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Assessing the feasibility of integration of self-care for filarial lymphoedema into existing community leprosy self-help groups in Nepal.
Pryce J, Mableson HE, Choudhary R, et al. BMC Public Health. 2018; 18(1):201.
Abstract Lymphatic filariasis (LF) and leprosy are disabling infectious diseases endemic in Nepal. LF infection can lead to lymphoedema and hydrocoele, while secondary effects of leprosy infection include impairments to hands, eyes and feet. The disabling effects of both conditions can be managed through self-care and the supportive effects of self-help groups (SHGs). The aim of this study was to determine the feasibility of integrating LF affected people into existing leprosy SHGs in Nepal.
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Perceived causes and risk factors of Buruli ulcer among patients at Agogo Presbyterian hospital in Ashanti Region of Ghana.
Anokye R, Acheampong E, Mprah WK, et al. BMC Res Notes. 2018; 11(1):64.
Abstract The incidence of Buruli ulcer has been recorded in about 30 countries globally and Africa seems to be the most affected area. The study sought to determine perceived causes and risk factors of Buruli ulcer among patients who visit the Agogo hospital in Asante-Akim North District in the Ashanti region of Ghana. A descriptive study design was adopted using a simple random sampling technique to select 400 patients attending The Presbyterian Hospital at Agogo.
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Combined effectiveness of anthelmintic chemotherapy and WASH among HIV-infected adults.
Means AR, van Lieshout L, Brienen E, et al. PLoS Negl Trop Dis. 2018; 12(1):e0005955.
Abstract Current global helminth control guidelines focus on regular deworming of targeted populations for morbidity control. However, water, sanitation, and hygiene (WASH) interventions may also be important for reducing helminth transmission. We evaluated the impact of different potential helminth protective packages on infection prevalence, including repeated treatment with albendazole and praziquantel with and without WASH access.
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Sanitation and water supply coverage thresholds associated with active trachoma: Modeling cross-sectional data from 13 countries.
Garn JV, Boisson S, Willis R, et al. PLoS Negl Trop Dis. 2018; 12(1):e0006110.
Abstract Facial cleanliness and sanitation are postulated to reduce trachoma transmission, but there are no previous data on community-level herd protection thresholds. We characterize associations between active trachoma, access to improved sanitation facilities, and access to improved water sources for the purpose of face washing, with the aim of estimating community-level or herd protection thresholds.
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"Cross-border collaboration in onchocerciasis elimination in Uganda: progress, challenges and opportunities from 2008 to 2013."
Lakwo T, Ukety T, Bakajika D, et al. Global Health. 2018; 14:16.
Abstract Until recently onchocerciasis was prevalent in 37 out of 112 districts of Uganda with at least 3.8 million people at risk of contracting the disease, but following the launching of community-directed treatment with ivermectin (CDTI) in 1996 and the adoption of an onchocerciasis elimination policy in 2007, the country has made significant progress in combating the disease. This paper summarises the experience of Uganda in addressing cross-border issues on onchocerciasis elimination with DRC.
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Economic evaluations of lymphatic filariasis interventions: a systematic review and research needs.
Gedge LM, Bettis AA, Bradley MH, et al. Parasit Vectors. 2018; 11(1):75.
Abstract In 2000, the World Health Organization established the Global Programme to Eliminate Lymphatic Filariasis (GPELF), with the goal of eliminating the disease as a public health problem by 2020. Since the start of the programme, a cumulative total of 6.2 billion treatments have been delivered to affected populations - with more than 556 million people treated in 2015 alone. In this paper, we perform a rigorous systematic review of the economic evaluations of lymphatic filariasis interventions have been conducted.
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Elimination of lymphatic filariasis in west African urban areas: is implementation of mass drug administration necessary?
Koudou BG, de Souza DK, Biritwum N-K, et al. Lancet Infect Dis. 2018.
Abstract Lymphatic filariasis in Africa is caused by the parasite Wuchereria bancrofti and remains a major cause of morbidity and disability in 74 countries globally. A key strategy of the Global Programme for the Elimination of Lymphatic Filariasis, which has a target elimination date of 2020, is the treatment of entire endemic communities through mass drug administration of albendazole in combination with either ivermectin or diethylcarbamazine.
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Leishmaniasis in Sri Lanka: spatial distribution and seasonal variations from 2009 to 2016.
