Tuesday, May 5, 2015

(LML) Parenteral treatment of leprosy reactions

 

Leprosy Mailing List – May 5,  2015

Ref.: (LML) Parenteral treatment of leprosy reactions    

From:  Jingquan Wang, Zhejiang, PR China


 

Dear Pieter,


Greetings from a leprosy colony in Zhejiang Province, China. I write this letter in response to the request from Herman Harun, LML April 28, 2015.


I have seen a leprosy reaction case treated with a bolus of 150mg Dexamethasone for 3 days and continued orally prednisone prescribed by a village doctor in Jiangsu, China.

 

Fifteen years ago, I worked as a leprosy control doctor in a small county in Jiangsu, China. One day, the patient aged 60 years old, BL classification, came to our leprosy control section for regular treatment. He had been treated with MDT for over 3 years. The patient presented with oedematous skin lesions and swollen nerve trunks with nerve pains. So we diagnosed him type 1 reaction and asked him to go to the village medical station for further treatment. We give him a prescription of hydrocortisone 150 mg infusion with glucose 250 ml. Unfortunately, the village doctor had no hydrocortisone injection, so he replaced it with dexamethasone of same dosage (of 150 mg dexamethasone). After three days infusion, the patient came to our hospital and told me the village doctor treated him with dexamethasone of same dosage. We immediately asked the village doctor stop the treatment and give the patient prednisone 80 mg /day for several weeks. However, the leprosy reaction soon relapsed. It turned out that the patient had developed adrenal insufficiency and needed oral prednisone replacement of adrenal function for life. So I do not think severe leprosy reaction should be treated with methylprednisolone pulse therapy. Such bolus therapy could do more harm than good in treating leprosy reaction. I strongly suggest not to use this technique to treat leprosy reactions.

 

I am still very sorry for the patient. I have heard he had passed ten years ago. I scolded the village doctor. The patient forgave him.

 

Best wishes,

 

Jingquan Wang

 

Chief Physician,

Department of leprosy treatment

Institute of Dermatology of Zhejiang Province,China

E-mail:767790635@qq.com

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com




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FW: (3) (LML) Infoleps Choice of new (e) publications on leprosy - 20150501




From: editorlml@gmail.com
To: editorlml@gmail.com
Subject: (3) (LML) Infoleps Choice of new (e) publications on leprosy - 20150501
Date: Mon, 4 May 2015 09:53:46 +0200

Leprosy Mailing List – May 4,  2015

Ref.:    (LML) Infoleps Choice of new (e) publications on leprosy - 20150501

From:  Jiske Erlings, Amsterdam, the Netherlands


Dear Pieter,

Greetings from Infolep!

Below you will find a selection of recent publications on leprosy. Feel free to contact me to receive the full text versions if a link to the full text is not included.
You might also be interested in our collection of publications on cross-cutting issues in Neglected Tropical Diseases. An overview of this rapidly growing collection can be found here:
http://www.leprosy-information.org/category/collection/infontds-cross-cutting-issues

Our WASH collection can be found here: http://www.leprosy-information.org/category/subject/wash

The issues with Google Chrome have been solved. If you still have trouble accessing the portal please let us know. 


With kind regards,

Jiske Erlings

INFOLEP Information specialist

Follow Infolep on Facebook or Twitter

To subscribe/unsubscribe to this service, please send an email to: infolep@leprastichting.nl

 


Publications


Eliminating Discrimination Against Persons Affected By Leprosy. Government of India, Law Commission of India. Report No 256. 2015. Full text online:
http://www.leprosy-information.org/resource/eliminating-discrimination-against-persons-affected-leprosy

 


New Journal Articles

Brandmeir NJ, Sather MD. Spinal Cord Stimulation for the Treatment of Neuropathic Pain Associated With Leprosy: A Case Report. Neuromodulation. 2015 Apr 10. Abstract: http://www.leprosy-information.org/resource/spinal-cord-stimulation-treatment-neuropathic-pain-associated-leprosy-case-report


Breen DP, Deeb J, Vaidya S, Lockwood DN, Radunovic A. Leprosy: a 'common' and curable cause of peripheral neuropathy with skin lesions. J R Coll Physicians Edinb. 2015 Mar;45(1):38-42. Full text:
http://www.leprosy-information.org/resource/leprosy-common-and-curable-cause-peripheral-neuropathy-skin-lesions

