Alternative antibiotic regimens in leprosy

Leprosy Mailing List – January, 25^th, 2010

Ref.: Alternative antibiotic regimens in leprosy

From: David M. Scollard, Baton Rouge, LA, USA

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Further to Dr. van Brakel’s comments (LML Jan. 21^st, 2010),

In the United States we have unique medical-legal complications that make it difficult to use Clofazimine routinely for many patients. As a result, many of our physicians use minocycline (100 mg/day) routinely for adults, instead of Clofazimine. This appears to work very well as an anti-microbial regimen. Minocycline also has known anti-inflammatory properties, but we do not have evidence to clearly indicate whether it is or is not effective in preventing or treating ENL.

David

David M. Scollard, M.D., Ph.D.

Chief, Clinical Branch

National Hansen’s Disease Programs

1770 Physician Park Dr.

Baton Rouge,LA 70816

Tel: 225-756-3713

FAX: 225-756-3819

e-mail: DScollard(at)hrsa.gov

Web: www.hrsa.gov/hansens