Tuesday, September 19, 2017

(LML) InfoNTD monthly mail with latest publications on cross-cutting issues and NTDs, September 2017


Leprosy Mailing List – September 19,  2017

Ref.:  (LML)  InfoNTD  monthly mail with latest publications on cross-cutting issues and NTDs, September 2017

From:  Ilse Egers, Amsterdam, the Netherlands


Dear Pieter,


This newsletter provides you with a selection of news items and recent publications on cross-cutting issues in NTDs. Our starting point is to add articles covering a wide variety of issues. Unfortunately, this is not always possible due to a limited diversity in and shortage of articles on cross-cutting issues and NTDs.

Feel free to contact us with any questions or to receive the full text versions if a link to the full text is not included (infontd@leprastsichting.nl) . Our document delivery service is free!

Kind regards,
Ilse Egers
InfoNTD Information officer




Neglected tropical diseases course now accessible via eLearning
Geneva –– The free online eLearning Platform of the World Health Organization (WHO) now carries a section on neglected tropical diseases (NTDs) with a first course on post-kala-azar dermal leishmaniasis (PKDL). This self-learning, engaging course has rich visual content and presents information from the two main endemic geographical areas where the disease occurs.
Read more





New publications



Prospects for elimination of soil-transmitted helminths.
Ásbjörnsdóttir KH, Means AR, Werkman M, et al. Curr. Opin. Infect. Dis. 2017; 30(5):482-488.
Abstract Soil-transmitted helminths (STH) are endemic in 120 countries and are associated with substantial morbidity and loss of economic productivity. Although current WHO guidelines focus on morbidity control through mass drug administration (MDA), there is global interest in whether a strategy targeting disease elimination might be feasible in some settings. This review summarizes the prospects for switching from control to an elimination strategy.
Download PDF

Estimating the number of cases of podoconiosis in Ethiopia using geostatistical methods.
Deribe K, Cano J, Giorgi E, et al. Wellcome Open Res. 2017; 2:78.
Abstract In 2011, the World Health Organization recognized podoconiosis as one of the neglected tropical diseases. Nonetheless, the number of people with podoconiosis and the geographical distribution of the disease is poorly understood. Based on a nationwide mapping survey and geostatistical modelling, we predict the prevalence of podoconiosis and estimate the number of cases across Ethiopia.
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The Neglected Diseases: Will a ‘New World Order’ Reverse Global Gains?
Hotez PJ. Int Health. 2017; 9(5):267-268.
Download PDF

"We need people to collaborate together against this disease": A qualitative exploration of perceptions of dengue fever control in caregivers' of children under 5 years, in the Peruvian Amazon.
Frank AL, Beales ER, de Wildt G, et al. PLoS Negl Trop Dis. 2017; 11(9):e0005755.
Abstract Dengue Fever presents a significant and growing burden of disease to endemic countries, where children are at particular risk. Worldwide, no effective anti-viral treatment has been identified, thus vector control is key for disease prevention, particularly in Peru where no vaccine is currently available. This qualitative study aimed to explore the perceptions of dengue control in caregivers' of children under 5 years in Peru, to help direct future mosquito control programmes and strategy.
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Soil iron and aluminium concentrations and feet hygiene as possible predictors of Podoconiosis occurrence in Kenya.
Muli J, Gachohi J, Kagai J. PLoS Negl Trop Dis. 2017; 11(8):e0005864.
Abstract Podoconiosis (mossy foot) is a neglected non-filarial elephantiasis considered to be caused by predisposition to cumulative contact of uncovered feet to irritative red clay soil of volcanic origins in the tropical regions. Data from structured observational studies on occurrence of Podoconiosis and related factors are not available in Kenya. This study has pointed to a hitherto unreported occurrence of Podoconiosis cases and has contributed to the baseline knowledge on the occurrence of Podoconiosis in Kenya.
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Significant decline in lymphatic filariasis associated with nationwide scale-up of insecticide treated nets in Zambia.
Nsakashalo-Senkwe M, Mwase E, Chizema-Kawesha E, et al. Parasite Epidemiol Control. 2017.
Abstract Anopheline mosquitoes are primary vectors of LF in Africa, and it is possible that the significant scale-up of malaria vector control over the past decade may have also impacted LF transmission, and contributed to a decrease in prevalence in Zambia. We therefore aimed to examine the putative association between decreasing LF prevalence and increasing coverage of insecticide treated nets (ITNs) for malaria vector control.
Read more