Chaitanya VS, Das M, Bhat P, Ebenezer M. Computational Modelling of Dapsone Interaction with Dihydropteroate Synthase in Mycobacterium leprae; Insights into Molecular Basis of Dapsone Resistance in Leprosy. J Cell Biochem. 2015 Apr 2. Abstract: http://www.leprosy-information.org/resource/computational-modelling-dapsone-interaction-dihydropteroate-synthase-mycobacterium-leprae

Ciampi de Andrade D. Pain in leprosy: general challenges of a singular disease. Pain. 2015 Mar 24. Abstract: http://www.leprosy-information.org/resource/pain-leprosy-general-challenges-singular-disease

De A, Surana TV, Biswas S, Reja AH, Chatterjee G. Isolated tenosynovitis as a sole manifestation: the great mimicker still continues to surprise us. Indian J Dermatol. 2015 Mar-Apr;60(2):213. Full text: http://www.leprosy-information.org/resource/isolated-tenosynovitis-sole-manifestation-great-mimicker-still-continues-surprise-us

Duarte-Cunha M, Marcelo da Cunha G, Souza-Santos R. Geographical heterogeneity in the analysis of factors associated with leprosy in an endemic area of Brazil: are we eliminating the disease? BMC Infect Dis. 2015 Apr 25;15(1):196. Full text: http://www.leprosy-information.org/resource/geographical-heterogeneity-analysis-factors-associated-leprosy-endemic-area-brazil-are-we

Dutra FA, Araújo MG, Farah KP, Maciel MM, Lucas Junior FD, Araújo SA, Guedes AC. [Multibacillary leprosy in a renal recipient patient: a case report]. J Bras Nefrol. 2015 Jan-Mar;37(1):131-134. Portuguese. Full text: http://www.leprosy-information.org/resource/multibacillary-leprosy-renal-recipient-patient-case-report

Ferreira CP, Medeiros V, Maia RC, Sales AM, da Nery JAC. Secondary Syphilis Mimicking Leprosy Type1 Reaction. Journal Of Immunological Techniques In Infectious Diseases. 2015;4(1). Full text: http://www.leprosy-information.org/resource/secondary-syphilis-mimicking-leprosy-type1-reaction

Gupta V, Consul A, Swamy MK. Zancolli lasso procedure for correction of paralytic claw hands. J Orthop Surg (Hong Kong). 2015 Apr;23(1):15-8. Full text: http://www.leprosy-information.org/resource/zancolli-lasso-procedure-correction-paralytic-claw-hands

Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected Tropical Diseases among the Association of Southeast Asian Nations (ASEAN): Overview and Update. PLoS Negl Trop Dis. 2015 Apr 16;9(4):e0003575. Full text: http://www.leprosy-information.org/resource/neglected-tropical-diseases-among-association-southeast-asian-nations-asean-overview-and

Kumar B. World Leprosy Day 2015: Renewing commitment for a leprosy free world! Indian J Med Res. 2015 Jan;141(1):1-4. Full text: http://www.leprosy-information.org/resource/world-leprosy-day-2015-renewing-commitment-leprosy-free-world

Lusli M, Zweekhorst MBM, Miranda-Galarza B, Peters RMH, Cummings S, Seda FSSE, Bunders, JFG, Irwanto. Dealing with Stigma: Experiences of Persons Affected by Disabilities and Leprosy. BioMed Research International. 2015, 9 p.
Full text:
http://www.leprosy-information.org/resource/dealing-stigma-experiences-persons-affected-disabilities-and-leprosy

Lyrio EC, Campos-Souza IC, Corrêa C, Lechuga G, Verícimo M, Castro HC, Bourguignon SC, Faria SC, Ratcliffe N, Declercq W, Santos DO. Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: New frontiers in the cellular immunology of leprosy. Exp Dermatol. 2015 Apr 1. Abstract: http://www.leprosy-information.org/resource/interaction-mycobacterium-leprae-hacat-human-keratinocyte-cell-line-new-frontiers-cellular

