Thursday, April 13, 2017

(LML) InfoNTD monthly mail with the latest publications on cross-cutting issues and NTDs - April 2017

Leprosy Mailing List – April 13,  2017

Ref.:  (LML) InfoNTD monthly mail with the latest publications on cross-cutting issues and NTDs - April 2017

From: Ilse Egers, Amsterdam, the Netherlands


Dear LML readers,

 

This newsletter provides you with a selection of news items and recent publications on cross-cutting issues in NTDs. Our starting point is to add articles covering a wide variety of issues. Unfortunately, this is not always possible due to a limited diversity in and shortage of articles on cross-cutting issues and NTDs.

Feel free to contact us (infontd@leprastichting.nl) with any questions or to receive the full text versions if a link to the full text is not included. Our document delivery service is free!

Kind regards,
 
Ilse Egers
InfoNTD Information officer

 

 

News

 

 

Togo: first country in sub-Saharan Africa to eliminate lymphatic filariasis
8 April 2017 | Brazaville | Geneva
Read more

 

 

New publications

 

 

A study on morbidity management among lymphatic filariasis patients in Udupi district, Karnataka, India.
Basavaraj K, Bharatesh SK, Murali D et al. International Journal of Medicine and Public Health. 2017; 7(2).
Abstract Among 178 LF patients only about 34% had knowledge about the disease causation. About 98.3% had good hygiene practice towards affected area but only 30% of them regularly practiced one or the other exercise as recommended. The study clearly indicates the outreach focus on LF patients needs to be enhanced by grass root level health workers. The program has to ensure that all the LF patients will undergo morbidity management training and know how to take care of lymphoedema.
Read more


The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals.
Bangert M, Molyneux DH, Lindsay SW et al. Infect Dis Poverty. 2017; 6(1):73.
Abstract The Sustainable Development Goals (SDGs) call for an integrated response, the kind that has defined Neglected Tropical Diseases (NTDs) efforts in the past decade.NTD interventions have the greatest relevance for SDG3, the health goal, where the focus on equity, and its commitment to reaching people in need of health services, wherever they may live and whatever their circumstances, is fundamentally aligned with the target of Universal Health Coverage.
Download PDF


A randomised controlled trial to evaluate the effect of a new skin care regimen on skin barrier function in those with podoconiosis in Ethiopia.
Brooks J, Ersser SJ, Cowdell F, Gardiner E et al. British Journal of Dermatology. 2017.
Abstract To evaluate the effectiveness of a new, low-cost, evidence-based intervention to improve SBF in the lower limbs of those with podoconiosis. Improvement in SBF was observed in both groups across all measurement sites and time points, although this was significantly greater in the experimental group.
Read more


Cultural validation of a new instrument to measure leprosy-related stigma: the SARI Stigma Scale.
Dadun, Peters RMH, Van Brakel WH et al. Lepr Rev. 2017: 88(1):23-42.
Abstract Due to the many adjustments we decided to rename the instrument to SARI Stigma Scale. The scale is comprehensive, reliable and culturally valid to assess four aspects of stigma among persons affected by leprosy in a setting like Cirebon District. Further research will determine whether this instrument is valid in other settings, cultures and with other neglected tropical diseases.
Download PDF


A multidisciplinary, integrated approach for the elimination of schistosomiasis: a longitudinal study in a historically hyper-endemic region in the lower reaches of the Yangtze River, China from 2005 to 2014.
Sun L-P, Wang W, Zuo Y-P et al. Infect Dis Poverty. 2017; 6(1):56.
Abstract A three-step roadmap for schistosomiasis elimination was designed in the study site, and multidisciplinary, integrated interventions were implemented by the health, agriculture, water resources development, land and resources, and forestry sectors from 2005 to 2014, including chemotherapy for infected individuals, health education, management of the source of Schistosoma japonicum infection, and intermediate host snail control. The results of the present 10-year longitudinal study demonstrate that the multidisciplinary, integrated approach is effective for the elimination of schistosomiasis as a public health problem in the lower reaches of the Yangtze River, China.
Download PDF


