FW: (LML) MALTALEP trial - discussion

 

Leprosy Mailing List – October 26,  2019

Ref.:    (LML) MALTALEP trial - discussion

From:  Marcos Virmond, Bauru, Brazil

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Dear Pieter

 

Among the many interesting points raised by Lockwood et al. in their recent message (LML, 25-10-2019), let me stress one above all: "The reinvigoration of contact examination has been a positive outcome of chemoprophylaxis strategies and....".

 

Congratulations to Prof. Lockwood for bringing this important point back to the present discussions. Indeed, this aspect has been frequently overlooked. I stressed this positive aspect of chemoprophylaxis in an early LPEP meeting many years ago in Surabaya, Indonesia, and I am very happy that, finally, this relevant "side effect" of chemoprophylaxis is back to the discussions. Obviously, one cannot implement chemoprophylaxis for this sole reason. However, one should consider this point while discussing any chemoprophylaxis strategy.

 

Marcos Virmond

ILSL-Bauru

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LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

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FW: (LML) UN Special Rapporteur on Elimination of Discrimination against Persons Affected by Leprosy: Call for submission

 

Leprosy Mailing List – October 26,  2019

Ref.:   (LML)  UN Special Rapporteur on Elimination of Discrimination against Persons Affected by Leprosy: Call for submission

From:  Alice Cruz, Quito, Ecuator

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Dear Friends and partners,

I have the honour to address you in my capacity as Special Rapporteur on the elimination of discrimination against persons affected by leprosy and their family members, pursuant to Human Rights Council resolution 35/9. 

I would like to inform you that I will dedicate my next thematic report with focus on policy model to eliminate discrimination against person affected by leprosy and their family members. This report is due to be presented at the 44th session of the Human Rights Council in June 2020.

Accordingly, I am seeking the views and inputs of Members and observer States, National Human Rights Institutions, United Nations agencies, international and regional organizations, and civil society, including non-governmental organizations and other relevant stakeholders. You are strongly encouraged to share the questionnaire with your national or regional branches and partners. The questionnaire is also available on the website of the Office of the High Commissioner for Human Rights. (https://www.ohchr.org/EN/Issues/Leprosy/Pages/LeprosyIndex.aspx)

Please kindly take part in this consultation and submit the completed questionnaire, which will substantively inform the forthcoming report, in any of English, French or Spanish srleprosy@ohchr.org no later than 30 November 2019, using the email title: "Submissions to the Questionnaire." Where possible please limit the response to the questionnaire to 1500 words. Supporting documents can be attached. Should you need any further information or clarification to this end, please do not hesitate to contact us by email.

Thank you in advance for your valuable contribution to the work of this mandate.

Alice Cruz

Special Rapporteur on the Elimination of Discrimination against Persons Affected by Leprosy and their Family Members

 

Français

 Chers amis et partenaires,

 J'ai l'honneur de m'adresser à vous en ma qualité de Rapporteuse spéciale sur l'élimination de la discrimination à l'égard des personnes touchées par la lèpre et des membres de leur famille, conformément à la résolution 35/9 du Conseil des droits de l'homme.

Je voudrais vous informer que je consacrerai mon prochain rapport thématique sur l'élaboration d'un modèle de politique visant à éliminer la discrimination à l'égard des personnes touchées par la lèpre et des membres de leur famille. Ce rapport doit être présenté à la 44ème session du Conseil des droits de l'homme en juin 2020.

En conséquence, je sollicite les vues et les contributions des Membres et des États observateurs, des institutions nationales des droits de l'homme, des organismes des Nations Unies, des organisations internationales et régionales et de la société civile, y compris les organisations non gouvernementales et autres parties prenantes concernées. Nous vous encourageons fortement à partager le questionnaire avec vos branches et partenaires nationaux ou régionaux. Le questionnaire est également disponible sur le site Web du Haut-Commissariat aux droits de l'homme. (https://www.ohchr.org/FR/Issues/Leprosy/Pages/Call.aspx)

Merci de bien vouloir participer à cette consultation et de soumettre le questionnaire rempli, qui servira de base au prochain rapport, en anglais, français ou espagnol, à srleprosy@ohchr.org au plus tard le 30 novembre 2019, en utilisant le titre du courriel : "Soumissions au Questionnaire." Dans la mesure du possible, veuillez limiter la réponse au questionnaire à 1500 mots. Les pièces justificatives peuvent être jointes. Si vous avez besoin de plus d'informations ou d'éclaircissements à ce sujet, n'hésitez pas à nous contacter par courriel électronique.