Matsuki T, Okano Y, Aoki Y, Ishida Y, Hatano K, Kumano K. [Effectiveness of thalidomide for erythema nodosum leprosum (ENL): retrospective study of 20 Japanese cases in National Sanatrium Oku-Komyoen]. Nihon Hansenbyo Gakkai Zasshi. 2014 Dec;83(3):1-6. Japanese. Abstract: http://www.leprosy-information.org/resource/effectiveness-thalidomide-erythema-nodosum-leprosum-enl-retrospective-study-20-japanese

 

Nandwani R, Totade S, Gupta U, Jain M. Role of fine needle aspiration cytology in diagnosing leprosy: in a tertiary care hospital. International Journal Of Research In Medical Sciences. 2015;3(3):749-756. Full text: http://www.leprosy-information.org/resource/role-fine-needle-aspiration-cytology-diagnosing-leprosy-tertiary-care-hospital

Nogueira PS, Moura ER, Dias AA, Américo CF, Aguiar LR, Valente MM. Characteristics of pregnant and lactating women with leprosy. Rev Soc Bras Med Trop. 2015 Jan-Feb;48(1):96-8. Full text: http://www.leprosy-information.org/resource/characteristics-pregnant-and-lactating-women-leprosy

Pattanaprichakul P, Chayangsu O, Lertrujiwanit K, Chairatchaneeboon M.
Assessment of Non-Dermatologists? Knowledge Regarding Clinical Diagnosis of Leprosy and Practice in Slit-Skin Smear as a Basic Investigation. Siriraj Med J. 2015;67(2):66-71.
Full text: http://www.leprosy-information.org/resource/assessment-non-dermatologists-knowledge-regarding-clinical-diagnosis-leprosy-and-practice

Rao RG. Prof. Dr. B. Narasimha Rao. Indian J Dermatol Venereol Leprol. 2015 Mar-Apr;81(2):231. Full text: http://www.leprosy-information.org/resource/prof-dr-b-narasimha-rao

Porto AC, Figueira RB, Barreto JA, Lauris JR. Evaluation of the social, clinical and laboratorial profile of patients diagnosed with leprosy in a reference center in São Paulo. An Bras Dermatol. 2015 Mar-Apr;90(2):169-177. Full text: http://www.leprosy-information.org/resource/evaluation-social-clinical-and-laboratorial-profile-patients-diagnosed-leprosy-reference

Rocha MC, Lima RB, Stevens A, Gutierrez MM, Garcia LP. [Deaths with leprosy as the underlying cause recorded in Brazil: use of data base linkage to enhance information]. Cien Saude Colet. 2015 Apr;20(4):1017-1026. Portuguese.Full text: http://www.leprosy-information.org/resource/deaths-leprosy-underlying-cause-recorded-brazil-use-data-base-linkage-enhance-information

Sahu S, Goyal V, Dhiraaj S, Kishore K, Singh PK. A very common case become rare: Anesthetic considerations of lepromatous leprosy. Anesth Essays Res. 2011 Jul-Dec;5(2):207-10. Full text: http://www.leprosy-information.org/resource/very-common-case-become-rare-anesthetic-considerations-lepromatous-leprosy

Sardesai VR. Leprosy elimination: A myth or reality. J Neurosci Rural Pract. 2015 Apr-Jun;6(2):137-8. Full text: http://www.leprosy-information.org/resource/leprosy-elimination-myth-or-reality

Shukla LK, Patel RN, Patel SV, Baxi RK. Evaluation of the effect of Block Level Awareness Campaign on performance indicators of National Leprosy Elimination Program in Vadodara district, Gujarat, India. Indian J Dermatol Venereol Leprol. 2015 Apr 8. Full text: http://www.leprosy-information.org/resource/evaluation-effect-block-level-awareness-campaign-performance-indicators-national-leprosy

Silva PE, Costa PS, Ávila MP, Suhadolnik ML, Reis MP, Salgado AP, Lima MF, Chartone-Souza E, Nascimento AM. Leprous lesion presents enrichment of opportunistic pathogenic bacteria. Springerplus. 2015 Apr 18;4:187. Full text: http://www.leprosy-information.org/resource/leprous-lesion-presents-enrichment-opportunistic-pathogenic-bacteria

Smith WC, van Brakel W, Gillis T, Saunderson P, Richardus JH.
The missing millions: a threat to the elimination of leprosy. PLoS Negl Trop Dis. 2015 Apr 23;9(4):e0003658. Full text:
http://www.leprosy-information.org/resource/missing-millions-threat-elimination-leprosy