Buruli ulcer: Case study of a neglected tropical disease.
Benbow EM, Simmonds R, Merritt RW, et al. Modeling the Transmission and Prevention of Infectious Disease. 2017; 4:105-149.
Abstract This chapter generally reviews Buruli ulcer disease within the context of neglected tropical diseases in a way that integrates the research that occurs at the molecular and cellular level of pathogen and host investigation with broader ecosystem factors that include other biological interactions (e.g., food webs) considered to be important to elucidating transmission of the pathogen, all of which must be assessed in combination to achieve successful future disease management activities.
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Ending infectious diseases in the era of the Sustainable Development Goals.
Raviglione M, Maher D. Porto Biomedical Journal. 2017.
Abstract Building on the progress made towards the Millennium Development Goals (MDGs), the World Health Organization (WHO) has developed a joint global public health approach to accelerate progress and meet the ambitious global targets set for 2030 for HIV, TB, malaria, hepatitis and NTDs in the era of the Sustainable Development Goals (SDGs).
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Progress towards elimination of lymphatic filariasis in two districts of Maharashtra: scenario of last five years.
Chaudhary SM, Kubde SS, Khamgaonkar MB. Int J Community Med Public Health. 2017; 4(9):3230-3233.
Abstract Filaria was identified as one of the diseases to be eliminated globally and its global elimination by the year 2020 has been envisaged by World Health Organization (WHO). A large coverage- compliance gap has been found in many MDA programmes in India. This study was undertaken to assess the situation of MDA coverage and compliance in two districts of Maharashtra.
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Determinants of podoconiosis, a case control study.
Feleke BE. Ethiop J Health Sci. 2017; 27(5):501.
Abstract Podoconiosis is a non-filarial swelling of lower extremity endemic in tropical regions, North America and India. The etiology and pathophysiology of the disease remain unknown. The objective of this study was to identify the determinants of Podoconiosis.
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The francophone network on neglected tropical diseases.
Jannin J, Solano P, Quick I, et al. PLoS Negl Trop Dis. 2017; 11(8):e0005738.
Download PDF

