Monday, April 15, 2013

The leprosy burden - Monitoring national trends would be “better”


Ref.:   The leprosy burden - Monitoring national trends would be “better”.
From: D Soutar, London, UK

  
Dear Salvatore,

With regard to your recent posting of May 8th, 2012.  The comparison of trends in New Case detection and Prevalence are interesting but as to your question of “which is better?” I would suggest that the question should be focused more on which (if any) is more ‘meaningful or more useful’ in terms of operational effectiveness of leprosy control programmes?  The key difficulty in looking at these global trends, whether with or without India, is how to interpret them in ways that have some practical and operational meaning for leprosy programme managers, field workers and ultimately for people affected.

In recent years there has been much written about the value and reliability, or otherwise, of ‘global’ leprosy data.  As the overall prevalence of leprosy has declined dramatically, the focus has naturally shifted towards reporting actual numbers of new cases detected in countries and even more importantly, the numbers of people detected who already have leprosy related impairments and disabilities.  Looking at the geography of leprosy and trends in specific countries is a much more useful endeavour when thinking about how to sustain effective leprosy services.  Thus, while the annual publication of global data in the WER is still useful for gaining an overall global picture, those WERs which have focused on the trends of leprosy within specific countries have been much more useful and practical when trying to understand what is happening to leprosy at a country level and whether control is being effectively sustained and disabilities prevented.  Good examples of country-specific WERS in recent years include those on Indonesia, China, Yemen, Thailand and Vietnam.  These can all be found at http://www.ilep.org.uk/library-resources/wers-on-leprosy/2001-2010/ .  Similar country specific reports on Brazil and India would be most interesting given the continuing high caseloads in those countries.

With the achievement of global elimination as a public health problem in 2000, and the fact that the majority of countries have also achieved this goal, the emphasis has shifted more towards the recording of new cases, treatment completion rates and the reduction of leprosy related disabilities, stigma and discrimination.  The WHO’s Enhanced Global Strategy set the target of reducing the rate of Grade 2 disability in new cases by 35% between 2011 and 2015.  Monitoring national trends on these indicators would be “better” and more useful from an operational perspective than the global trends of either prevalence or incidence.

With best regards,
Douglas Soutar
Douglas Soutar
General Secretary
International Federation of Anti-Leprosy Associations
Tel: 44 (0) 207 602 69 25 – Fax:  44 (0) 207 371 16 21 – Website: www.ilep.org.uk
E-mail: doug.soutar(at)ilep.org.uk

Request of information about a tool designed to measure and monitor ulcers


Ref.:   Request of information about a tool designed to measure and monitor ulcers.
From: D Andersen, Chennai, India

  

Dear Dr Salvatore,

Thank you for adding me to the mailing list.  I am a student at Brigham Young University in the U.S. and I am conducting an internship with a leprosy rehabilitation organization called Rising Star Outreach; they operate outside of Chennai in India.

I am currently seeking a tool designed to measure and monitor ulcers.  I am evaluating an organizations health services which includes a mobile medical clinic that visits leprosy colonies bi-weekly to provide any treatments, as well as training and supplies for self-care.  So, the tool needs to be sensitive enough to measure the impact their programs have on the treatment of ulcers.  Any direction for finding such a resource would be greatly appreciated.

Thanks,

Dane Andersen
Project Evaluation and Assessment Team
Brigham Young University

R.I.P. Dr CK Job


Ref.:   R.I.P. Dr CK Job
From: H. Srinivasan, Chennai, India



Dear Dr Salvatore Noto and my LML friends,
I was shocked to learn that Dr. CK Job passed away two weeks ago, on 26th May.  I understand he was 89 years old at the time of his death, but more than with anybody else in his case particularly, age is no valid excuse nor does it justify one’s passing away.  As I am getting older I find I am getting more and more lonely as my friends are gradually disappearing from the scene, one by one; Drs. Christian, Ramu, Ramanujam, Selvapandian, Fritschi, Ganapathi . . . and now Dr. Job.  It appears that along with leprosy, the breed of dedicated leprologists is also getting “eliminated’ by time!  
We may not have been communicating with each other frequently, but there was a mental rapport amongst us, transcending language, religion and our own individual specialties.  We valued our friendship and respected the others’ industry, scholarship, integrity, simplicity and sincerity and recognized our common concern which was the well-being of the individual leprosy-affected person, irrespective of the leprosy scenario in the community at large.  Dr. Job towered above most, if not all, of us, his contemporaries, in these qualities.  He was never pompous or overbearing even when most provoked to be so, and that more than anything else endeared him to me right from the beginning.  At this juncture I can only say that I have indeed been extremely fortunate that I came to know Dr. CK Job fairly early in my career and could claim him as a friend of mine.

H. Srinivasan
Surgeon (Retired)
25, First Seaward Road
Chennai 600 041
(South India)

“Madagascar en deuil”


Ref.:   “Madagascar en deuil” [French]
From: Ralaivao-Mano S, Antananarivo, Madagascar


Bonjour à tous!

Suite à un paludisme grave (neuro-paludisme), nous avons le regret de vous affirmer que Dr NORO de la Fondation Raoul Follereau qui était avec nous lors de la formation à Bamako en février 2012, est décédé aujourd'hui le 08 juin 2012.
Prier pour elle, que son âme soit avec notre DIEU.