Thakur S, Dworkin RH, Haroun OM, Lockwood DN, Rice AS. Acute and chronic pain associated with leprosy. Pain. 2015 Mar 31. Abstract: http://www.leprosy-information.org/resource/acute-and-chronic-pain-associated-leprosy

Tiwari Mamata, Sabin Ranabhat, and Sushna Maharjan. Clinico-Histopathological Correlation Of Leprosy: A Retrospective Study Of Skin Biopsy Specimens In Chitwan Medical College. International Journal of Medical Science Research and Practice. 1 (2015): 8-11. Full text: http://www.leprosy-information.org/resource/clinico-histopathological-correlation-leprosy-retrospective-study-skin-biopsy-specimens

Tricco AC, Cogo E, Isaranuwatchai W, Khan PA, Sanmugalingham G, Antony J, Hoch JS, Straus SE. A systematic review of cost-effectiveness analyses of complex wound interventions reveals optimal treatments for specific wound types. BMC Med. 2015 Apr 22;13:90. Full text: http://www.leprosy-information.org/resource/systematic-review-cost-effectiveness-analyses-complex-wound-interventions-reveals-optimal

Ukwaja KN. Interactions between leprosy and human immunodeficiency virus: More questions than answers. J Neurosci Rural Pract. 2015 Apr-Jun;6(2):135-6. Full text: http://www.leprosy-information.org/resource/interactions-between-leprosy-and-human-immunodeficiency-virus-more-questions-answers

Vick GL, Tillman EA, Fiala KH. Leprosy in a texan. Proc (Bayl Univ Med Cent). 2015 Apr;28(2):231-2. Full text: http://www.leprosy-information.org/resource/leprosy-texan

Wassie L, Woldeamanuel Y, Gebre-Mariam S, Feleke Y, Temam F, Hailu A, Abay H, Zerihun Z, Bussa S, Aberra L, Tarekegne G, Gebre-Yohannes A, Aseffa A. Research ethics review practices: experiences of the Armauer Hansen Research Institute/All Africa Leprosy and Tuberculosis Rehabilitation and Training Center Ethics Review Committee, Ethiopia. Ethiop Med J. 2015 Jan;53 Suppl 1:15-24. Full text: http://www.leprosy-information.org/resource/research-ethics-review-practices-experiences-armauer-hansen-research-instituteall-africa

Yokota Y. [Leprosy and human rights: trends in Japan and in the world]. Nihon Hansenbyo Gakkai Zasshi. 2014 Dec;83(3):15-9. Japanese. Abstract: http://www.leprosy-information.org/resource/leprosy-and-human-rights-trends-japan-and-world


Journals  & Newsletters

 

Community Eye Health: http://www.cehjournal.org/wp-content/uploads/Working-with-communities-to-improve-their-eye-health.pdf

Disability, CBR & Inclusive Development: http://dcidj.org/

Leprosy Review: 2015-1 http://www.lepra.org.uk/Pages/FAQs/Category/volume-85

Revista de Leprología: http://www.leprosy-information.org/resource/revista-de-leprologia

WHO Goodwill Ambassador's Newsletter for the elimination of leprosy: http://www.leprosy-information.org/resource/who-goodwill-ambassador-s-newsletter-elimination-leprosy


Training Videos


LepClips, short films for training in Leprosy by NLR Foundation  English: https://www.youtube.com/playlist?list=PL3RVWXokkaVoCfrGTD47BelP2cZy_M_IN

Hindi: https://www.youtube.com/playlist?list=PL3RVWXokkaVrKjqFN0l3arwKWLGTJUDFR


Leprosy Self Care Group in Indonesia video https://www.youtube.com/watch?v=E_WvtTXdUVg&feature=youtu.be


Other Information Sources

You might also be interested in The Leprosy Mailing List (LML), a free moderated email list that allows all persons interested in this theme to share ideas, information, experiences, questions. http://leprosymailinglist.blogspot.nl/

 

Jiske Erlings

Medewerker InfoLep / Information Officer

Infolep Leprosy Information Services

 

Postbus / P.O. Box 95005

1090 HA Amsterdam

The Netherlands

Tel:

+31 20 5950530

Mob:

-

Email:

J.Erlings@Leprastichting.NL

Web:

www.leprosy-information.org


P Please consider the environment - do you really need to print this e-mail?


