Monday, May 21, 2018

(LML) ILEP Learning Guides

Leprosy Mailing List – May 21,  2018

Ref.:    (LML) ILEP Learning Guides

From:  Annick Mondjo, Libreville, Gabon


Dear Pieter Schreuder,

 

In response to Dr. Paul Saunderson's first question on May 8, 2015, on the topic of the ILEP Learning Guides. I still got a working CD about Technical Publications (October 2005) called "ILEP Books". The total volume occupied by the files is 28.5 MB, of which 28.3 MB  for the fold of 93 pdf files in four languages (Français, English, Español, Português)

 

A zip file pdf will be sent separately in a second e-mail

I hope that it should meet the expectations of some colleagues and/or programmes.

 

Best regards


Dr Annick Mondjo

Directeur du Programme de Lutte

contre les Maladies Infectieuses

Ministère de la Santé et de la Famille

BP 50 Libreville

GABON


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


Wednesday, May 16, 2018

(LML) ILEP Learning Guides

Leprosy Mailing List – May 16,  2018

Ref.:    (LML) ILEP Learning Guides

From:  Verónica Mas, Fontilles, Spain


 Dear Colleagues,

 

The PDFs of ILEP Learning Guides are available in Spanish through Infolep. These are the titles:

·  ILEP Guía de Aprendizaje uno: Cómo diagnosticar y tratar la lepra. International Federation of Anti-Leprosy Associations. Londres: Federación Internacional de Asociaciones contra la Lepra (ILEP); 2002.

·  ILEP Guía de Aprendizaje dos: Cómo reconocer y tratar las reacciones leprosas. International Federation of Anti-Leprosy Associations. Londres: Federación Internacional de Asociaciones contra la Lepra (ILEP); 2003.

·  ILEP Guía de Aprendizaje tres: Procedimiento para efectuar una basciloscopia para la lepra. Groenen G, Saunderson PP, Ji B. Londres: Federación Internacional de Asociaciones contra la Lepra (ILEP); 2003.

·  ILEP Guía de Aprendizaje cuatro: Cómo prevenir las discapacidades en la lepra. International Federation of Anti-Leprosy Associations, Torres P. Londres: Federación Internacional de Asociaciones contra la Lepra (ILEP); 2006.

·  OMS/ILEP Guía Técnica de rehabilitación comunitaria y lepra: afrontando las necesidades de rehabilitación de las personas afectades de lepra y promocionando su calidad de vida. International Federation of Anti-Leprosy Associations. Londres: ILEP, OMS; 2007.

Kind regards,

Verónica Mas

Medical Library, Fontilles (Spain)

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


Tuesday, May 15, 2018

(LML) Are there any systematic reviews or evaluations of toolkits for challenging stigma?


Leprosy Mailing List – May 15,  2018

Ref.:    (LML)  Are there any systematic reviews or evaluations of toolkits for challenging stigma?

From:  Wim van Brakel, Amsterdam, the Netherlands


Dear Pieter and Bassey, 

Thanks to Bassey for the LML letter of April 25, 2018 with the question: "Are there any systematic reviews or evaluations of toolkits for challenging stigma?"  Sorry for this delayed response. I don't know of any reviews of toolkits. But that is perhaps because 'toolkits' is new fashion term. In the past we just called these 'interventions'. And there are plenty of reviews regarding stigma interventions, but I imagine you are familiar with most of these. You are right that evidence on effectiveness is still scarce.

The few reviews I know of are:

Leprosy:

Heijnders, M L, and S Van der Meij. 2006. "The Fight against Stigma: An Overview of Stigma-Reduction Strategies and Interventions." Psychol.Health Med. 11 (1354–8506

Cross, H A, M L Heijnders, A K Dalal, S Sermrittirong, and S Mak. 2012a. "Interventions for Stigma Reduction – Part 1: Theoretical Considerations." Disability, CBR & Inclusive Development 22 (3).

Cross, H A, M L Heijnders, A Dalal, S Sermrittirong, and S Mak. 2012b. "Interventions for Stigma Reduction – Part 2: Practical Applications." Disability, CBR & Inclusive Development 22 (3):71–80.

Sermrittirong, S, W H van Brakel, J F G Bunders, G Unarat, and P Thanyakittikul. 2014. "The Effectiveness of De-Stigmatising Interventions." International Journal of Tropical Disease & Health 4 (12):1218–32.

NTDs:

Hofstraat, K, and W H van Brakel. 2016. "Social Stigma towards Neglected Tropical Diseases: A Systematic Review." International Health 8 (suppl 1):i53–70

Mental health:

Thornicroft, G, N Mehta, S Clement, S Evans-Lacko, M Doherty, D Rose, M Koschorke, R Shidhaye, C O'Reilly, and C Henderson. 2016. "Evidence for Effective Interventions to Reduce Mental-Health-Related Stigma and Discrimination." The Lancet 387 (10023):1123–32

HIV:

Stangl, A L, J K Lloyd, L M Brady, C E Holland, and S Baral. 2013. "A Systematic Review of Interventions to Reduce HIV-Related Stigma and Discrimination from 2002 to 2013: How Far Have We Come?" J Int AIDS Soc 16 (3 Suppl 2):18734

TB:

Sommerland, N, E Wouters, E M H Mitchell, M Ngicho, L Redwood, C Masquillier, R Van Hoorn, S Van Den Hof, and A Van Rie. 2017. "Evidence-Based Interventions to Reduce Tuberculosis Stigma: A Systematic Review." INT J TUBERC LUNG DIS 21 (11):81–86

We are currently working under coordination of the NIH on a series of papers and reviews on health-related stigma that also include interventions. But these will not be available until later this year. 

