journal of Leprosy
Hansenologia Internationalis
HARP - database of Hansen's Disease Antimicrobial Resistance Profiles
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