Galgamuwa LS, Dharmaratne SD, Iddawela D. Parasit Vectors. 2018; 11(1):60.
Abstract Leishmaniasis is listed as one of the eight neglected tropical diseases by the World Health Organization and the number of cases in endemic areas has seen a sharp rise in the past decade. In Sri Lanka, leishmaniasis is considered as a notifiable disease from 2008 and has seen a rising trend of incidence since then. This is the first study describing the burden, seasonal variation and spatial distribution of leishmaniasis in Sri Lanka since the disease has been included as a notifiable disease.
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PLOS NTDs celebrates our 10th anniversary: Looking forward to the next decade.
Aksoy S, Walson JL. PLoS Negl Trop Dis. 2018; 12(1):e0006176.
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Assessment of WASH scenarios in urban and rural schools of a small city in the Brazilian Amazon.
Borges-Pedro JP, Müller P, Nunes AP, et al. Acta Amazon. 2018; 48(1):75-82.
Abstract This study analyzed environmental aspects of county and state managed public schools within Tefé county in the Brazilian Amazon, using the WASH concept (Water, Sanitation and Hygiene) developed by UNICEF and OMS. WASH is a strategy used since 1995, when child mortality rates were on the rise. Research was conducted using a questionnaire applied to employees of 19 primary and secondary schools, and based on WASH principles.
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Inferring the risk factors behind the geographical spread and transmission of Zika in the Americas.
Gardner LM, Bóta A, Gangavarapu K, et al. PLoS Negl Trop Dis. 2018; 12(1):e0006194.
Abstract An unprecedented Zika virus epidemic occurred in the Americas during 2015-2016. Our study complements several recent studies which have mapped epidemiological elements of Zika, by introducing a newly proposed methodology to simultaneously estimate the contribution of various risk factors for geographic spread resulting in local transmission and to compute the risk of spread (or re-introductions) between each pair of regions.
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Geographical distribution of soil transmitted helminths and the effects of community type in South Asia and South East Asia - A systematic review.
Silver ZA, Kaliappan SP, Samuel P, et al. PLoS Negl Trop Dis. 2018; 12(1):e0006153.
Abstract Soil-transmitted helminth (STH) infections are among the most prevalent neglected tropical diseases (NTD) worldwide. Since the publication of the WHO road map to combat NTD in 2012, there has been a renewed commitment to control STH. In this study, we analysed the geographical distribution and effect of community type on prevalence of hookworm, Trichuris and Ascaris in south Asia and south east Asia.
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Risk factors for Mycobacterium ulcerans infection (Buruli Ulcer) in Togo ─ a case-control study in Zio and Yoto districts of the maritime region.
Maman I, Tchacondo T, Kere AB, et al. BMC Infect. Dis. 2018; 18(1):48.
Abstract Buruli ulcer (BU) is a neglected mycobacterial skin infection caused by Mycobacterium ulcerans. This disease mostly affects poor rural populations, especially in areas with low hygiene standards and sanitation coverage. The objective of this study was to identify these risk factors in the districts of Zio and Yoto of the Maritime Region in Togo.
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Interventions to maximize facial cleanliness and achieve environmental improvement for trachoma elimination: A review of the grey literature.
Delea MG, Solomon H, Solomon AW, et al. PLoS Negl Trop Dis. 2018; 12(1):e0006178.
Abstract Efforts are underway to scale-up the facial cleanliness and environmental improvement (F&E) components of the World Health Organization's SAFE strategy for elimination of trachoma as a public health problem. Improving understanding of the F&E intervention landscape could inform advancements prior to scale-up, and lead to more effective and sustained behavior change.
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Podoconiosis: Nonfilarial endemic elephantiasis.
Olanipekun T, Qin H, Fransua M. Eur J Intern Med. 2018.
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Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015.
Montresor A, Trouleau W, Mupfasoni D, et al. Trans. R. Soc. Trop. Med. Hyg. 2018.
Abstract Preventive chemotherapy (PC), the large-scale administration of anthelminthics, is recommended by the World Health Organization (WHO) for the control of soil-transmitted helminthiasis (STH). Since 2010, donated anthelminthics for STH have boosted the implementation of PC programmes in children, achieving global coverage of more than 60% in 2015. The WHO Global Health Estimates attribute an annual loss of over 3.3 million disability-adjusted life-years (DALYs) to STH. The aim of this study is to estimate the impact of PC programmes on child morbidity.
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