Leprosy Mailing List – February 21, 2015
Ref.: (LML) How Efficacious is MDT
From: Sunil D.Ghate, Mumbai, India
Dear all,
This mail from Dr Gelber is quite informative (LML February 18, 2015).
I worked at FMR, Mumbai with Dr Shetty who initiated this discussion. We saw quite a few patients of relapse & published those results. In my private practice, I don't differentiate between MB & PB for treatment. All cases of leprosy get 3 drugs. I have started giving daily Rifampicin over past few years to all the patients; I also dose Clofazimine at 100 mg daily and Dapsone is continued at 100 mg. PB patients receive minimum of 1 year of MDT while in MB, I give up to 3 years & beyond depending on patients initial status. I try & do biopsy at the completion of Rx to ascertain that there was no activity.
Many of my colleagues also prescribe MDT for a longer duration. I feel WHO MDT MB is outdated & revision is needed even for field programmes. I don't know whether we treat any other disease with monthly dose, given for 12/24 months.
Regards.
Dr Sunil D Ghate
MD,DNB,DDV,MNAMS
Consultant Dermatologist
Mumbai,India
LML - S Deepak, B Naafs, S Noto and P Schreuder
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