Eliminating neglected tropical diseases (NTDs) in urban settings (report).
Envision. 2017.
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Changing trends of neglected tropical diseases in China.
Li S-Z, Qian M-B, Zhang L-J, et al. Lancet Infect Dis. 2017; 17(9):901.
Abstract In The Lancet Infectious Diseases, Shigui Yang and colleagues analysed the epidemiological profiles and trends of 45 infectious diseases in China and found ten diseases substantially increasing from 2004 to 2013. Notably, two neglected tropical diseases, namely echinococcosis and schistosomiasis, had large increases, with echinococcosis increasing most, with an annual percentage change of 24·0%, and schistosomiasis increasing by the sixth largest amount, at 10·5%.
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Trachoma in the Democratic Republic of the Congo: Results of 46 baseline prevalence surveys conducted with the Global Trachoma Mapping Project.
Kilangalanga J, Ndjemba JM, Uvon PA, et al. Ophthalmic Epidemiol. 2017:1-9.
Abstract Trachoma was suspected to be endemic in parts of the Democratic Republic of the Congo (DRC). We aimed to estimate prevalences of trachomatous inflammation-follicular (TF), trichiasis, and water and sanitation (WASH) indicators in suspected-endemic Health Zones.
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A strategy for scaling up access to comprehensive care in adults with Chagas disease in endemic countries: The Bolivian Chagas Platform.
Pinazo M-J, Pinto J, Ortiz L, et al. PLoS Negl Trop Dis. 2017; 11(8):e0005770.
Abstract Bolivia has the highest prevalence of Chagas disease (CD) in the world (6.1%), with more than 607,186 people with Trypanosoma cruzi infection, most of them adults. In this context, thanks to a Spanish international cooperation collaboration, the Bolivian platform for the comprehensive care of adults with CD was created in 2009. With the collaboration and knowledge transfer activities between endemic and non-endemic countries, the platform aims to provide care, train health professionals, and create the basis for a future expansion to the National Health System of a proven model of care for adults with CD.
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Medicinal plants for the treatment of local tissue damage induced by snake venoms: An overview from traditional use to pharmacological evidence.
Félix-Silva J, Silva-Junior AA, Zucolotto SM, et al. Evid Based Complement Alternat Med. 2017; 2017.
Abstract Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. In this context, this review aimed to provide an updated overview of medicinal plants used popularly as antiophidic agents and discuss the main species with pharmacological studies supporting the uses, with emphasis on plants inhibiting local effects of snake envenomation.
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Local stakeholders’ perceptions of community sensitization for school-based deworming programme in Kenya.
Njomo DW, Masaku J, Mwende F, et al. Trop Dis Travel Med Vaccines. 2017; 3(15).
Abstract In Kenya, the National School-Based Deworming Programme (NSBDP) for soil-transmitted helminthes and schistosomiasis in prioritized areas has been going on since the year 2012. By the year 2013 over 6 million School Age Children (SAC) had been treated. To assess the local stakeholders’ perceptions of community sensitization for programme implementation, a qualitative cross-sectional survey was conducted in four-sub-counties of coastal region.
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Paediatric and maternal schistosomiasis: shifting the paradigms.
Bustinduy AL, Stothard RJ, Friedman JF. Br Med Bull. 2017.
Abstract In endemic areas, schistosomiasis causes both overt and subclinical disease in young children and their mothers, as well as in returned travellers. An action plan for paediatric schistosomiasis and female genital schistosomiasis (FGS) is needed with expanded access to praziquantel (PZQ) treatment required.
Read more

Ethiopia schistosomiasis and soil-transmitted helminthes control programme: Progress and prospects.
Negussu N, Mengistu B, Kebede B, et al. Ethiop. Med. J. 2017; 55(4):75-80.
Abstract Schistosomiasis and soil-transmitted helminthes are among seventeen WHO prioritized neglected tropical diseases that infect humans. These parasitic infections can be treated using single-dose and safe drugs. Ethiopia successfully mapped the distribution of these infections nationwide. The Ministry of Health has made a huge effort to establish neglected tropical diseases, including schistosomiasis and soil-transmitted helminthes program in the health system which helped to map majority of the woredas and initiate nationwide intervention.
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Podoconiosis in Ethiopia: From neglect to priority public health problem.
Deribe K, Kebede B, Mengistu B, et al. Ethiop. Med. J. 2017; 55(4):65-74.
Abstract Podoconiosis is a geochemical disease occurring in individuals exposed to red clay soil of volcanic origin. This Neglected Tropical Disease (NTD) is highly prevalent in Ethiopia. According to the nationwide mapping in 2013, the disease is endemic in 345 districts, where an estimated 35 million people live. The government of Ethiopia prioritized podoconiosis as one of eight priority NTDs and included it in the national integrated master plan for NTDs.
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Review of Ethiopian onchocerciasis elimination programme.
Meribo K, Kebede B, Feleke SM, et al. Ethiop. Med. J. 2017; 55(4):55-63.
Abstract Onchocerciasis is a severe parasitic infection which causes disabling skin and subcutaneous tissue changes. The disease is endemic in many African countries including Ethiopia. In 2013, Ethiopia launched Onchocerciasis elimination program with the goal of attaining interruption of onchocerciasis transmission nationwide by 2020.
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The national programme to eliminate Lymphatic filariasis from Ethiopia.
Mengistu B, Deribe K, Kebede F, et al. Ethiop. Med. J. 2017; 55(4):45-54.
Abstract Lymphatic filariasis (LF) is one of the most debilitating and disfiguring diseases common in Ethiopia and is caused by Wuchereria bancrofti. In Ethiopia, almost all LF endemic districts are co-endemic with malaria and vector control aspects of the activities are conducted in the context of malaria programme as the vectors for both diseases are mosquitoes. In order to monitor the elimination, 11 sentinel and spot-check sites have been established and baseline information has been collected.
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Is Ethiopia on track to achieving the global goal of eliminating trachoma as a public health problem by 2020?
Gebre T, Bailey R, Emerson P. Ethiop. Med. J. 2017; 55(4):33-44.
Abstract Trachoma is slated for global elimination as a public health problem by 2020. Ethiopia carries 1/3rd of the global burden of trachoma. This paper aims to explore whether Ethiopia is on track to achieve the stated goal.
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Mortality and disability-adjusted life-years (DALYS) for common neglected tropical diseases in Ethiopia, 1990-2015: Evidence from the Global Burden of Disease Study 2015.
Deribew A, Kebede B, Tessema GA, et al. Ethiop. Med. J. 2017; 55(4):3-14.
Abstract Neglected tropical diseases (NTDs) are important public health problems in Ethiopia. In 2013, the Federal Ministry of Health (FMOH) has launched a national NTD master plan to eliminate major NTDs of public health importance by 2020. Benchmarking the current status of NTDs in the country is important to monitor and evaluate the progress in the implementation of interventions and their impacts. Therefore, this study aims to assess the trends of mortality and Disability-adjusted Life-Years (DALY) for the priority NTDs over the last 25 years.
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Yaws essentials: What health professionals should know about yaws.
Hernandez DAA, Rivera AS. Heighpubs Otolaryngol and Rhinol. 2017; 1:037-040.
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Health services research in rehabilitation and disability - The time is now.
Graham JE, Middleton A, Bettger JP, et al. Arch Phys Med Rehabil. 2017.
Abstract Policy drives practice, and health services research (HSR) is at the intersection of policy, practice and patient outcomes. HSR specific to rehabilitation and disability is particularly needed. As rehabilitation researchers and providers, we are uniquely positioned to provide the evidence that guides reforms targeting rehabilitative care. We have the expertise to define the value of rehabilitation in a policy-relevant context.
Read more