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com




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Monday, May 4, 2015

(LML) Infoleps Choice of new (e) publications on leprosy - 20150501

Leprosy Mailing List – May 4,  2015

Ref.:    (LML) Infoleps Choice of new (e) publications on leprosy - 20150501

From:  Jiske Erlings, Amsterdam, the Netherlands


Dear Pieter,

Greetings from Infolep!

Below you will find a selection of recent publications on leprosy. Feel free to contact me to receive the full text versions if a link to the full text is not included.
You might also be interested in our collection of publications on cross-cutting issues in Neglected Tropical Diseases. An overview of this rapidly growing collection can be found here:
http://www.leprosy-information.org/category/collection/infontds-cross-cutting-issues

Our WASH collection can be found here: http://www.leprosy-information.org/category/subject/wash

The issues with Google Chrome have been solved. If you still have trouble accessing the portal please let us know. 


With kind regards,

Jiske Erlings

INFOLEP Information specialist

Follow Infolep on Facebook or Twitter

To subscribe/unsubscribe to this service, please send an email to: infolep@leprastichting.nl

 


Publications


Eliminating Discrimination Against Persons Affected By Leprosy. Government of India, Law Commission of India. Report No 256. 2015. Full text online:
http://www.leprosy-information.org/resource/eliminating-discrimination-against-persons-affected-leprosy

 


New Journal Articles

Brandmeir NJ, Sather MD. Spinal Cord Stimulation for the Treatment of Neuropathic Pain Associated With Leprosy: A Case Report. Neuromodulation. 2015 Apr 10. Abstract: http://www.leprosy-information.org/resource/spinal-cord-stimulation-treatment-neuropathic-pain-associated-leprosy-case-report


Breen DP, Deeb J, Vaidya S, Lockwood DN, Radunovic A. Leprosy: a 'common' and curable cause of peripheral neuropathy with skin lesions. J R Coll Physicians Edinb. 2015 Mar;45(1):38-42. Full text:
http://www.leprosy-information.org/resource/leprosy-common-and-curable-cause-peripheral-neuropathy-skin-lesions

Chaitanya VS, Das M, Bhat P, Ebenezer M. Computational Modelling of Dapsone Interaction with Dihydropteroate Synthase in Mycobacterium leprae; Insights into Molecular Basis of Dapsone Resistance in Leprosy. J Cell Biochem. 2015 Apr 2. Abstract: http://www.leprosy-information.org/resource/computational-modelling-dapsone-interaction-dihydropteroate-synthase-mycobacterium-leprae

Ciampi de Andrade D. Pain in leprosy: general challenges of a singular disease. Pain. 2015 Mar 24. Abstract: http://www.leprosy-information.org/resource/pain-leprosy-general-challenges-singular-disease

De A, Surana TV, Biswas S, Reja AH, Chatterjee G. Isolated tenosynovitis as a sole manifestation: the great mimicker still continues to surprise us. Indian J Dermatol. 2015 Mar-Apr;60(2):213. Full text: http://www.leprosy-information.org/resource/isolated-tenosynovitis-sole-manifestation-great-mimicker-still-continues-surprise-us

Duarte-Cunha M, Marcelo da Cunha G, Souza-Santos R. Geographical heterogeneity in the analysis of factors associated with leprosy in an endemic area of Brazil: are we eliminating the disease? BMC Infect Dis. 2015 Apr 25;15(1):196. Full text: http://www.leprosy-information.org/resource/geographical-heterogeneity-analysis-factors-associated-leprosy-endemic-area-brazil-are-we

Dutra FA, Araújo MG, Farah KP, Maciel MM, Lucas Junior FD, Araújo SA, Guedes AC. [Multibacillary leprosy in a renal recipient patient: a case report]. J Bras Nefrol. 2015 Jan-Mar;37(1):131-134. Portuguese. Full text: http://www.leprosy-information.org/resource/multibacillary-leprosy-renal-recipient-patient-case-report

Ferreira CP, Medeiros V, Maia RC, Sales AM, da Nery JAC. Secondary Syphilis Mimicking Leprosy Type1 Reaction. Journal Of Immunological Techniques In Infectious Diseases. 2015;4(1). Full text: http://www.leprosy-information.org/resource/secondary-syphilis-mimicking-leprosy-type1-reaction