Je vous remercie à l'avance de votre contribution aux activités de ce mandat.

Alice Cruz

Rapporteuse spéciale sur l'élimination de la discrimination à l'égard des personnes touchées par la lèpre et des membres de leur famille

 

Espagnol

Estimadas/os amigas/os y compañeras/os:

Tengo el honor de dirigirme a usted en mi calidad de Relatora Especial sobre la eliminación de la discriminación hacia las personas afectadas por la lepra y sus familiares, de conformidad con la Resolución n. º 35/9 del Consejo de Derechos Humanos de las Naciones Unidas.

 

Querría informarles que voy a dedicar mi próximo informe temático centrado en el modelo de políticas públicas para eliminar la discriminación contra las personas afectadas por la lepra y sus familiares. Este informe se presentará en el 44º período de sesiones del Consejo de Derechos Humanos en junio de 2020.

Estoy por este medio extendiendo una cordial invitación para recibir contribuciones y aportes de los Estados Miembros y Observadores; de las Instituciones Nacionales de Derechos Humanos; de los organismos, fondos y programas de las Naciones Unidas; de las organizaciones internacionales y regionales; y de la sociedad civil, incluidas las organizaciones no gubernamentales y otras partes interesadas. Se posible, les pido que compartan el cuestionario con sus sucursales y asociados, nacionales o regionales. El cuestionario también está disponible en el sitio web de la Oficina del Alto Comisionado para los Derechos Humanos: https://www.ohchr.org/SP/Issues/Leprosy/Pages/Call.aspx

Solicito amablemente que tome parte en esta consulta y envíe el cuestionario en adjunto completado en inglés, francés o español. Las respuestas se pueden enviar electrónicamente para el e-mail srleprosy@ohchr.org a más tardar el 30 de noviembre de 2019, utilizando como título del correo electrónico: "Informaciones al cuestionario". Si posible, las respuestas se pueden limitar hasta 1500 palabras. Se pueden adjuntar documentos y otros materiales complementarios. Si necesita más información o aclaraciones, no dude en ponerse en contacto con nosotros por correo electrónico.

Gracias de antemano por su valiosa contribución al trabajo de este mandato.

Alice Cruz

Relatora Especial sobre la eliminación de la discriminación contra las personas afectadas por la lepra y sus familiares

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LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

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FW: (LML) MALTALEP trial - discussion

 

Leprosy Mailing List – October 25,  2019

Ref.:    (LML) MALTALEP trial - discussion

 

From:  Diana NJ Lockwood, Barbara de Barros and Stephen L. Walker, London, UK

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Dear Pieter,

 

We would like to contribute to the important discussion of the recently published MALTALEP trial(1).  The MALTALEP trial compared the efficacy of bacillus Calmette–Guérin (BCG) vaccination  followed by single dose rifampicin (SDR) with BCG vaccination alone in preventing leprosy in household contacts and next-door neighbours of newly diagnosed leprosy patients in Bangladesh(1). It was a large, well designed cluster randomised controlled trial (RCT) and 14988 contacts of 1552 new leprosy patients were randomised to receive either BCG alone (7,378) or BCG followed by SDR (7609) 8-12 weeks later. Participants were followed up for 2 years.

 

The primary outcome of the RCT recorded in the Netherlands Trial Register (NTR3087) and reported in the trial protocol peer-reviewed publication was "New cases of leprosy among the contacts of index cases" and "…the number of new leprosy patients emerging from the contact groups" respectively(2, 3). There were no significant differences in the proportion of contacts who developed leprosy following BCG and SDR or BCG alone at one or two years. This is an important negative finding and is in keeping with the findings of the cluster randomised, double-blind, placebo-controlled COLEP trial of SDR in household and next-door neighbour contacts(4). The COLEP trial identified that the short-term benefits of SDR were only significant in more distant contacts of index cases.