The perception of disability by community groups: Stories of local understanding, beliefs and challenges in a rural part of Kenya.
Bunning K, Gona JK, Newton CR, et al. PLoS ONE. 2017; 12(8):e0182214.
Abstract Cultural narratives on disability have received much attention over the past few decades. In contexts of poverty, limited information and everyday challenges associated with having, or caring for someone with a disability, different understandings have emerged. A project was set up to promote disability awareness in neighborhood communities in a rural part of Kenya, using a process of reflection and education. This paper reports on the first aspect-reflection. The aim was to investigate local understanding of disability as a co-constructed concept.
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Important progress towards elimination of onchocerciasis in the West Region of Cameroon.
Kamga G-R, Dissak-Delon FN, Nana-Djeunga HC, et al. Parasit Vectors. 2017; 10(1):373.
Abstract After more than a decade of community-directed treatment with ivermectin (CDTI) in the West Region of Cameroon, epidemiological evaluation conducted in 2011 showed that onchocerciasis endemicity was still high in some communities. Therefore, to assess the progress made towards the elimination of onchocerciasis in the West CDTI projects, we conducted a cross-sectional survey in May 2015 in 15 unevaluated communities where the highest baseline endemicity level were found in 1996.
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Venomous snake bite in India - Why do 50,000 Indians die every year?
Menon JC, Joseph JK, Whitaker RE. J Assoc Physicians India. 2017; 65:78-81.
Abstract Snakebite is an occupational hazard causing considerable morbidity and mortality worldwide, particularly so in tropical countries like India. An estimated 50,000 Indians die due to venomous snakebite every year, seventy percent of whom are males between the ages of 20 to 50 years. Along with the associated morbidity and mortality, snakebite leads to a significant financial burden on the victim, both by way of hospital bills and labour hours lost.
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Neglected tropical diseases – Challenges and opportunities in India.
Acharya AS, Kaur R, Goel AD. INJMS. 2017.






