Thursday, September 13, 2018

(LML) New publications on cross-cutting issues and NTDs, September 2018

Leprosy Mailing List – September 13,  2018

Ref.:  (LML)   New publications on cross-cutting issues and NTDs, September 2018

From:  Ilse Egers, Amsterdam, the Netherlands

Dear colleagues,

This newsletter provides you with a selection of news items and recent publications on cross-cutting issues in NTDs. Our starting point is to add articles covering a wide variety of issues. Unfortunately, this is not always possible due to a limited diversity in and shortage of articles on cross-cutting issues and NTDs.

Feel free to contact us with any questions or to receive the PDF if a link to the full text is not included.
Our document delivery service is free!

Ilse Egers
InfoNTD Information officer




Samoa rolls out triple drug therapy to accelerate elimination of lymphatic filariasis.
24 August 2018 | Manila | Geneva -- Samoa has become the first country to implement the new triple drug regimen recommended by WHO for the treatment of lymphatic filariasis (LF), a disabling and disfiguring neglected tropical disease.
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New publications



Community involvement in the care of persons affected by podoconiosis—A lesson for other skin NTDs.
Tora A, Mengiste A, Davey G, et al. TropicalMed. 2018; 3(3).
Abstract Podoconiosis is a neglected tropical disease (NTD) characterized by lower-leg swelling, which is caused by long-term exposure to irritant red-clay soils found within tropical volcanic high-altitude environments with heavy rainfall. The condition places a substantial burden on affected people, their families and communities, including disability, economic consequences, social exclusion, and stigma. This paper focuses on community-based care of podoconiosis, and, in particular, the role that community involvement can have in the reduction of stigma against people affected by podoconiosis.
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Young adults in endemic areas: An untreated group in need of school-based preventive chemotherapy for schistosomiasis control and elimination.
Korir H, Riner D, Kavere E, et al. Trop Med Infect Dis. 2018; 3(3):100.
Abstract Parasitologic surveys of young adults in college and university settings are not commonly done, even in areas known to be endemic for schistosomiasis and soil-transmitted helminths. We have done a survey of 291 students and staff at the Kisumu National Polytechnic in Kisumu, Kenya, using the stool microscopy Kato-Katz (KK) method and the urine point-of-care circulating cathodic antigen (POC-CCA) test.
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Burden of leishmaniasis in Brazil and federated units, 1990-2016: Findings from Global Burden of Disease Study 2016.
Bezerra JMT, de Araújo VEM, Barbosa DS, et al. PLoS Negl Trop Dis. 2018; 12(9):e0006697.
Abstract The study presents estimates for the burden of visceral leishmaniasis (VL) and cutaneous and mucocutaneous leishmaniasis (CML) in Brazil and its 27 federated units using data from the Global Burden of Disease Study (GBD) 2016. We report the incidence, years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALY) for leishmaniasis in Brazil from 1990 to 2016. The metrics are presented as age-standardized rates per 100,000 inhabitants with their respective uncertainty intervals (95%UI) and relative percentages of change.
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Neglected tropical skin diseases in a Nigerian tertiary hospital.
Henshaw EB, Otike-Odibi BI, Okpa HO, et al. Nigerian Journal of Medicine. 2018; 27:117-122.
Abstract: Neglected tropical skin diseases (NTSD) are common in the urban dermatology clinic. The most prevalent (scabies) is a highly contagious disease, whose diagnosis remains sub-optimal among healthcare practitioners. Dermatologists are best positioned to ensure early diagnosis of a good number of NTD and stem their progression before the morbidity, disfigurement, stigmatization, and attendant short, andlong-term complications develop.
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Evaluation of mass drug administration against lymphatic filariasis in Bidar district, Karnataka, India.
Bhovi RA, Mane VP. Int J Community Med Public Health. 2018; 5(9):4107-4111.
Abstract Lymphatic filariasis is a major public health problem in India not only because it causes considerable suffering, deformity and disability but also due to social stigma and economic loss associated with it. The Government of India in 2004 began a nationwide mass drug administration (MDA) campaign. Objectives of the study were to estimate coverage and compliance to mass drug administration (MDA) in Bidar district and to identify the various reasons for non-compliance to MDA.
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Sustainability assessment tool for NTD control programmes.
CIFF, Dalberg. 2018:48.