 

The administration of SDR to contacts (adults and children over two years old) of individuals newly diagnosed with leprosy is recommended by WHO but the guidelines do not provide criteria to determine who is a contact(5). In two of the eight countries of the Leprosy Post-Exposure Prophylaxis (LPEP) programme contacts were restricted to the household and in only two countries were social contacts included(6). Limiting SDR to close contacts is not supported by the evidence of these two large prophylaxis RCTs.

 

A secondary data analysis was planned to "define special groups at risk for developing leprosy" and "No significant differences of interest were found."(3) The authors also discuss the non-significant 42% reduction in the number of new cases of paucibacillary leprosy in the group which received SDR after one year. We were surprised that the significant number of individuals who developed multibacillary (MB) leprosy in the SDR group by 2 years was not similarly discussed. The odds of having developed MB leprosy at the two year follow up point were 3.68 (95% CI: 1.03-13.21) in the group randomised to receive BCG and SDR compared to BCG alone. Table 6 states that only one of the 11 new cases of MB leprosy diagnosed after completion of the intervention was slit-skin smear positive.   The clinical relevance of the increased numbers of MB patients should be discussed including information about nerve function impairment.  The COLEP trial did not show any significant difference in the amount of MB disease between the SDR and placebo groups during two or four years of follow up(4).

 

The MALTALEP study has important negative findings.  It shows that SDR after BCG does not have a significant protective effect against leprosy in household and next-door neighbour contacts compared to BCG alone. This replicates the finding from the larger COLEP trial. The authors also compare data from the placebo arm of the COLEP trial with the BCG arm of the current study to infer that the protective effect of BCG is doubtful in Bangladesh.

 

SDR prophylaxis is widely promoted as an important tool in the prevention of leprosy and for interrupting transmission of M. leprae(7). Our incomplete understanding of the transmission of M. leprae and the factors influencing the development of disease hamper the discovery of an effective strategy for prevention.

 

We have concerns that the lack of clarity from WHO about the definition of contacts, the variable adherence of implementation studies to a broad definition of contacts and some contacts not being examined by trained staff may undermine any short-term benefits of SDR(6).   The reinvigoration of contact examination has been a positive outcome of chemoprophylaxis strategies and alternatives to contact examination by trained staff must be rigorously studied.

 

Implementation studies examining feasibility and acceptability of delivery of an intervention are important but are not designed to robustly measure the effect of an intervention. We agree with Richardus and colleagues that the current evidence does not support the use of BCG followed by SDR for the contacts of leprosy patients(1) and with WHO's position that the evidence for BCG alone is conflicting with no evidence of benefit(8). We disagree with some members of our community about the utility of SDR as a strategy to prevent leprosy or achieve the target of zero transmission of M. leprae. 

 

Diana NJ Lockwood

Barbara de Barros

Stephen L. Walker

 

Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine

 

References

 

1.         Richardus R, Alam K, Kundu K, Chandra Roy J, Zafar T, Chowdhury AS, et al. Effectiveness of single-dose rifampicin after BCG vaccination to prevent leprosy in close contacts of patients with newly diagnosed leprosy: A cluster randomized controlled trial. Int J Infect Dis. 2019;88:65-72.

2.         Netherlands Trial Register  [21st October 2019]. Available from: https://www.trialregister.nl/trial/2940.

3.         Richardus RA, Alam K, Pahan D, Feenstra SG, Geluk A, Richardus JH. The combined effect of chemoprophylaxis with single dose rifampicin and immunoprophylaxis with BCG to prevent leprosy in contacts of newly diagnosed leprosy cases: a cluster randomized controlled trial (MALTALEP study). BMC Infect Dis. 2013;13:456.

4.         Moet FJ, Pahan D, Oskam L, Richardus JH. Effectiveness of single dose rifampicin in preventing leprosy in close contacts of patients with newly diagnosed leprosy: cluster randomised controlled trial. BMJ. 2008;336(7647):761-4.

5.         Guidelines for the Diagnosis, Treatment and Prevention of Leprosy. New Delhi: World Health Organization, Regional Office for South-East Asia; 2018.

6.         Steinmann P, Cavaliero A, Aerts A, Anand S, Arif M, Ay SS, et al. The Leprosy Post-Exposure Prophylaxis (LPEP) programme: update and interim analysis. Leprosy Review. 2018;89(2):102-16.