ISNTD Water 2017
Fifth annual water, sanitation and hygiene conference and AWARDS for innovations in WASH research & technology with outstanding impact on NTDs!
November 23rd 2017
Natural History Museum, London, UK
Read more

Call for papers

Neglected Tropical Diseases and Human Rights
June 2018
Potential paper topics will focus specifically on NTDs and the right to health. Topics might include:

  • Specific case studies where rights-based approaches were used, including, for example, NTD program efforts to ensure community participation, or gender-based NTD efforts
  • Strengthening health systems to improve their capacity to respond to the human rights entitlements of people living with NTDs
  • Human rights based accountability mechanisms related to NTDs
  • Human rights informed advocacy efforts to expand NTD programs
  • Examination of NTD-related stigma and discrimination
  • Conducting NTD programs in conflict regions
  • Addressing disability associated with NTD morbidity

Papers will demonstrate strong methodological approaches, high writing quality, and robust rights-based analysis.

Submission Details

Questions about this special section can be directed to Joseph Amon at jamon@hki.org, David Addiss at daddiss@taskforce.org, Alvaro Bermejo at abermejo@ciff.org or Carmel Williams, Executive Editor, Health and Human Rights Journal at HHRsubmissions@hsph.harvard.edu

LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


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Saturday, September 2, 2017

(LML) New publications on leprosy and related issues - September 2017

Leprosy Mailing List – September 2,  2017

Ref.:    (LML) New publications on leprosy and related issues – September 2017

From:  Jiske Erlings, Amsterdam, the Netherlands

Dear Pieter,


Greetings from Infolep!

This monthly newsletter gives an overview of recent publications on leprosy and related subjects. Feel free to contact me (
infolep@leprastichting.nl) to receive the full text versions if a link to the full text is not provided. Assistance with your literature research is also possible.

Did you know that the Infolep (
www.leprosy-information.org) portal gives you access to over 26,900 publications on leprosy? Please keep sending us your recent publications for inclusion in the portal and this mailing list.

With kind regards,

Jiske Erlings
Infolep Information officer



Highlighted publications



Global leprosy update, 2016: accelerating reduction of disease burden. /
Situation de la lèpre dans le monde, 2016: accélération de la réduction de la charge de morbidité.
Wkly Epidemiol Rec. 2016 Sep 1;92(35):501-20. English, French.

Leprosy Review - 2nd issue 2017 now online

WHO Goodwill Ambassador’s Newsletter for the elimination of leprosy:

International textbook of leprosy.  
Scollard DM, Gillis TP. American Leprosy Missions. 2016.
Read online



New publications



Leprosy - we've much left to learn, but are looking to squirrels, cows and cats for insights.
J Feline Med Surg. 2017 Sep;19(9):977-978.
Read abstract

Epidemiological profile of leprosy in a municipality in the Brazilian Northeast: a retrospective analysis.
Alves ES, Braz de Oliveira L, Evangelista de Araújo TM, et al. Revista de pesquisa. 2017; 9(3):648-652.
Read abstract

Dermoscopy of borderline tuberculoid leprosy.
Ankad BS, Sakhare PS. Int J Dermatol.
2017 Aug 22.
Read abstract

Nitazoxanide is active against Mycobacterium leprae.
Bailey MA, Na H, Duthie MS, et al. PLoS ONE. 2017; 12(8):e0184107.
Download PDF

Extensive sonographic ulnar nerve enlargement above the medial epicondyle is a characteristic sign in Hansen's neuropathy.
Bathala L, N Krishnam V, Kumar HK, et al. PLoS Negl Trop Dis. 2017; 11(7):e0005766.
Download PDF

Molecular detection of Mycobacterium leprae in stained slit skin smear from leprosy patients and comparison of molecular and histopathological findings with clinical data.
Bereket A. Addis Ababa University. 2017.
Download PDF

Short-term leprosy forecasting from an expert opinion survey.
Deiner MS, Worden L, Rittel A, et al. PLoS ONE. 2017; 12(8):e0182245.
Download PDF

Characterization of leprosy in children under 15 years in an important municipality of north-eastern Brazil.
Freire de Souza CD, Silva Matos T. Mundo Saude. 2017; 41(2):130-137.
Download PDF

Field-friendly serological tests for determination of M. leprae-specific antibodies.
van Hooij A, Tjon Kon Fat EM, et al.
Sci Rep. 2017 Aug 21;7(1):8868.
Download PDF