Abstract The NTD Sustainability Assessment is a forwardlooking Excel-based tool that is set up to measure the sustainability of NTD programming. Sustainability is measured by the degree of government ownership of NTD programming. The Assessment is comprised of an integrated excel-tool as well as user manual outlining the process and templates for implementing the tool. The final output is a Findings Report with recommendations for future programming.
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"Zika is everywhere": A qualitative exploration of knowledge, attitudes and practices towards Zika virus among women of reproductive age in Iquitos, Peru.
Weldon CT, Riley-Powell AR, Aguerre IM, et al. PLoS Negl Trop Dis. 2018; 12(8):e0006708.
Abstract Zika virus was reported in the rainforest city of Iquitos, Peru in 2016. The potential associations between Zika and fetal neurological disorders were reported extensively in the media regarding neighboring Brazil, and led to great concern about the impact Zika could have on people's health in Iquitos when it arrived. The aim of this study was to explore the knowledge, attitudes, and preventative practices related to Zika virus and its transmission among women of childbearing age in Iquitos, Peru.
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When should the emphasis on schistosomiasis control move to elimination?
Secor W, Colley D. Trop Med Infect Dis. 2018; 3(3):85.
Abstract The stated goal of the World Health Organization's program on schistosomiasis is paraphrased as follows: to control morbidity and eliminate transmission where feasible. Switching from a goal of controlling morbidity to interrupting transmission may well be currently feasible in some countries in the Caribbean, some areas in South America, northern Africa, and selected endemic areas in sub-Saharan Africa where there have been improvements in sanitation and access to clean water.
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Implementation and evaluation of strategies for control of schistosomiasis and soil transmitted helminthiasis in Pemba Island, Zanzibar.
Ame SM. London School of Hygiene & Tropical Medicine. 2018.
Abstract The context of this work in Pemba was (i) the initial reestablishment of School-Based Treatment (SBT) with praziquantel (PZQ) and albendazole (ALB) for control of urogenital schistosomiasis and soil-transmitted helminths (STH), respectively, and (ii) the subsequent implementation of mass drug administration (MDA) with or without additional snail control or behavioural modification which was aimed at evaluation of the possibility of elimination of schistosomiasis.
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Elimination of schistosomiasis haematobia as a public health problem in five governorates in Upper Egypt.
Haggag AA, Rabiee A, Abd Elaziz KM, et al. Acta Trop. 2018.
Abstract The prevalence and intensity of Schistosoma haematobium infection was determined among schoolchildren living in five governorates in Upper Egypt. Between November 2016 and March 2017, urine samples were collected from 30,083 schoolchildren (6-16 years of age) from the governorates of Assiut (n = 7,496; 6 districts), Bani Sweif (n = 4,493; 7 districts), Fayoum (n = 4,597; 6 districts), Menia (n = 7,500; 9 districts) and Sohag (n = 5,997; 11 districts).
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A literature review on medicinal plants that are being used in traditional medicine for the management of the snake bites in Sri Lanka.
Mansoor NR, Sanmugarajah V. Asian plant research journal. 2018; 1(1):1-18.
Abstract Traditional Medicine is time-tested and still caters to the health needs of the society and provides health care through prophylactic treatment and rejuvenation. Today poisonous snake bites are life-threatening problems resulting in high morbidity and mortality all over the world including Sri Lanka. The medicinal plants available locally and used widely by traditional healers. Therefore they need attention in this aspect.
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Descriptive epidemiology of snakebites in the Veraguas province of Panama, 2007–2008.
Pecchio M, Suárez JA, Hesse S, et al. Trans. R. Soc. Trop. Med. Hyg. 2018.
Abstract Panama has the highest incidence of snakebites in Central America, however, few studies have looked at the epidemiology of human snakebites in Panama. This retrospective, single-center study reviewed individuals who sustained a snakebite from 2007–2008. Demographic data, disease severity, species of snake, treatment, infectious complications and antibiotic usage were collected from the hospital records.
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An economic evaluation of the global strategy to eradicate yaws.
Fitzpatrick C. Ghent University. 2018.
Abstract The economics of mass treatment for yaws is dealt with in two papers. In the first, using a regression model, we establish benchmarks for the cost per capita of mass treatment for yaws, reviewing and synthesizing evidence on the cost of mass treatment campaigns for other NTDs. In the second, we use those benchmarks in a Markov model of the cost and costeffectiveness of the yaws eradication strategy in the known endemic countries.