7.         Smith CS, Aerts A, Kita E, Virmond M. Time to define leprosy elimination as zero leprosy transmission? Lancet Infect Dis. 2016;16(4):398-9.

8.         BCG vaccines: WHO position paper - February 2018. Wkly Epidemiol Rec. 2018;93(8):73-96.

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LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

 

 

 

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FW: (LML) InfoNTD monthly overview of the latest cross-cutting NTD publications - October, 2019

 

Leprosy Mailing List – October 25,  2019

Ref.:  (LML)  InfoNTD monthly overview of the latest cross-cutting NTD publications - October, 2019

From:  Roos Geutjes, Amsterdam, the Netherlands

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Dear Pieter and colleagues,

As the compelling list below already might suggest, making a selection for this month's overview was not so easy, as we have uploaded many interesting, inspiring and thought-provoking publications to our portal the past month. Please visit our website to find more relevant publications and tools. Have we still missed anything? Please us know!  We are counting down the weeks, as we are almost ready to launch our new website! We will keep you posted.  Warm regards, Roos Geutjes InfoNTD Coordinator www.InfoNTD.org info@InfoNTD.org

 

 

 

 

 

New publications

 

 

Access to prompt diagnosis: The missing link in preventing mental health disorders associated with neglected tropical diseases. Picado A, Nogaro S, Cruz I, Biéler S, Ruckstuhl L, Bastow J, et al.. PLoS neglected tropical diseases. 2019; 13(10):e0007679. Read more   Global programme to eliminate lymphatic filariasis: progress report, 2018 (WHO) WHO. Weekly epidemiological record. 2019; 41(94):457-472. Read more   The GRID Network: A Community of Practice for Disability Inclusive Development Cockburn L, Mbibeh L, Awa J. Disability, CBR & Inclusive Development. 2019; 30(2). Abstract This paper aimed to provide an overview of the evaluation of the GRID Network (Groups for Rehabilitation and Inclusive Development) and the impact it had on its members. Read more   Achieving universal health coverage for mental disorders. Patel V, Saxena S. BMJ (Clinical research ed.). 2019; 366l4516. Read more   The challenge of ensuring equity in mass deworming programmes. Jourdan P, Tediosi F. The Lancet. Global health. 2019. Read more   Portable infrared imaging for longitudinal limb volume monitoring in patients with lymphatic filariasis. Zhou C, Yahathugoda C, De Silva L, Rathnapala U, Owen G, Weerasooriya M, Rao RU, Weil GJ, Budge PJ. PLoS neglected tropical diseases. 2019; 13(10):e0007762. Abstract To assess the practical utility of repeated 3DIS measurements for longitudinal lymphedema management, we examined intraday and day-to-day leg volume changes in adults with filarial lymphedema in southern Sri Lanka. Read more   Identifying research priorities for psychosocial support programs in humanitarian settings. Lee C, Nguyen AJ, Haroz E, Tol W, Aules Y, Bolton P. Global Mental Health. 2019. Abstract Given the range and reach of psychosocial support (PSS) interventions in humanitarian settings, within the continuum of mental health and psychosocial support services, evaluation of their impact is critical. This project aimed to facilitate a process with stakeholders to reach consensus on PSS interventions that are of high priority for further research based on existing evidence and stakeholders' opinions. Read more   The state of community health information systems in West and Central Africa Russpatrick S, æbø J, Romedenne M, Dubent L. Journal of Global Health Reports. 2019; 3364878641034536213275. Abstract There is a clear need for community-based reporting systems to feed into a single centralized, government owned information system. Here we assess the status of centralized, government owned community health information system (CHIS) in 17 West and Central African Countries. Read more   Selecting behaviour change priorities for trachoma 'F' and 'E' interventions: A formative research study in Oromia, Ethiopia. Greenland K, White S, Sommers K, et al.. PLoS neglected tropical diseases. 2019; 13(10):e0007784. Abstract We conducted formative research in a trachoma hyper-endemic area of Ethiopia to explore the behaviours which are likely to contribute to trachoma transmission and map their determinants. Read more   Elimination of onchocerciasis in Africa by 2025: an ambitious target requires ambitious interventions. Colebunders R, Stolk WA, Siewe Fodjo J, Mackenzie CD, Hopkins A. Infectious diseases of poverty. 