Sunday, February 28, 2021

Fw: (LML) Fact-based accounts are helpful in HD

 


Leprosy Mailing List – February 28 ,  2021

 

Ref.:  (LML) Fact-based accounts are helpful in HD

 

From:  Joel Almeida, London and Mumbai

 

 

Dear Pieter,

 

Apologies for errata, including a reference mistakenly omitted on 26 Feb in "(LML) Fact-based accounts are helpful in HD".

The corrected versions should read as given below (additions underlined). They are intended to convey the correct meaning.

 

Thanks

 

Joel Almeida

- - - - - - -

 

 

"These transient signs are of much less consequence than types of HD that lack specific immunity and have significant bacillary loads."

 

"Persons with "de novo" LL HD are frequently misclassified as being free from HD."

 

"Multiple drug resistance is already upon us,(4) and closing our eyes is not a helpful response. The good work of testing drugs against M. leprae, continued sporadically in some centres,(5) deserves high priority....

A survey of destitute former HD patients, in two Indian towns, found positive skin smears in 17% of them.(6) .....

References

1. Davey TF, Rees RJ. The nasal dicharge in leprosy: clinical and bacteriological aspects. Lepr Rev. 1974 Jun;45(2):121-34.

2. Cellona RV, Balagon MFV, dela Cruz EC et al. Long-term efficacy of 2 year WHO multiple drug therapy (MDT) in multibacillary (MB) leprosy patients Int J Lepr. 2003;71(4):308-19.,

3. WORKSHOP ON THE PREVENTION OF LEPROSY, POHNPEI, FEDERATED STATES OF MICRONESIA. 25-27 MAY 1999 sponsored by the Sasakawa Memorial Health Foundation Tokyo, Japan and the Western Pacific Regional Office of the World Health Organization. Int J Lepr, 67 (4) (SUPPLEMENT)

4. Rosa PS, D'Espindula HRS, Melo ACL et al. Emergence and transmission of drug/multidrug-resistant Mycobacterium leprae in a former leprosy colony in the Brazilian Amazon. Clinical Infectious Diseases. 1 July 2019, ciz570, https://doi.org/10.1093/cid/ciz570

5. Arumugam S, Joseph P, Ponnaiya J et al. Murine Model to Identify Short Duration Alternative Chemotherapy for Leprosy. Indian Journal of Leprosy 2016, 88 (3): 159-76

6. Rao PS, Mozhi NM, Thomas MV. Leprosy affected beggars as a hidden source for transmission of leprosy. Indian J Med Res. 2000 Aug;112:52-5"

 

LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

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