Soil transmitted helminthiasis in indigenous groups. A community cross sectional study in the Amazonian southern border region of Ecuador.
Romero-Sandoval N, Ortiz-Rico C, Sánchez-Pérez HJ et al. BMJ open. 2017; 7:e013626.
Abstract At the individual level, the prevalence of geohelminth infection reached 46.9%, with no differences in terms of gender, age, temporary migration movements or previous chemoprophylaxis. In 72.9% of households, one or more members were infected. Receiving subsidies and overcrowding were associated with the presence of helminths. The prevalence of geohelminth infection was high. Our study suggests that it is necessary to conduct studies focusing on communities, and not simply on captive groups, such as schoolchildren, with the object of proposing more suitable and effective strategies to control this problem.
Download PDF


Environmental risk factors for the incidence of cutaneous leishmaniasis in an endemic area of Iran: a GIS-based approach.
Ramezankhani R, Hosseini A, Sajadi N et al. Spatial and Spatio-temporal Epidemiology. 2017.
Abstract OLS revealed a significant correlation between CL incidence and five predictors including temperature, population density, wind speed, humidity and NDVI; which explained 28.6% of variation in CL incidence in the province. Considering AICc and adjusted R2, GWR provided a better fit to the data compared with OLS. There was a positive correlation between temperature and population density with CL incidence in both local (city) and global (province) level.
Read more


Schistosomiasis is more prevalent than previously thought: what does it mean for public health goals, policies, strategies, guidelines and intervention programs?
Colley DG, Andros TS, Campbell CH. Infect Dis Poverty. 2017; 6(1):63.
Abstract New mapping tools based on detection of worm antigens in urine of those infected are highly sensitive and the CAA assay is reported to be highly specific. Using these tools in areas of low prevalence of all three of these species of schistosomes has demonstrated that more people harbor adult worms than are regularly excreting eggs at a level detectable by the usual stool assay or by urine filtration. In very low prevalence areas this is sometimes 6- to10-fold more. There is also a critical need for new guidelines based on the use of these more sensitive assays for those national NTD programs that wish to move forward to strategies designed for elimination.
Download PDF


Modelling the health and economic impacts of the elimination of river blindness (onchocerciasis) in Africa.
Kim YE, Stolk WA, Tanner M et al. BMJ Global Health. 2017; 2:e000158.
Abstract We estimated the health benefits using a dynamical transmission model, and the needs for health workforce and outpatient services for elimination strategies in comparison to a control mode. We then estimated the associated costs to both health systems and households and the potential economic impacts in terms of income gains. The elimination of onchocerciasis in Africa would lead to substantial health and economic benefits, reducing the needs for health workforce and outpatient services. To realise these benefits, the support and collaboration of community, national and global policymakers would be needed to sustain the elimination strategies.
Download PDF


Impact of health education based intervention on community's awareness of dengue and its prevention in Delhi, India.
Kusuma YS, Burman D, Kumari R et al. Glob Health Promot. 2017.
Abstract This study is intended to implement health education towards prevention of dengue, and to assess its impact on people's knowledge and practices related to causes and prevention of dengue among urban poor in Delhi. Health education based intervention was carried out through partnership with the municipal bodies and non-governmental organizations. Socio-demographic characteristics of participants were similar in both surveys. Intervention resulted in significant increase in knowledge on cause, symptom perception and mosquito behaviour in terms of breeding and biting habits. Practice of personal protection measures increased significantly. The participation of people increased during intervention compared to the routine programme. Health education based interventions are instrumental in improving people's knowledge and behaviour. Hence, routine health educational activities as a supportive strategy in the health system need to be strengthened.
Read more