2019; 8(1):83. Abstract In order to reach the goal of onchocerciasis elimination in most African countries by 2025, we should prioritize community participation and advocate for tailored interventions which are scientifically proven to be effective, but currently considered to be too expensive. Read more   Are current approaches for measuring access to clean water and sanitation inclusive of people with disabilities? Comparison of individual- and household-level access between people with and without disabilities in the Tanahun district of Nepal. Banks L, White S, Biran A, Wilbur J, Neupane S, Neupane S, et al.. PloS one. 2019; 14(10):e0223557. Abstract To evaluate access to safe water, sanitation and hygiene (WASH), at the individual- and household-level, amongst people with disabilities in the Tanahun district of Nepal. Read more   Patient profiling for mental healthcare management optimization in developing countries using Datamining. AJBAL Khaoula, Samy HO, Zineb SE, et al.. International Journal of Computer Science and Information Security (IJCSIS). 2019; 17(8):11-16. Abstract Based on patient data recorded in the CPU consultation information system in 2015, we applied clustering, a Datamining technique, for the discovery of different patient profiles. Datamining can serve as useful tool for upper management as it can enable healthcare executives to make efficient knowledge driven and contextualized decisions. Read more   The association of depression, anxiety, and stress with caring for a child with Congenital Zika Syndrome in Brazil; Results of a cross-sectional study. Kuper H, Lopes Moreira M, Barreto de Araújo T, et al.. PLoS neglected tropical diseases. 2019; 13(9):e0007768. Abstract Zika virus (ZIKV) infection in pregnancy can cause microcephaly and a wide spectrum of severe adverse outcomes, collectively called "Congenital Zika Syndrome" (CZS). Parenting a child with disabilities can have adverse mental health impacts, but these associations have not been fully explored in the context of CZS in Brazil. Read more   Supervision and support in surgical practice using mobile platform: a case of mass hydrocele surgeries in remote regions Akoko L, Mwanga A, Chikawe M, Lutainulwa E, Ngoma D, Nshalla A, et al.. mHealth. 2019; 5. Abstract In Tanzania, hydrocele is more prevalent in the coastal belt, where surgical workforce is also scarce. Thus, scaling up hydrocele surgery services would require the use of non-physician clinicians (NPCs) that are currently based there by offering procedure specific training. We therefore sought to test if use of mobile platform would be an adjunct to supervision and support to practicing non surgeon clinicians in Tanzania. Read more   Snakebite and its impact in rural communities: The need for a One Health approach. Babo Martins S, Bolon I, Chappuis F, Ray N, Alcoba G, Ochoa C, et al.. PLoS neglected tropical diseases. 2019; 13(9):e0007608. Read more   Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income countries: a modelling study. Stenberg K, Hanssen O, Bertram M, et al.. The Lancet. Global health. 2019. Abstract Primary health care (PHC) is a driving force for advancing towards universal health coverage (UHC). PHC-oriented health systems bring enormous benefits but require substantial financial investments. Here, we aim to present measures for PHC investments and project the associated resource needs. Read more   Unimproved water sources and open defecation are associated with active trachoma in children in internally displaced persons camps in the Darfur States of Sudan. Macleod CK, Binnawi K, Elshafie B, Sadig H, Hassan A, Cocks N, et al.. Transactions of The Royal Society of Tropical Medicine and Hygiene. 2019; 1-11. Abstract Internally Displaced Persons camps were identified from government census data. We conducted a subanalysis of data collected in these camps during 2014-2015 as part of surveys covering 37 districts of the Darfur States within the Global Trachoma Mapping Project. Read more   Towards universal health coverage: reforming the neglected district health system in Africa. Tumusiime P, Kwamie A, Akogun OB, Elongo T, Nabyonga-Orem J. BMJ Global Health. 2019. Abstract We reviewed the situation of the district in sub-Saharan African countries and identified five attributes that are critical for developing a UHC-friendly DHS. In this analytical paper, we discuss decision-making authority, coordination, resource control, development initiative and management skills as critical factors. Read more   Proposed multidimensional framework for understanding Chagas disease healthcare barriers in the United States. Forsyth C, Meymandi S, Moss I, et al.. PLoS neglected tropical diseases. 