Gupta V, Consul A, Swamy MK. Zancolli lasso procedure for correction of paralytic claw hands. J Orthop Surg (Hong Kong). 2015 Apr;23(1):15-8. Full text: http://www.leprosy-information.org/resource/zancolli-lasso-procedure-correction-paralytic-claw-hands

Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected Tropical Diseases among the Association of Southeast Asian Nations (ASEAN): Overview and Update. PLoS Negl Trop Dis. 2015 Apr 16;9(4):e0003575. Full text: http://www.leprosy-information.org/resource/neglected-tropical-diseases-among-association-southeast-asian-nations-asean-overview-and

Kumar B. World Leprosy Day 2015: Renewing commitment for a leprosy free world! Indian J Med Res. 2015 Jan;141(1):1-4. Full text: http://www.leprosy-information.org/resource/world-leprosy-day-2015-renewing-commitment-leprosy-free-world

Lusli M, Zweekhorst MBM, Miranda-Galarza B, Peters RMH, Cummings S, Seda FSSE, Bunders, JFG, Irwanto. Dealing with Stigma: Experiences of Persons Affected by Disabilities and Leprosy. BioMed Research International. 2015, 9 p.
Full text:
http://www.leprosy-information.org/resource/dealing-stigma-experiences-persons-affected-disabilities-and-leprosy

Lyrio EC, Campos-Souza IC, Corrêa C, Lechuga G, Verícimo M, Castro HC, Bourguignon SC, Faria SC, Ratcliffe N, Declercq W, Santos DO. Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: New frontiers in the cellular immunology of leprosy. Exp Dermatol. 2015 Apr 1. Abstract: http://www.leprosy-information.org/resource/interaction-mycobacterium-leprae-hacat-human-keratinocyte-cell-line-new-frontiers-cellular

Matsuki T, Okano Y, Aoki Y, Ishida Y, Hatano K, Kumano K. [Effectiveness of thalidomide for erythema nodosum leprosum (ENL): retrospective study of 20 Japanese cases in National Sanatrium Oku-Komyoen]. Nihon Hansenbyo Gakkai Zasshi. 2014 Dec;83(3):1-6. Japanese. Abstract: http://www.leprosy-information.org/resource/effectiveness-thalidomide-erythema-nodosum-leprosum-enl-retrospective-study-20-japanese

 

Nandwani R, Totade S, Gupta U, Jain M. Role of fine needle aspiration cytology in diagnosing leprosy: in a tertiary care hospital. International Journal Of Research In Medical Sciences. 2015;3(3):749-756. Full text: http://www.leprosy-information.org/resource/role-fine-needle-aspiration-cytology-diagnosing-leprosy-tertiary-care-hospital

Nogueira PS, Moura ER, Dias AA, Américo CF, Aguiar LR, Valente MM. Characteristics of pregnant and lactating women with leprosy. Rev Soc Bras Med Trop. 2015 Jan-Feb;48(1):96-8. Full text: http://www.leprosy-information.org/resource/characteristics-pregnant-and-lactating-women-leprosy

Pattanaprichakul P, Chayangsu O, Lertrujiwanit K, Chairatchaneeboon M.
Assessment of Non-Dermatologists? Knowledge Regarding Clinical Diagnosis of Leprosy and Practice in Slit-Skin Smear as a Basic Investigation. Siriraj Med J. 2015;67(2):66-71.
Full text: http://www.leprosy-information.org/resource/assessment-non-dermatologists-knowledge-regarding-clinical-diagnosis-leprosy-and-practice

Rao RG. Prof. Dr. B. Narasimha Rao. Indian J Dermatol Venereol Leprol. 2015 Mar-Apr;81(2):231. Full text: http://www.leprosy-information.org/resource/prof-dr-b-narasimha-rao

Porto AC, Figueira RB, Barreto JA, Lauris JR. Evaluation of the social, clinical and laboratorial profile of patients diagnosed with leprosy in a reference center in São Paulo. An Bras Dermatol. 2015 Mar-Apr;90(2):169-177. Full text: http://www.leprosy-information.org/resource/evaluation-social-clinical-and-laboratorial-profile-patients-diagnosed-leprosy-reference