A cross sectional study to assess perception regarding mosquito borne diseases in urban areas of Belagavi city.
Kulkarni RR, Biradar MK. International Journal of Community Medicine and Public Health. 2017; 4(4):1039-1042.
Abstract Data was collected by systemic random sampling. Data was compiled, tabulated and analyzed using proportions. Out of 360 participants 78.33% knew about mosquitoes borne diseases, 31.3 % people had the knowledge that mosquitoes can cause malaria, dengue and chikungunya, 36.6% consider drainage and garbage as common breeding place. 57.8% people use mosquito coils to prevent mosquito bite. 61.4% had knowledge about disease through TV and newspapers. Lack of awareness and knowledge about mosquito borne disease in low socio economic status and illiterates and also about breeding sites of mosquitoes.
Download PDF


Active trachoma and community use of sanitation, Ethiopia.
King D, Emerson PM, Callahan EK et al. WHO Bulletin. 2017; 95:250-260.
Abstract In Amhara, Ethiopia, a negative correlation was observed between community sanitation usage and prevalence of active trachoma among children, highlighting the need for continued efforts to encourage higher levels of sanitation usage and to support sustained use throughout the community, not simply at the household level.
Download PDF


Interdisciplinary approach at the primary healthcare level for Bolivian immigrants with Chagas disease in the city of São Paulo.
Shikanai Yasuda MA, Sátolo CG, Carvalho NB et al. PLoS Negl Trop Dis. 2017; 11(3):e0005466.
Abstract An interdisciplinary approach including antiparasitic treatment is feasible at the primary healthcare level for the management of Chagas disease in Bolivian immigrants. The itinerant feature of immigration was associated with a lack of adherence to antiparasitic treatment and was considered a main challenge for the clinical management of this population. This approach is recommended for management of the infected population in endemic and nonendemic areas, although different strategies are needed depending on the severity of the disease and the structure of the healthcare system.
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Knowledge, practices and perceptions of geo-helminthes infection among parents of pre-school age children of Coastal region, Kenya.
Masaku J, Mwende F, Odhiambo G et al. PLoS Negl Trop Dis. 2017; 11(3):e0005514.
Abstract Our results show that to a large extent the parents of the pre-school age children have information on worm infections. However, some cultural beliefs and practices on the pathology and mode of transmission mentioned could be a hindrance to prevention and control efforts. There is need to implement health promotion campaigns to strengthen the impact of control strategies and reduce infection.
Download PDF


Mapping the dengue scientific landscape worldwide: a bibliometric and network analysis.
Mota FB, Galina AC, da Silva RM. SciELO Brasil. 2017.
Abstract Despite the current global trend of reduction in the morbidity and mortality of neglected diseases, dengue’s incidence has increased and occurrence areas have expanded. Dengue also persists as a scientific and technological challenge since there is no effective treatment, vaccine, vector control or public health intervention. Combining bibliometrics and social network analysis methods can support the mapping of dengue research and development (R&D) activities worldwide. The aim of this paper is to map the scientific scenario related to dengue research worldwide. Our results show a significant increase of dengue publications over time.
Download PDF


Water, Sanitation and Hygiene (WASH) and environmental risk factors for soil-transmitted helminth intensity of infection in Timor-Leste, using real time PCR.
Campbell SJ, Nery SV, Wardell R et al. PLoS Negl Trop Dis. 2017; 11(3):e0005393.
Abstract In this high-prevalence setting, strong risk associations with environmental factors indicate that anthelmintic treatment alone will be insufficient to interrupt STH transmission, as conditions are favourable for ongoing environmental transmission. Integrated STH control strategies should be explored as a priority.
Download PDF


Joint effects of climate variability and socio-ecological factors on dengue transmission: Epidemiological evidence.
Akter R, Hu W, Naish S et al. Trop. Med. Int. Health. 2017.
Abstract Following PRISMA guidelines, a detailed literature search was conducted in PubMed, Web of Science and Scopus. Peer-reviewed, freely available and full text articles, considering both climate and socio-ecological factors in relation to dengue, published in English from January 1993 to October 2015 were included in this review. Due to insufficient data, methodological issues, and contextual variability of the studies it is hard to draw conclusion on the joint effects of climate variability and socio-ecological factors on dengue transmission. Future research should take into account socio-ecological factors in combination with climate variables for a better understanding of the complex nature of dengue transmission as well as for improving the predictive capability of dengue forecasting models, to develop effective and reliable early warning systems.
Download PDF