2019; 13(9):e0007447. Abstract We propose this multidimensional framework both to explain the persistently low numbers of people with CD who are tested and treated and as a potential basis for organizing a public health response. We further argue that expanding access to diagnosis and treatment of CD in the US means asserting the rights of vulnerable populations to obtain timely, quality healthcare. Read more   State of deworming coverage and equity in low-income and middle-income countries using household health surveys: a spatiotemporal cross-sectional study. Lo NC, Heft-Neal S, Coulibaly JT, Leonard L, Bendavid E, Addiss DG. The Lancet. Global health. 2019. Abstract  This study aims to measure both coverage and equity in global, national, and subnational deworming to guide future programmatic evaluation, investment, and metric design. Read more   The rise or fall of neglected tropical diseases in East Asia Pacific. Hotez PJ. Acta tropica. 2019; 105182. Read more   Assessing the Integrated Community-Based Health Systems Strengthening initiative in northern Togo: a pragmatic effectiveness-implementation study protocol. Lauria ME, Fiori KP, Jones HE, et al.. Implementation science : IS. 2019; 14(1):92. Abstract An integrated facility- and community-based initiative, the Integrated Community-Based Health Systems Strengthening (ICBHSS) initiative, seeks to address critical gaps to access and quality of community health systems, while strengthening the public sector health system in northern Togo. This study aims to evaluate the effect and implementation strategy of the ICBHSS initiative. Read more   Sustainability of 'mHealth' interventions in sub-Saharan Africa: A stakeholder analysis of an electronic community case management project in Malawi. Dharmayat K, Tran T, Hardy V, et al.. Malawi Medical Journal. 2019. Abstract In this paper, we aim to explore barriers and facilitators for the wider implementation and sustainability of a mobile health (mHealth) intervention (Supporting LIFE Community Case Management programme) in Malawi, Africa. Read more   Challenges and way forward. Leonardo L, Bergquist R, Utzinger J, et al.. Advances in parasitology. 2019; 105125-132. Abstract Schistosomiasis, helminthic zoonoses and NTDs constitute a considerable majority of the diseases of poverty in the world. The gaps in research of those targeted zoonoses are urgently addressed by identifying the research priority, fulfilled by improving the multisectoral cooperation and strengthening the interventions in the control programme. Read more   Mental health system costs, resources and constraints in South Africa: a national survey. Docrat S, Besada D, Cleary S, Daviaud E, Lund C. Health policy and planning. 2019. Abstract The inclusion of mental health in the Sustainable Development Goals represents a global commitment to include mental health among the highest health and development priorities for investment. We conducted a national survey to quantify public expenditure on mental health and evaluate the constraints of the South African mental health system. Read more   NITR's contributions towards the elimination of Trypanosomiasis and onchocerciasis in Nigeria Enwezor FN, Mamman M, Igweh AC. Nigerian Journal of Parasitology. 2019; 40(2):252-266. Abstract This is a report on the contributions of the Nigerian Institute for Trypanosomiasis (and Onchocerciasis) Research (NITR) towards the elimination of the two Neglected Tropical Diseases. Read more   Toolkit: Woreda Level Coordination Toolkit for the WASH and NTD Sectors. Federal Ministry of Health Ethiopia. 2019. Read more   The Global Burden of Female Genital Schistosomiasis Jordens M. Faculty of Medicine and Health Sciences. 2019; Master of Medicine in Medicine46. Abstract It was the aim of this review to report the global burden of FGS, more specifically FGS prevalence and symptoms, co-infections with HIV, HPV, sexually transmitted diseases (STDs) and urinary tract infections (UTI), infertility and mortality. Read more   Comparative Assessment of Hygiene Behaviour Change and Cost-effectiveness of Community Health Clubs in Rwanda and Zimbabwe. Waterkeyn J, Matimati R, Muringaniza A, Chigono A, Ntakarutimana A, Katabarwa J, et al.. Hygiene for Human Health and Infection Control.. 2019. Abstract Two similar Community Health Club (CHC) interventions to achieve hygiene behaviour change and improved family health in Africa took place - one in Zimbabwe implemented by an NGO and the other in Rwanda part of Randomised Control Trial. Read more   Neglected tropical diseases in the People's Republic of China: progress towards elimination. Qian M-, Chen J, Bergquist R, Li Z-, Li S-, Xiao N, et al.. Infectious diseases of poverty. 