Wednesday, September 29, 2010

Prednisolone does not reduce the effectiveness of rifampicin


Leprosy Mailing List – September 3rd, 2010

Ref.:    Prednisolone does not reduce the effectiveness of rifampicin
From:  Wim van Brakel, Amsterdam, The Netherlands



Dear Salvatore,

Dr. Shetty’s group in Mumbai just published a major study in the March issue of leprosy Review this year presenting hard evidence that prednisolone use does NOT increase the risk of relapse, i.e. does not reduce the effectiveness of rifampicin.  There is no need, therefore, to prolong MDT in patients receiving steroid treatment for reactions.

With best wishes,

Wim


Wim van Brakel, MD,MSc,PhD
Senior Advisor
KIT Development Policy & Practice
Leprosy Unit
T +31 (0)20 6939297
Royal Tropical Institute
Amsterdam
The Netherlands
F +31 (0)20 568 8444
www.kit.nl / www.kit.nl/100

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