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Podoconiosis today: challenges and opportunities.
Deribe K. Trans. R. Soc. Trop. Med. Hyg. 2018.
Abstract Podoconiosis is a disease of significant clinical and public health importance in several endemic countries. Over the last 15 years there has been remarkable progress in research, advocacy and implementation of podoconiosis inteventions. In 2011 the World Health Organization (WHO) recognized podoconiosis as one of the neglected tropical diseases (NTDs) under the category of 'other tropical conditions'. Subsequently Ethiopia, Rwanda and Cameroon recognized podoconiosis as a priority NTD and included it in their long-term health plans.
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Impact of community-based integrated mass drug administration on schistosomiasis and soil-transmitted helminth prevalence in Togo.
Bronzan RN, Dorkenoo AM, Agbo YM, et al. PLoS Negl Trop Dis. 2018; 12(8):e0006551.
Abstract Togo has conducted annual, integrated, community-based mass drug administration (MDA) for soil-transmitted helminths (STH) and schistosomiasis since 2010. Treatment frequency and target populations are determined by disease prevalence, as measured by baseline surveys in 2007 and 2009, and WHO guidelines. Reported programmatic treatment coverage has averaged over 94%. Togo conducted a cross-sectional survey in 2015 to assess the impact of four to five years of MDA on these diseases.
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The effect of deworming school children on anemia prevalence: A systematic review and meta-analysis.
Girum T, Wasie A. Open Nurs J. 2018; 12:155-161.
Abstract High prevalence of anemia attributable to intestinal parasite infection occurs among children in developing countries. As a result mass treatment of all children with anti-helminthic drugs particularly in school setting is being implemented. We aimed to conduct a systematic review on impact assessment of deworming on anemia prevalence or hemoglobin level of school children so that policy makers and other stalk holders could have pooled evidence on the direction to make decision.
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Venomous snakebite - An outcome based analysis in a tertiary care hospital.
Subramaniam R, Swarnalatha S. Eur J Pharm Med Res. 2018; 5(5):392-397.
Abstract Snake bite is the prime of all neglected tropical diseases wherein our health care systems have little success. Though there are voluminous data on the subject, few researchers have focused on the extrinsic factors leading to adverse outcome after a venomous bite. This study aimed to elucidate the modifiable extrinsic factors which are associated with adverse outcomes after a venomous bite.
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Sustainable access to deworming drugs in a changing landscape.
Lin WM, Addiss DG. Lancet Infect Dis. 2018.
Abstract The global effort to control and eliminate soil-transmitted helminthiasis (STH) currently depends on donations of albendazole and mebendazole, which reached more than 530 million children in 2016. As we approach 2020, the WHO goal of eliminating STH as a public health problem will not be met in most endemic countries, and ongoing treatment will be necessary. Additionally, the volume of drugs required might increase because global strategies for STH aim to interrupt transmission.
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Toward the 2020 goal of soil-transmitted helminthiasis control and elimination.
Becker SL, Liwanag HJ, Snyder JS et al. PLoS Negl Trop Dis. 2018; 12(8):e0006606.
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RSTMH Annual Meeting 2018
September 19-20, London, UK
The theme of the two-day Annual Meeting is intersections of neglected tropical diseases with non-communicable diseases and the Sustainable Development Goals. Voices from different sectors will be brought together.
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NNN Annual Conference
The 9th NTD NGO Network (NNN) annual conference will take place from Monday 24th through Wednesday 26th September 2018 in Addis Ababa, Ethiopia.
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First International Podoconiosis Conference
September 23, Addis Ababa, Ethiopia
The theme is 'Research to Implementation: A Call for Global Action'.
Call for abstracts from all those involved in podoconiosis research and implementation. In order to stimulate high levels of participation, the conference programme will include two sessions of research presentations, one of implementation presentations, and a poster display area.
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LML - S Deepak, B Naafs, S Noto and P Schreuder

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Contact: Dr Pieter Schreuder <<



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