2019; 8(1):86. Abstract Since the founding of the People's Republic of China in 1949, considerable progress has been made in the control and elimination of the country's initial set of 11 neglected tropical diseases. Read more   From neglect to equity vis-a-vis noncommunicable diseases and neglected tropical diseases. Krishnapillai V, Sreedevi A, Ramakrishnan D. Indian Journal of Community Medicine. 2019; 44(5). Read more   Epidemiological mapping of schistosomiasis and soil-transmitted helminthiasis for intervention strategies in Nigeria. Nduka F, Nebe OJ, N.Njepuome, et al.. Nigerian Journal of Parasitology. 2019; 40(2):218-225. Abstract This study reports on the epidemiological mapping and intervention strategies for the control of schistosomiasis and STH in Nigeria. Epidemiological survey on the prevalence of schistosomiasis and STH was conducted in Nigeria between November 2013 and May 2015 in 19 States of the Federation and the Federal Capital Territory (FCT), covering 2,160 schools /communities in 433 LGAs. Read more   Progress toward Elimination of Trachoma as a Public Health Problem in Seven Localities in the Republic of Sudan: Results from Population-Based Surveys. Sanders AM, Abdalla Z, Elshafie BE, Elsanosi M, Nute AW, Aziz N, et al.. The American journal of tropical medicine and hygiene. 2019. Abstract The Sudan FMOH conducted population-based trachoma prevalence surveys between September 2016 and April 2017 in seven localities across five states of Sudan to document current trachoma prevalence estimates and measure water, sanitation, and hygiene (WASH) indicators. Read more   Cutaneous leishmaniasis a neglected tropical disease: community knowledge, attitude and practices in an endemic area, Northwest Ethiopia. Tamiru H, Mashalla Y, Mohammed R, Tshweneagae G. BMC infectious diseases. 2019; 19(1):855. Abstract The study aimed to assess the knowledge, attitude towards cutaneous leishmaniasis and treatment seeking practices in people living in the endemic highlands areas in the Northwest, Ethiopia and to provide evidence-based information to guide development of appropriate interventions to reduce the impact of cutaneous leishmaniasis on communities. Read more   Propuestas bioéticas frente a los problemas sociales y éticos que generan las enfermedades infecciosas desatendidas. Saenz V, Mazzanti di Ruggiero MLA. Persona y Bioética. 2019. Abstract We presented, categorized, and analyzed, through a bibliographical review, the elements that relate to NTDs from the Universal Declaration of Bioethics and Human Rights, 2005, in terms of equality, justice and equity, the non-discrimination and stigmatization, social responsibility and health approach. Read more   Whatever happened to China's neglected tropical diseases? Hotez PJ. Infectious diseases of poverty. 2019; 8(1):85. Abstract China's formula for success in parasitic and neglected tropical disease control might translate to other parts of the world, such as in sub-Saharan Africa through China's new Belt and Road Initiative. Read more   Community perceptions of mass drug administration for soil-transmitted helminthiasis and schistosomiasis in selected schools in the Philippines. Lorenzo P, Manzanilla D, Cortel D, Tangog E. Infectious diseases of poverty. 2019; 8(1):87. Abstract Soil-transmitted helminthiasis (STH) and schistosomiasis are parasitic infections prevalent in tropical and subtropical countries, such as the Philippines. This study aimed to understand community knowledge and perceptions of these infections to determine their implications on the current control and elimination strategies, including possible barriers to MDA compliance. Read more

 

 

GDPR & the InfoNTD newsletter   New EU data protection regulations came into force on 25 May 2018. We have been reviewing our practices with regards to the GDPR, including our privacy statement and mailing list. InfoNTD sends out monthly e-mails to its subscribers with an overview of recent publications on NTDs and cross-cutting issues. The purpose of this activity is to keep subscribers up to date. InfoNTD will only process the data we have (names, email addresses) for the purpose of sending you the newsletter. We take your security seriously and will never share your contact details with anyone else. You can update your preferences or unsubscribe from this list at any time.

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LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 

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