I hope this helps!

With kind regards,

 

Wim


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


Monday, May 14, 2018

(LML) ILEP Learning Guides

Leprosy Mailing List – May 14,  2018

Ref.:    (LML) ILEP Learning Guides

From:  Henk Eggens, Santa Comba Dão, Portugal


 

Dear Pieter,

 

I also like to read old books. But guidelines should be as updated as possible.

Below is a list of ILEP publications and the years of their appearances. Most are over ten years old!

 

I think we should encourage ILEP to start the process of updating their excellent, but somewhat outdated guides.

 

Not only is this necessary because of the upcoming new WHO MDT regimen that were announced earlier this year. After the official WHO publication of these MDT guidelines, most country programmes will adopt these WHO guidelines sooner or later, I presume. This will have implications for rewriting some of the ILEP guides.

Moreover, it seems to me that, in the recent ten years or so, valuable lessons were learned in many aspects of clinical leprosy, leprosy control and related problems. These new insights also warrant an update of the guidelines.

 

Best regards,

 

Henk Eggens

 

 

ILEP Technical guides

----------------

Guidelines for the social and economic rehabilitation of people affected by leprosy, 1999

Facilitating the integration process, 2003

Stages and steps in the integration process, 2003

Training in leprosy, 2003

 

 

ILEP Learning guides

---------------

1: How to diagnose and treat leprosy, 2001

2: How to recognise and manage leprosy reactions, 2002

3: How to do a skin smear examination for leprosy, 2003

4: How to prevent disability in leprosy, 2006

 

 

ILEP Stigma guidelines

-----------------

1: What is health-related stigma? 2011

2: How to assess health-­related stigma, 2011

3: A roadmap to stigma reduction: an empowerment intervention, 2011

4: Counselling to reduce stigma, 2011

 

 

Other ILEP publications

-----------------------

The interpretation of epidemiological indicators in leprosy, 2001

Technical guide on community-based rehabilitation and leprosy (WHO/ILEP), 2007

Triple Jeopardy: Tackling the discrimination facing girls and women with leprosy, 2015

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 


Sunday, May 13, 2018

(LML) World Leprosy Day 2018: How forward respecting the past?

Leprosy Mailing List – May 13,  2018

Ref.:  (LML)   World Leprosy Day 2018: How forward respecting the past?

From:  Ben Naafs, Munnekeburen, the Netherlands


 

Dear Pieter,

 

The Indian Journal of Medical Research invited me to write an editorial on the occasion of World Leprosy Day 2018. Beside feeling honoured and doubting my capability to do so, I felt it would give me the opportunity to voice my reflections on leprosy.

 

What I did not write is that we, as "leprologists", should consider whether it is reasonable to "treat" the 80% who cannot develop the disease, simply because they are leprosy contacts. It may be a waste of resources and exposes the "treated" to a potential risk. We need to find a way to detect the 20% who can, and then decrease the risk with a BCG-like vaccination.

 

A detection of the reprogramming of the host cell may give us this possibility (reprogramming and detection of the 20% explained in the article). Perhaps by presenting this to LML it may unleash a discussion on contact "treating", which, with the present knowledge, is one of the only ways in which we can achieve something good. This would then explain many of the questions which we have not been able to answer as today.

 

 

Ben

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


Saturday, May 12, 2018

(LML) ILEP Learning Guides

Leprosy Mailing List – May 12,  2018

Ref.:    (LML) ILEP Learning Guides

From:  Chris Schmotzer, Rawalpindi, Pakistan


Dear Pieter,

This is in reply to the queries raised by Paul Saunderson.

We are using the print copies of the ILEP Learning Guides a lot for leprosy training in dermatology.

We would be very grateful, if a CD with HD graphics for printing would be available as the quality of printing from the online source is not very good.

Kind regards,

Dr. Chris Schmotzer

Info.alp@alp.net.pk

 

Note Editor LML:

The ILEP Learning Guides have been translated in several languages as far as I know. For sure in Portugues (Brazil) as I was involved myself. I thought also in French (but I am not sure). If new editions of the ILEP Learning Guides are planned, attention to those guides should be given as well and new editions prepared!


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


Friday, May 11, 2018

(LML) HLA susceptibility locus for leprosy in medieval Europeans

Leprosy Mailing List – May 11,  2018

Ref.:    (LML) HLA susceptibility locus for leprosy in medieval Europeans

From:  Pieter AM Schreuder, Maastricht, the Netherlands


Dear Colleagues,

 

We like to refer to an interesting article: "Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans". Krause-Kyora B, Nutsua M, Boehme L, et al. Nat Commun. 2018 May 1;9(1):1569. doi: 10.1038/s41467-018-03857-x.

 

Abstract:

Leprosy, a chronic infectious disease caused by Mycobacterium leprae (M. leprae), was very common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval skeletons from Denmark that show lesions specific for lepromatous leprosy (LL). First, we test the remains for M. Leprae DNA to confirm the infection status of the individuals and to assess the bacterial diversity. We assemble 10 complete M. Leprae genomes that all differ from each other. Second, we evaluate whether the human leukocyte antigen allele DRB1*15:01, a strong LL susceptibility factor in modern populations, also predisposed medieval Europeans to the disease. The comparison of genotype data from 69 M. Leprae DNA-positive LL cases with those from contemporary and medieval controls reveals a statistically significant association in both instances. In addition, we observe that DRB1*15:01 co-occurs

with DQB1*06:02 on a haplotype that is a strong risk factor for inflammatory diseases today.

 

Download PDF http://www.nature.com/articles/s41467-018-03857-x.pdf

 

 

Best regards,

 

 

Pieter Schreuder

 

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com