Building a global schistosomiasis alliance: an opportunity to join forces to fight inequality and rural poverty.
Savioli L, Albonico M, Colley DG et al. Infect Dis Poverty. 2017; 6(1):65.
Abstract The Global Schistomiasis Alliance (GSA) aims to be a partnership of endemic countries, academic and research institutions, international development agencies and foundations, international organizations, non-governmental development organizations, private sector companies and advocacy and resource mobilisation partners. Ultimately, the GSA calls for a partnership to work for the benefit of endemic countries by addressing health inequity and rural poverty.
Download PDF


An ethnobotanical survey of traditional medicinal plants used against lymphatic filariasis in South Africa.
Komoreng L, Thekisoe O, Lehasa S et al. South African Journal of Botany. 2017; 111:12-16.
Abstract The respondents were asked questions regarding their use of medicinal plants to treat lymphatic filariasis and related ailments. Information entailing plants used to treat lymphatic filariasis, plant parts used, mode of preparation and dosage was recorded. The information collected revealed 46 medicinal plants belonging to 28 families were used against lymphatic filariasis. It was interesting to note that different traditional healers from the four Provinces use similar plants to treat lymphatic filariasis. The most prominent methods of herbal administration used were orally and soaking of the affected body part. This study has documented important ethnobotanical information on medicinal plants used by South African healers and indigenous people in the treatment of lymphatic filariasis and related diseases.
Read more


Will a new 2017 global leadership commit to NTDs?
Hotez PJ, Aksoy S. PLoS Negl Trop Dis. 2017; 11(3):e0005309.
Download PDF


Chronic venous leg ulcer care–are we missing a vital piece of the jigsaw?
Green J, Jester R, McKinley R et al. Wounds UK. 2017; 13:30-37.
Abstract This project explored the lived experiences of patients with leg ulcers to ascertain the impact on their quality of life. Several key themes were identified including the dominance of pain. Observations revealed that issues emphasised as important by participants, were not raised during consultations. The results of this study reveal that participants have concerns far beyond their actual wound care. Application of the new consultation template may go some way to redress the balance of the consultation.
Read more


Spatial risk mapping for Dengue fever using GIS: A case study of Hyderabad.
Panhwer MA, Pirzada N, Abro A et al. Sindh University Research Journal. 2017; 49(1):43-46.
Abstract There is compelling evidence that changes in the climate of the earth occur which cannot be explained without taking into account human influence. Many vulnerability studies anticipate climate change will lead to increased occurrence of transmittable diseases, including Vector Borne Diseases (VBDs). This study used GIS application to identify areas prone tosuch diseases. The results show that Latifabad is a major area prone to VBD followed by Bhitainagar, Qasimabad and Heerabad. The ability to identify likely areas of dengue incidence helps for quick and efficient disease supervision and prevention practices.
Download PDF


Applying a mobile survey tool for assessing lymphatic filariasis morbidity in Mtwara Municipal Council of Tanzania.
Mwingira UJ, Downs P, Uisso C et al. mHealth. 2017; 3.
Abstract A number of methods have been used to estimate lymphatic filariasis (LF) morbidity, including: routine programmatic data, cluster random surveys and the “town crier” method. Currently, few accurate data exist on the global LF morbidity burden in Tanzania. We aimed to estimate prevalence of lymphedema and hydrocele in Mtwara Municipal Council using mobile phone based survey. The findings suggest that mobile phone based surveys are a practical approach of undertaking morbidity surveys.This approach can be expected to encourage identification of lymphedema and hydrocele morbidity at community level and provide evidence where further morbidity surveys are warranted.
Read more


