Fw: (LML) a change in our thinking about the disease leprosy and its epidemiology

 

Leprosy Mailing List – August 19,  2020

 

Ref.:  (LML) a change in our thinking about the disease leprosy and its epidemiology

 

From:  Ben Naafs, Munnekeburen, the Netherlands

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Dear Pieter,

 

In answer to the questions of dr Laila de Laquiche, in LML 16th of this month.

 

Thank you for your reaction and I do not know where the line between a healthy carrier and a subclinical patient is. When the bacilli multiply without clinical symptoms, I would call it a subclinical disease. But the "damage" done before to a nerve, which is subclinical, I do not know how to call. There may be, or not be, serological tests which show contact with antigens. Contact with DNA may be shown with PCR but when there is no multiplication too me it is not the subclinical infectious disease: leprosy. May be, you just must call this kind of damage:  Subclinical M. leprae antigen related nerve damage (Su.ML.Rel. ND). Cannot think of a single word.

 

Concerning your doubt: like in Convid-19, tests at present may confuse clinical reasoning. But if we know which parameter goes together with the multiplication of M. leprae and we can test for that parameter it will be a real contribution. For the time being all immunological tests will only help for classification and may be detection of reactions and may be useful for epidemiological research.

 

I hope it answers some if your questions. The questions help me to make my concept clearer for myself.

 

Thanks a lot, I hope more people will contribute. May be to say and explain why it is rubbish.

 

Ben

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LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

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