Leprosy Mailing List – June 19, 2026
Ref.: (LML) Discussion Paper: Revisiting Bacillary Persistence, Viability, and Transmission in Leprosy
From: Isabela Goulart, Uberländia, Brazil
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Dear Editor,
Please find attached a discussion paper entitled:
"Revisiting Bacillary Persistence, Viability, and Transmission: Reflections on the Study by Neumann et al. (2022)."
This discussion paper was prepared in response to the findings reported by Neumann et al. regarding the heterogeneous persistence of molecular markers of Mycobacterium leprae viability during multidrug therapy in multibacillary patients.
The discussion explores some conceptual and biological implications of these findings and raises questions regarding the relationships among bacillary viability, infectivity, and epidemiologically relevant transmission in leprosy.
We hope it may stimulate discussion among members of the Leprosy Mailing List and would greatly appreciate comments and perspectives from colleagues.
Kind regards,
Dr. Isabela Maria Bernardes Goulart
on behalf of the authors
Dr Isabela Maria Bernardes Goulart, MD, PhD
Full Professor – School of Medicine - Universidade Federal de Uberlândia (UFU)
Coordinator and Head of the National Reference Center for Sanitary Dermatology and Hansenology
Clinical Hospital - EBSERH - UFU, Uberlândia/MG, Brasil
credesh.hc-ufu@ebserh.gov.br; isabela.goulart@ebserh.gov.br; imbgoulart@ufu.br; imbgoulart@gmail.com
Phone: +55 (34) 3218-2828 ramal 5569
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LML - S Deepak, B Naafs, S Noto and P Schreuder
LML blog link: http://leprosymailinglist.blogspot.it/
Contact: Dr Pieter Schreuder << edit...@gmail.com
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