Leprosy Mailing List – May 29, 2015
Ref.: (LML) Alternative MDT drugs and treatment duration
From: Tarun Narang, Chandigarh, India
Dear Dr. Schreuder,
May I ask Dr. Warren (LML, May 29, 2015) a few questions regarding the patient she brought to our attention:
- How long is this patient on treatment;
- What is the status of the skin and nerves?
If the patient has received 1-2 years of MDT and his BI has decreased from 5 to 2 then he has responded well to treatment and we should stop treatment and observe him. That is normally done in our setup of fixed duration treatment.
Or if we want to give MDT till smear negativity the once monthly dose of Rifampicin, minocycline and Moxifloxacin (ROM) for 1-2 years can be tried. Another option is the use of immunotherapy in the form of Mycobacterium indicus pranii or BCG once in 3-4 months as adjunct to MDT in highly smear positive patients and in patients who have a high BI after 1-2 years of MDT.
Best regards,
Tarun Narang M.D
LML - S Deepak, B Naafs, S Noto and P Schreuder
LML blog link: http://leprosymailinglist.blogspot.it/
Contact: Dr Pieter Schreuder << editorlml@gmail.com
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