Thursday, March 19, 2020

Fw: (LML) the Maltalep study- Harm after SDR prophylaxis

 

 

 

Leprosy Mailing List – March 19,  2020

 

Ref.: (LML)  the Maltalep study- Harm after SDR prophylaxis

 

From:  Annemiek Geluk, Leiden, the Netherlands


 

Dear Pieter,

 

In the International Journal of Infectious Diseases (IJID) we have previously replied to the Letter to the Editor by Diana Lockwood, Barbara de Barros and Steve Walker (see attached)

 

The MALTALEP trial conducted in Bangladesh investigated the possibility to increase the protective effect of BCG (re)-vaccination among contacts with SDR. This combined intervention makes it unsuitable to directly compare with the results of the COLEP trial that was conducted over 10 years ago and studied the protective effect of SDR only. We have explained that in our reply to the editor of IJID. 

 

The conclusion of Lockwood et al. about the harmful effect of SDR in general cannot be based on the results of the MALTALEP trial.

 

Kind regards,

 

         Annemieke

 

Prof. dr. A. Geluk – Dept. Infectious Disease – LUMC

Immunodiagnostics of Leprosy & Tuberculosis

https://www.universiteitleiden.nl/medewerkers/annemieke-geluk 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

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