Tuesday, June 23, 2015

(LML) Neural leprosy

Leprosy Mailing List – June 23,  2015
Ref.:    (LML) Neural Leprosy
From:  José Antonio Garbino - ILSL, Brazil


Dear Pieter,
Referring to the request by Prof Das, LML, 21-06-2015: a  group of experts in Brazil published a systematic review about this issue - Primary Neural Leprosy: systematic review - and the full text is available in the link below:
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000600397&lng=en&nrm=iso&tlng=en
or in  www.ncbi.nlm.nih.gov/pubmed/23828524  and is also attached.

ABSTRACT
The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels of scientific evidence according to the “Oxford Centre for Evidence-based Medicine”. The following aspects were reviewed: cutaneous clinical and laboratorial investigations, i.e. skin clinical exam, smears, and biopsy, and Mitsuda's reaction; neurological investigation (anamnesis, electromyography and nerve biopsy); serological investigation and molecular testing, i.e. serological testing for the detection of the phenolic glycolipid 1 (PGL-I) and the polymerase chain reaction (PCR); and treatment (classification criteria for the definition of specific treatment, steroid treatment, and cure criteria).

Regards

José Antonio Garbino - ILSL, Bauru, SP, Brasil


LML - S Deepak, B Naafs, S Noto and P Schreuder
Contact: Dr Pieter Schreuder << editorlml@gmail.com



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