Rocha MC, Lima RB, Stevens A, Gutierrez MM, Garcia LP. [Deaths with leprosy as the underlying cause recorded in Brazil: use of data base linkage to enhance information]. Cien Saude Colet. 2015 Apr;20(4):1017-1026. Portuguese.Full text: http://www.leprosy-information.org/resource/deaths-leprosy-underlying-cause-recorded-brazil-use-data-base-linkage-enhance-information

Sahu S, Goyal V, Dhiraaj S, Kishore K, Singh PK. A very common case become rare: Anesthetic considerations of lepromatous leprosy. Anesth Essays Res. 2011 Jul-Dec;5(2):207-10. Full text: http://www.leprosy-information.org/resource/very-common-case-become-rare-anesthetic-considerations-lepromatous-leprosy

Sardesai VR. Leprosy elimination: A myth or reality. J Neurosci Rural Pract. 2015 Apr-Jun;6(2):137-8. Full text: http://www.leprosy-information.org/resource/leprosy-elimination-myth-or-reality

Shukla LK, Patel RN, Patel SV, Baxi RK. Evaluation of the effect of Block Level Awareness Campaign on performance indicators of National Leprosy Elimination Program in Vadodara district, Gujarat, India. Indian J Dermatol Venereol Leprol. 2015 Apr 8. Full text: http://www.leprosy-information.org/resource/evaluation-effect-block-level-awareness-campaign-performance-indicators-national-leprosy

Silva PE, Costa PS, Ávila MP, Suhadolnik ML, Reis MP, Salgado AP, Lima MF, Chartone-Souza E, Nascimento AM. Leprous lesion presents enrichment of opportunistic pathogenic bacteria. Springerplus. 2015 Apr 18;4:187. Full text: http://www.leprosy-information.org/resource/leprous-lesion-presents-enrichment-opportunistic-pathogenic-bacteria

Smith WC, van Brakel W, Gillis T, Saunderson P, Richardus JH.
The missing millions: a threat to the elimination of leprosy. PLoS Negl Trop Dis. 2015 Apr 23;9(4):e0003658. Full text:
http://www.leprosy-information.org/resource/missing-millions-threat-elimination-leprosy

Thakur S, Dworkin RH, Haroun OM, Lockwood DN, Rice AS. Acute and chronic pain associated with leprosy. Pain. 2015 Mar 31. Abstract: http://www.leprosy-information.org/resource/acute-and-chronic-pain-associated-leprosy

Tiwari Mamata, Sabin Ranabhat, and Sushna Maharjan. Clinico-Histopathological Correlation Of Leprosy: A Retrospective Study Of Skin Biopsy Specimens In Chitwan Medical College. International Journal of Medical Science Research and Practice. 1 (2015): 8-11. Full text: http://www.leprosy-information.org/resource/clinico-histopathological-correlation-leprosy-retrospective-study-skin-biopsy-specimens

Tricco AC, Cogo E, Isaranuwatchai W, Khan PA, Sanmugalingham G, Antony J, Hoch JS, Straus SE. A systematic review of cost-effectiveness analyses of complex wound interventions reveals optimal treatments for specific wound types. BMC Med. 2015 Apr 22;13:90. Full text: http://www.leprosy-information.org/resource/systematic-review-cost-effectiveness-analyses-complex-wound-interventions-reveals-optimal

Ukwaja KN. Interactions between leprosy and human immunodeficiency virus: More questions than answers. J Neurosci Rural Pract. 2015 Apr-Jun;6(2):135-6. Full text: http://www.leprosy-information.org/resource/interactions-between-leprosy-and-human-immunodeficiency-virus-more-questions-answers

Vick GL, Tillman EA, Fiala KH. Leprosy in a texan. Proc (Bayl Univ Med Cent). 2015 Apr;28(2):231-2. Full text: http://www.leprosy-information.org/resource/leprosy-texan

Wassie L, Woldeamanuel Y, Gebre-Mariam S, Feleke Y, Temam F, Hailu A, Abay H, Zerihun Z, Bussa S, Aberra L, Tarekegne G, Gebre-Yohannes A, Aseffa A. Research ethics review practices: experiences of the Armauer Hansen Research Institute/All Africa Leprosy and Tuberculosis Rehabilitation and Training Center Ethics Review Committee, Ethiopia. Ethiop Med J. 2015 Jan;53 Suppl 1:15-24. Full text: http://www.leprosy-information.org/resource/research-ethics-review-practices-experiences-armauer-hansen-research-instituteall-africa

