Saturday, January 27, 2018

(LML) Chemoprophylaxis in Leprosy

Leprosy Mailing List – January 27,  2018

Ref.:    (LML) Chemoprophylaxis in Leprosy

From: Wim van Brakel, Amsterdam, the Netherlands

Dear Pieter,

I would like to react to the remark by Dr. Romero (LML, January 24, 2018) regarding the risk of developing Rifampicin resistance in case of chemoprophylaxis in leprosy.

High-level TB experts involved in work on MDR TB have assured us that single-dose rifampicin chemoprophylaxis does not pose a risk for inducing rifampicin-resistant TB. It is of course important that proper precautions and screening procedures are in place, as detailed in the attached paper. 

With kind regards,



Wim van Brakel, MD MSc PhD

Head Technical Department

Netherlands Leprosy Relief (NLR)

Wibautstraat 137k

1097DN Amsterdam


Tel. +31 20 5950529



LML - S Deepak, B Naafs, S Noto and P Schreuder

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Contact: Dr Pieter Schreuder <<


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