The francophone network on neglected tropical diseases.
Jannin J, Solano P, Quick I, Debre P. PLoS Negl Trop Dis. 2017 Aug 31;11(8):e0005738.
Download PDF

Epidemiological Perspective of National Leprosy Eradication Programme in Maharashtra: Focusing on "Tribal Hot-spot" of Tribal District.
Katkar D, Mote BN, Adhav A, et al. Indian J Community Med. 2017 Jul-Sep;42(3):174-176.
Download PDF

Genome-wide Analysis of Protein-Coding Variants in Leprosy.
Liu H, Wang Z, Li Y, et al. J Invest Dermatol. 2017 Aug 22.
Read abstract

A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy.
Madigan CA, Cambier CJ, Kelly-Scumpia KM, et al. Cell. 2017; 170(5):973-985.
Download PDF

The distribution of leprosy cases with physical disability in the state of Paraiba, Brazil, from 2001 to 2011.
Malta Uchôa RE, Gonçalves de Brito KK, Malzac Freire de Santana E, et al. Revista de pesquisa. 2017; 9(3):634-340.
Read abstract

Decoding the similarities and differences among mycobacterial species.
Malhotra S, Vedithi SC, Blundell TL. PLoS Negl Trop Dis. 2017 Aug 30;11(8):e0005883.
Download PDF

Characterization of Ofloxacin Interaction with Mutated (A91V) Quinolone Resistance Determining Region of DNA Gyrase in Mycobacterium Leprae through Computational Simulation.
Nisha J, Shanthi V. Cell Biochem Biophys. 2017 Aug 18.
Read abstract

Prof. Masao Ota.
Ono T. Med Mycol J. 2017;58(3):J71-J75.
Read abstract, Some publications by Prof. Masao Ota.

An outlier in public health history in India: A.T.W. Simeons's scheme for rural medical relief, Kolhapur, 1943-47.
Pandya S. Natl Med J India. 2017 Mar-Apr;30(2):103-107.
Download PDF

Factors preventing early case detection for women affected by leprosy: a review of the literature.
Price VG. Glob Health Action. 2017 Jan - Dec;10(sup2):1360550.
Download PDF

A macrophage response to Mycobacterium leprae phenolic glycolipid initiates nerve damage in leprosy.
Ramakrishnan L, Madigan CA, Cambier CJ, et al. Cell. 2017.
Read abstract

Non-contact ulcer area calculation system for neuropathic foot ulcer.
Shah P, Mahajan S, Nageswaran S, et al. Foot and Ankle Surgery.
Read abstract

Stigma and psychological problems encountered by people with leprosy and how counselling helps: A systematic review.
Sharma D, Joshi A, Kumar P. IJIP. 2017; 4(4):176-186.
Download PDF

Fate of T cells and their secretary proteins during the progression of leprosy.
Tarique M, Saini C, Naz H, et al. Curr. Protein Pept. Sci. 2017; 18.
Read abstract

Minocycline: A strategy for unresponsive nerve function impairment.
Thangaraju P, Venkatesan S, Mk SA. Dermatol Ther. 2017 Aug 23.
Read abstract



Journals & Newsletters



Community Eye Health Journal: http://www.cehjournal.org/

Disability, CBR & Inclusive Development: http://dcidj.org/

Hansenologia Internationalis: http://www.ilsl.br/revista/atual.php

Indian Journal of Leprosy: http://www.ijl.org.in/index.html 

Leprosy Review: https://www.lepra.org.uk/Pages/FAQs/Category/volume-88
Leprosy Review Repository (1928-2001) : http://leprev.ilsl.br/arquivo.php

Plos Neglected Tropical Diseases: http://journals.plos.org/plosntds/
Revista de Leprología:
WHO Goodwill Ambassador’s Newsletter for the elimination of leprosy:



Websites & Services



Global Leprosy Programme http://www.searo.who.int/entity/global_leprosy_programme/en/

LML - Leprosy Mailing List - a free moderated email list that allows all persons interested in this theme to share ideas, information, experiences and questions.

InfoNTD - Information on cross-cutting issues in Neglected Tropical Diseases (NTDs)



LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com


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