Dr Samuel RALAIVAO-MANO
Médecin au Service de Lutte contre la Lèpre
Responsable de suivi et évaluation
BP: 8669
ANTANANARIVO 101
MADAGASCAR



Dear All,

Following severe (cerebral) malaria, we regret to say that Dr. Noro from the Raoul Follereau Foundation, died on June 8th, 2012.
Pray for her, that her soul is with our God.

Dr.
Samuel RALAIVAO-MANO 

The diagnosis of leprosy is not always easy


Ref.:   The diagnosis of leprosy is not always easy
From: B Naafs, Munnekeburen, The Netherlands


Dear Salvatore,

I refer to last week messages about early diagnosis of lepromatous leprosy.  Kindly, find in attachment the paper of J A da Costa Nery et al. “Hansen’s disease in a general hospital: uncommon presentations and delay in diagnosisJ Eur Acad Dermatol Venereol 2009 Feb;23 (2):150-6. Epub 2008 Sep 10.  I would be very grateful if you forward it to the leprosy mailing list.

The diagnosis of leprosy is not always easy, as it is generally stated and thought. To be aware that a condition or complaint could be leprosy is a start.  As leprosy is suspected it has to be proven.  The cardinal signs of leprosy have to be investigated.  They are loss of sensation in a skin lesion, enlarged peripheral nerves and positive slit-skin smear examination (*).  When two of these three signs are positive, leprosy is diagnosed. 

Ninety nine per cent of all leprosy patients can be diagnosed in the above mentioned way.  Herewith I will say a few words about one exception (indeterminate leprosy) and, two particular conditions namely: early lepromatous leprosy and diffuse lepromatous leprosy (also called Lapati’s leprosy or “Lepra bonita”).

Indeterminate leprosy
The diagnosis of indeterminate leprosy depends on awareness. Loss of sensation is often hardly present or is absent, nerves are not enlarged and skin smear is negative.  Even biopsy may be hardly helpful.  It is “the time that makes the diagnosis” and thus careful follow-up of the patient is needed for a few months.

Early lepromatous (LL) leprosy
In an early state LL leprosy is often not diagnosed, though these patients can be extremely infective.  Awareness and skin smear may be of help.  When people do not think of leprosy it can be easily missed. 

Diffuse lepromatous leprosy (Lapati’s leprosy)
In early and late diffuse lepromatous leprosy mostly nothing is to be seen or found, only the patient may complain of some aches and pain or having the feeling of dropping things or of sleeping skin.  In late diffuse leprosy the patient looks younger and has a smooth skin due to infiltration [lepra bonita].  Skin smears in both groups of patients are positive.

Nery’s  paper addresses these problems.  Herewith I report part of the conclusions:-
<< Multibacillary (MB) leprosy, especially close to the lepromatous end of the spectrum, may mimic other diseases, and the patient cannot be diagnosed without a biopsy or a slit skin smear examination.  Leprosy should be considered in all patients with skin lesions not responding to treatment, especially when they have neurological deficits, and live or have lived in a leprosy endemic area. >>

Ben Naafs


(*)
The Diagnosis of Leprosy
S Noto, P A M Schreuder and B Naafs
Leprosy mailing list - October 2011

Times of India News


Ref.:   Ref: Times of India News [Date: 7.6.2012] 
From:
U Thakar, Mumbai, India

Dear Dr Noto,
Please, upload this important news (see attachment) on the leprosy mailing list.  Times of India News [Date: 7.6.2012].  It is about the new division specifically for the disabled at the Ministry of Health in India.

Thanks and regards,

Uday Thakar

Mr. Uday Thakar
Hon. Secretary,
Hind Kusht Nivaran Sangh-Maharashtra Branch
C/o Acworth Leprosy Hospital Research Society
Wadala, Mumbai-400031
India

Leprosy detection rate in Rio de Janeiro State, Brazil


Ref.:   Leprosy detection rate in Rio de Janeiro State, Brazil
From:
M Leide W. de Oliveira, Rio de Janeiro, Brazil



Dear Dr Theuvenet,

Thank you for your interest [LML June 4th, 2012].  Our main intention was to correlate case finding activities and early diagnosis of Hansen´s Disease (HD).  In fact there are probably many factors influencing the reduction shown:
1.
When we started with local campaigns in all 4 districts, the strategic objective was to decentralize diagnose and treatment to family health level (each family health area covers about 1000 families) in Duque de Caxias municipality.  Certainly at that time there was a hidden prevalence of HD.  The family health program did not improve significantly since 2005.  However, the Municipal Control Program assumed diagnosis and treatment as well as better contact examination in those covered areas, which includes second dose of BCG.
2.
Since 2010 we organize again local campaigns in Duque de Caxias with almost the same strategy as done in 2003.  Next year, in 2013, the campaigns will be evaluated to see if there still is evidence of hidden prevalence or not.  One preliminary observation is that new cases diagnosed in the current campaigns are mainly adults and the numbers are much less than the 1º intervention.

Since I am not an epidemiologist, there may be some exhaustion of infected persons in this region, alongside those operational factors mentioned above and besides MDT effectiveness.

MLeide W. de Oliveira
Medical School/Federal University of Rio de Janeiro.