Yokota Y. [Leprosy and human rights: trends in Japan and in the world]. Nihon Hansenbyo Gakkai Zasshi. 2014 Dec;83(3):15-9. Japanese. Abstract: http://www.leprosy-information.org/resource/leprosy-and-human-rights-trends-japan-and-world


Journals  & Newsletters

 

Community Eye Health: http://www.cehjournal.org/wp-content/uploads/Working-with-communities-to-improve-their-eye-health.pdf

Disability, CBR & Inclusive Development: http://dcidj.org/

Leprosy Review: 2015-1 http://www.lepra.org.uk/Pages/FAQs/Category/volume-85

Revista de Leprología: http://www.leprosy-information.org/resource/revista-de-leprologia

WHO Goodwill Ambassador’s Newsletter for the elimination of leprosy: http://www.leprosy-information.org/resource/who-goodwill-ambassador-s-newsletter-elimination-leprosy


Training Videos


LepClips, short films for training in Leprosy by NLR Foundation  English: https://www.youtube.com/playlist?list=PL3RVWXokkaVoCfrGTD47BelP2cZy_M_IN

Hindi: https://www.youtube.com/playlist?list=PL3RVWXokkaVrKjqFN0l3arwKWLGTJUDFR


Leprosy Self Care Group in Indonesia video https://www.youtube.com/watch?v=E_WvtTXdUVg&feature=youtu.be


Other Information Sources

You might also be interested in The Leprosy Mailing List (LML), a free moderated email list that allows all persons interested in this theme to share ideas, information, experiences, questions. http://leprosymailinglist.blogspot.nl/

 

Jiske Erlings

Medewerker InfoLep / Information Officer

Infolep Leprosy Information Services

 

Postbus / P.O. Box 95005

1090 HA Amsterdam

The Netherlands

Tel:

+31 20 5950530

Mob:

-

Email:

J.Erlings@Leprastichting.NL

Web:

www.leprosy-information.org


P Please consider the environment - do you really need to print this e-mail?


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com




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Friday, May 1, 2015

(LML) Parenteral treatment of leprosy reactions

Leprosy Mailing List – May 1, 2015

Ref.: (LML) Parenteral treatment of leprosy reactions  

From:  Herman Harun, Jakarta, Indonesia


Dear Pieter,

Our colleague Dr. Indropo Agnusi from Surabaya asked me for which (leprosy) reaction a high dose of prednisolone should be given.

First of all, I must say that I am a chest physician and specialist in TB control. A ‘large’ majority of my Asthma and COPD patients are prescribed corticosteroids. If symptoms are moderately severe, or deemed annoying, I would give 125 mg prednisolone intravenously. Shortness of breath, cough and sputum production would decrease dramatically. As for TB in pleurisy, I would prescribe 16 mg prednisolone daily for at least 2 months, when the pleural fluid will be absorbed (almost) completely.

In my experience as lung specialist (36 years including 3 years in the Netherlands),  I have, fortunately enough,  not met steroid dependency or cases of adrenal suppression.

I am not a leprosy doctor. But I became interested in the dramatic and tragic leprosy reactions, because my daughter’s involvement with leprosy work. So I wonder if larger doses of prednisolone (given parenteral 125 mg) would be helpful to - in some way - relieve the pain and suffering from leprosy reactions. The official regimen for leprosy reactions obviously, should be applied as usual.

Answering Dr Agnusi question, I can only offer the advice of the well-known specialist in the management of leprosy reactions, Dr Ben Naafs.

Dr Naafs gives for severe cases of ENL  high doses of 100 – 180 mg prednisone (for the initial treatment of such cases methylprednisolone  i.v. for 3 days would be a good alternative) and then reduced the dose until 0 mg within a month. In case when the ENL relapses, he would double the dose of prednisone (the dose at the moment of relapse) and reduce to zero in one month. He does not believe that a small maintenance dose prednisone would be helpful to prevent a relapse of the ENL

 

Best regards,

 

Muherman Harun

The Bellezza Permata Hijau

Albergo Tower

31st floor. Apt. 09-10

Jl. Letjen Soepeno

South Jakarta 12210

Tel: (021) 30485500

Mobile: 08990635289 / 0818153808

email: muhermanharun@gmail.com

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 




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