 

 

Events

 

 

Global Partners Meeting on NTDs
The World Health Organization (WHO) will host a Global Partners Meeting on Neglected Tropical Diseases (NTDs) on 19 April 2017.
Read more
 
NTD Summit 2017
19 to 22 April 2017 | Geneva, Switzerland
2017 marks the 5th anniversary of the World Health Organization's roadmap on NTDs and the London Declaration. To celebrate this milestone, Uniting to Combat NTDs, the World Health Organization and the NTD community are hosting the NTD Summit in Geneva, Switzerland in April 2017.
Read more

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

 


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Wednesday, April 12, 2017

(LML) LML blog link: http://leprosymailinglist.blogspot.it/

Leprosy Mailing List – April 12,  2017

Ref.: (LML)   LML blog link: http://leprosymailinglist.blogspot.it/

From:  Pieter Schreuder, Maastricht, the netherlands


 

Dear LML reader,

 

The problems we faced in February 2017 have been solved. Nevertheless, I would strongly advise to have a look at our blog once a while.

 

For example, Dr. Dinkar D. Palande  and Dr. Sunil Deepak have produced a pdf file based on slides of Dr. Palande namely “Nerve Surgery in Leprosy”. You will find this pdf file on our blog, but you could also access it be downloaded from the LML archives at the following link: http://english.aifo.it/leprosy/mailing_list/2017/Nerve_surgery_in_leprosy_Dinkar_Palande01.pdf

 

For those who joined LML more recently: LML is an e-mail based forum for exchange of information, mutual support, training and discussions on leprosy among persons based in different countries and continents. It runs at a volunteer level for more than fifteen years. With gradual decrease in incidence of leprosy and leprosy related expertise in many parts of the world, perhaps its most important role is for supporting persons working in leprosy control and rehabilitation in low endemic situations.  

 

LML was started by Dr. Salvatore Noto. Since 2006, the archives of LML are hosted by the website of “Associazione Italiana Amici di Raoul Follereau” (AIFO), in Bologna, Italy. AIFO also manages the leprosy mailing list blog that publishes all messages circulated on LML. All the archives of LML, including attached documents are freely consultable. Today four persons are involved in the running, on a voluntarily basis, of this initiative, namely Sunil Deepak, from India, Bernard Naafs, from the Netherlands, Salvatore Noto from Italy and Pieter Schreuder from the Netherlands. Pieter Schreuder is presently the chief editor.

 

Objectives and Functioning

The specific objectives of the LML are: 1) divulge information about leprosy, its causes, prevention and treatment; 2) share information about management of leprosy control activities and programmes; 3) share information about socio-cultural aspects of leprosy and rehabilitation of patients with disabilities; 4) offer a distance learning tool in leprosy for health professionals; and 5) create a forum to discuss the main issues on leprosy and its control activities and programmes.

 

Contributions like papers, clinical cases, letters, comments, reports etc. are sent to the moderator via e-mail, who edits them in a common format and are then circulated among the members. Often prior to circulation of the documents, there is an exchange of opinions between the moderator and the contributor, to clarify or modify points that are not clear.

 

LML is not only a forum for those still active in the field of leprosy, but it also offers the opportunity to those not active in the field of leprosy anymore, but who have a wide and valuable experience to share. In this way contributing to the education of their young successors.


Anyone is welcome to contribute to our LML forum. Any contribution or opinion is welcome as long as that can be supported or corroborated, preferably by references from literature.

 

 

Best wishes,

 

 

Pieter AM Schreuder


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


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Monday, April 10, 2017

(LML) NLEP Newsletter October-December 2016, Vol. 1, issue 5

Leprosy Mailing List – April 10,  2017

Ref.:  (LML)  NLEP Newsletter October–December 2016, Vol. 1, issue 5

From:  Anil Kumar, New Delhi, India


 

Dear All,

Greetings for the time being.

