Leprosy Mailing List – February 21, 2015
Ref.: (LML) NYTimes Feb. 16. 2015: Research Finds a Reason Leprosy Has Persisted
From: Indropo Agusni, Surabaya, Indonesia
Dear Dr. Schreuder,
After reading the article about M.leprae can live in amoeba, I remember about our environmental studies we conducted some years ago in East Java. Our conclusion were:
1) M.leprae can be found inside the protozoa that live in the water of some ponds in leprosy endemic areas, proved by ZN staining and PCR test.
2) By genomic study of M.leprae using TTC repeats, the variation of TTC pattern in M.leprae isolates obtained from environmental samples were similar with those M.leprae isolates obtained from human leprosy patients.
The problem of this laboratory study was the different of replication speed between the protozoa / amoeba and M.leprae. The protozoa will easily replicate and became thousand cells in hours, while M.leprae will duplicate after 2 weeks. It was very difficult to monitor the survived M.leprae inside the protozoa’s in laboratory. That is why we could not continue the study on this matter. We need advice from experts; perhaps other centers could give us some recommendations. My email address is: indropo49@gmail.com
Regards,
Prof. Indropo Agusni MD-DV
Tropical Disease Center, Airlangga University
Surabaya - Indonesia.
LML - S Deepak, B Naafs, S Noto and P Schreuder
LML blog link: http://leprosymailinglist.blogspot.it/
Contact: Dr Pieter Schreuder << editorlml@gmail.com
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