We are pleased to share hereby the Vol. 1, Issue 5 of NLEP Newsletter, the soft copy of which is attached herewith for your ready reference.

Further, same may be accessed at the link given below
http://nlep.nic.in/pdf/NLEP%20Newsletter%20Oct-%20Dec%20%202016-%20%20English.pdf

With hope that you find this newsletter useful, this division look forward for your feedback.

Best regards,

Dr. Anil Kumar

DDG(L)


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


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Sunday, April 9, 2017

(LML) AZALEP trial

Leprosy Mailing List – April 9,  2017

Ref.:    (LML)  AZALEP trial

From:  Joel Almeida, Mumbai and London


 

 

Dear Pieter,

 

A randomised controlled double blind trial (Lockwood et al, 2017) compared prednisolone alone with prednisolone + azathioprine, for nerve damage in leprosy. It was designed and done with reasonable care, and the analysis was on an "Intention To Treat" basis.

 

This study understandably omitted a comparison between prednisolone and placebo. Probably because that comparison had already been made in a randomised double-blind controlled trial or RCT (van Brakel et al, 2003).

 

In that earlier RCT, prednisolone had a protective effect on sensory scores, compared to placebo, at the end of 4 months of treatment. The RCT demonstrated a risk ratio of 2.58 for worsened scores in the placebo group between the start and end of treatment (confidence interval 1.19 to 5.60). Therefore prednisolone does have a demonstrable protective effect on sensory scores.

 

Given those findings, omission or neglect of prednisolone would be unethical in trials or in treatment of nerve damage in leprosy. The AZALEP study understandably did not have a placebo-only group. However, in the absence of a placebo-only group, the report is not well placed to assert a lack of effect for prednisolone, as it appears to do in places. The report appears otherwise reliable.

Prednisolone had already been demonstrated to have a protective effect on sensory scores in nerve function impairment (NFI) in leprosy, when NFI was detected sufficiently early.

 


Joel Almeida

 

References

1. Diana N. J. Lockwood , Joydeepa Darlong, Pitchaimani Govindharaj, Royce Kurian, Pamidipani Sundarrao, Annamma S. John. AZALEP a randomized controlled trial of azathioprine to treat leprosy nerve damage and Type 1 reactions in India: Main findings. PLOS NTD. Published: March 30, 2017 http://dx.doi.org/10.1371/journal.pntd.0005348

 

2. Van Brakel WH, Anderson AM, Withington SG, Croft RP, Nicholls PG, Richardus JH, Smith WC. The prognostic importance of detecting mild sensory impairment in leprosy: a randomized controlled trial (TRIPOD 2). Lepr Rev. 2003 Dec;74(4):300-10.


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com



 


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Thursday, April 6, 2017

(LML) Infolep monthly overview of new publications on leprosy - April 2017

Leprosy Mailing List – April 6 ,  2017

Ref.: (LML)   Infolep monthly overview of new publications on leprosy - April 2017

From:  Jiske Erlings, Amsterdam, the Netherlands


Dear friends and colleagues, 
 
Below you will find a selection of recent publications on leprosy. Feel free to contact me (
infolep@leprastichting.nl) to receive the full text versions if a link to the full text is not included or for assistance with your literature research. You are also invited to send us your publications on leprosy or material on leprosy in your language to include in the portal.

With kind regards,
 
Jiske Erlings
Infolep Information specialist

 

 

Highlighted publications

 

 

New issue Leprosy Review: https://www.lepra.org.uk/Pages/FAQs/Category/volume-88

WHO Leprosy Factsheet - Update February 2017
English 

International textbook of leprosy.
Scollard DM, Gillis TP. American Leprosy Missions. 2016.

Now online - with new chapters!

 

 

New publications

 

 

Nerve Damage in Young Patients with Leprosy Diagnosed in an Endemic Area of the Brazilian Amazon: A Cross-Sectional Study.
Bandeira SS, Pires CA, Quaresma JA. J Pediatr. 2017 Mar 9.
Read abstract


Primary Cutaneous Histoplasmosis Masquerading as Lepromatous Leprosy.
Bhattacharya JB, Rani P, Aggarwal R, et al. J Clin Diagn Res. 2017 Jan;11(1):ED01- ED02.
Download PDF


Forecasting the new case detection rate of leprosy in four states of Brazil: A comparison of modelling approaches.
Blok DJ, Crump RE, Sundaresh R, et al. Epidemics. 2017 Mar;18:92-100.
Read abstract


Survey of Random Blood Sugar Levels Amongst Leprosy-disabled People in Bangladesh.
Butlin C R, Hossain D, Singh S, et al. Bangl J Medic. 2017; 28(1).
Read PDF


Venous thrombo-embolism. Thalidomide & Leprosy.
Chhabria BA, Pannu AK, Bhalla A. QJM. 2017 Mar 11.
Read PDF


Analysis of a novel multiplex polymerase chain reaction assay as a sensitive tool for the diagnosis of indeterminate and tuberculoid forms of leprosy.
Chaitanya VS, Cuello L, Das M, et al. Int J Mycobacteriol. 2017 Jan-Mar;6(1):1-8.
Download PDF


Association of Nitric Oxide Synthase2 gene polymorphisms with leprosy reactions in northern Indian population.
Dubey A, Biswas SK, Sinha E, et al. Infect Genet Evol. 2017 Mar 15.
Read abstract


Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction.
Fava VM, Sales-Marques C, Alcaïs A, et al. Front Immunol. 2017 Feb 14;8:155.
Download PDF 


Genomic characterization of Nontuberculous Mycobacteria.
Fedrizzi T, Meehan CJ, Grottola A, et al. Sci Rep. 2017 Mar 27;7:45258.
Download PDF


Will a new 2017 global leadership commit to NTDs?
Hotez PJ, Aksoy S.  PLoS Negl Trop Dis. 2017 Mar 23;11(3):e0005309.
Download PDF


Characterization of miRNAs expression profiles and identification of potential biomarkers in leprosy.
Jorge KT, Souza RP, Assis MT, et al. J Clin Microbiol. 2017 Mar 8.
Read abstract


Multifaceted role of lipids in Mycobacterium leprae.
Kaur G, Kaur J. Future Microbiol.
2017 Mar;12:315-335.
Read abstract


Borderline Lepromatous Leprosy, Erythema Nodosum Leprosum and a generalized Varicella Zoster Virus infection.
Kennedy C, Naafs B. J Eur Acad Dermatol Venereol. 2017
Read abstract


Clinical Presentation and Histopathology of Childhood Leprosy.
Kumaravel S, Murugan S, Fathima S, et al. Int J Sci Stud 2017;4(11):167-169.
Download PDF


AZALEP a randomized controlled trial of azathioprine to treat leprosy nerve damage and Type 1 reactions in India: Main findings.
Lockwood DN, Darlong J, Govindharaj P, et al. PLoS Negl Trop Dis. 2017 Mar 30;11(3):e0005348.
Download PDF


Lucio's phenomenon: exuberant case report and review of Brazilian cases.
Rocha RH, Emerich PS, Diniz LM, et al. An Bras Dermatol. 2016 Sep-Oct;91(5 suppl 1):60-63.
Download PDF


Polymorphisms in genes TLR1, 2 and 4 are associated with differential cytokine and chemokine serum production in patients with leprosy.
Mem Inst Oswaldo Cruz. 2017 Apr;112(4):260-268.
Download PDF


International open trial of uniform multidrug therapy regimen for leprosy patients: Findings & implications for national leprosy programmes.
Manickam P, Mehendale SM, Nagaraju B, et al. Indian J Med Res. 2016 Oct;144(4):525-535.
Download PDF


Histoid leprosy: a retrospective clinicopathological study from central Nepal.
Mathur M, Jha A, Joshi R, et al. Int J Dermatol. 2017 Mar 21.
Read abstract


Vitamin D Receptor Expression and Hepcidin Levels in the Protection or Severity of Leprosy: a Systematic Review.
de Oliveira AL, Chaves AT, Menezes CA, et al.
Microbes Infect. 2017 Mar 16. pii: S1286-4579(17)30039-4.
Read abstract


A tale of two neglected tropical infections: using GIS to assess the spatial and temporal overlap of schistosomiasis and leprosy in a region of Minas Gerais, Brazil.
Phillips DA, Ferreira JA, Ansah D, et al. Mem Inst Oswaldo Cruz. 2017 Apr;112(4):275-280.
Download PDF


A Systematic Review of Immunological Studies of Erythema Nodosum Leprosum.
Polycarpou A, Walker SL, Lockwood DN. Front Immunol. 2017 Mar 13;8:233.
Download PDF


Leprosy: Trophic Skin Ulcers.
Riyaz N, Sehgal VN.
Skinmed. 2017 Feb 1;15(1):45-51.
Read abstract


Uniform multidrug therapy for leprosy - time for a rethink?
Saunderson PR. Indian J Med Res. 2016 Oct;144(4):499-501.
Download PDF


sCD163 levels as a biomarker of disease severity in leprosy and visceral leishmaniasis.
Silva RL, Santos MB, Almeida PL, et al. PLoS Negl Trop Dis. 2017 Mar 29;11(3):e0005486.
Download PDF


Mycobacterium lepraemurium uses TLR-6 and MR, but not lipid rafts or DC-sign, to gain access into mouse
macrophages.

Silva-Miranda M, Arce-Paredes P, Rojas-Espinosa O. Int J Mycobacteriol.
2017 Jan-Mar;6(1):52-60.
Download PDF


Response of iNOS and its relationship with IL-22 and STAT3 in macrophage activity in the polar forms of leprosy.
de Sousa JR, de Sousa RP, de Souza Aarão TL, et al. Acta Trop. 2017 Mar 18.
Read abstract
https://www.leprosy-information.org/resource/response-inos-and-its-relationship-il-22-and-stat3-macrophage-activity-polar-forms-leprosy


Immunodominant protein MIP_05962 from Mycobacterium indicus pranii displays chaperone activity.
FEBS J. 2017 Mar 10.
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Trends in leprosy case detection in Rwanda, 1995–2011: analysis of 17 years of laboratory data.
Uwimana I, Bizimungu N, Ingabire F. African Journal of Laboratory Medicin.
2017.
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Borderline Tuberculoid leprosy masquerading as granuloma annulare: A clinical and histological pitfall.
Zhu TH, Kamangar F, Silverstein M, et al. Am J Dermatopathol. 2017 Apr;39(4):296-299.
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Journals & Newsletters

 

 

Community Eye Health Journal: http://www.cehjournal.org/

Disability, CBR & Inclusive Development: http://dcidj.org/

Hansenologia Internationalis: http://www.ilsl.br/revista/atual.php

Indian Journal of Leprosy: http://www.ijl.org.in/index.html 

Leprosy Review: https://www.lepra.org.uk/Pages/FAQs/Category/volume-88
Leprosy Review Repository (1928-2001) : http://leprev.ilsl.br/arquivo.php

Plos Neglected Tropical Diseases: http://journals.plos.org/plosntds/
 
Revista de Leprología:
http://www.leprosy-information.org/resource/revista-de-leprologia
 
WHO Goodwill Ambassador’s Newsletter for the elimination of leprosy:
http://www.leprosy-information.org/resource/who-goodwill-ambassador-s-newsletter-elimination-leprosy 

 

 

Websites & Services

 

 

InfoNTD - Information on cross-cutting issues in Neglected Tropical Diseases (NTDs) https://www.infontd.org/

LML - Leprosy Mailing List - a free moderated email list that allows all persons interested in this theme to share ideas, information, experiences and questions.
http://leprosymailinglist.blogspot.nl/


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 


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